A5101475364- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Wastewater Treatment and Nitrogen Removal
- Medical Imaging and Pathology Studies
- Cholesterol and Lipid Metabolism
- Membrane Separation Technologies
- Lung Cancer Treatments and Mutations
- Tuberculosis Research and Epidemiology
- Magnetism in coordination complexes
- Metal complexes synthesis and properties
- Pregnancy-related medical research
- Mycobacterium research and diagnosis
- Organometallic Complex Synthesis and Catalysis
- Hippo pathway signaling and YAP/TAZ
- Solar-Powered Water Purification Methods
- Hematological disorders and diagnostics
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Analytical Chemistry and Chromatography
- Metabolomics and Mass Spectrometry Studies
- Preterm Birth and Chorioamnionitis
- Pregnancy and preeclampsia studies
- Lung Cancer Research Studies
- Metastasis and carcinoma case studies
- Neonatal Respiratory Health Research
- Reproductive Biology and Fertility
University of Toyama
2014-2023
Shiga University of Medical Science
2018
Toneyama National Hospital
1996-2007
National Hospital Organization
2005-2007
Osaka University
1977-2004
Oita University
1996-1999
Tokyo Institute of Technology
1990-1996
Kobe University
1992
Ehime University
1992
Shizuoka University
1988
The distribution of Mycobacterium avium-intracellulare complex (MAC) in residences was examined. MAC only recovered from bathrooms but not other sites residences. appearance ratio the patients with pulmonary significantly higher than that healthy volunteers' (P = .01). For 2 patients, genotypes environmental isolates were identical to their respective clinical isolates.
Tumor metastasis is the most common cause of cancer death. Elucidation mechanism tumor therefore important in development novel, effective anti-cancer therapies to reduce mortality. Interaction between cells and surrounding stromal microenvironment a key factor metastasis. Using co-culture assay system with human prostate LNCaP primary cells, we identified epithelial membrane protein 1 (EMP1) as gene elevated expression cells. The orthotopic injection overexpressing EMP1 (EMP1-LNCaP cells)...
Aging increases oxidative stress (OS) in the ovaries, leading to infertility-related dis-orders. Granulosa cells (GCs), which support folliculogenesis are chron-ically exposed excessive OS under pathological conditions. Here, we demonstrate significant role of Rubicon, an autophagy suppressor, as a DNA damage mediator GCs OS. Hydrogen peroxide (H2O2) decreased cell viability human GC line, HGrC1, due damage, without affecting autophagic activity. However, activation increased resistance...
To improve the efficacy and selectivity of gene therapy for hepatocellular carcinoma (HCC), we designed a strategy suicide in conjunction with radiation using an HVJ-liposome vector system. The radio-inducible was constructed by insertion early growth response 1 (Egr-1) promoter upstream HSV-tk (EGF-tk). First, to test tumor specificity Egr-1, RT-PCR immunohistochemistry were performed. Egr-1 highly expressed HCC compared normal liver, where expression barely detectable. Next,...
Hydrocortisone at 10(-4) M added to macrophage cell lines had no effect on the following activities: J774.1 antibody-dependent phagocytosis and lysis of sheep RBC, RAW 264 tumor targets, latex bead by PU5-1.8 cells, constitutive production myeloid colony-stimulating activity (CSA) WEHI-3 cells. In contrast, hydrocortisone completely inhibited LPS or PPD activation functions: induced CSA, stimulation targets line, RBC line. Lower concentrations dexamethasone 10(-6) induction CSA from 55 90%....
Abstract Problem Premature ovarian insufficiency (POI) is a clinical syndrome defined by the loss of activity before 40 years old. An autoimmune mechanism suggested to be involved in development POI. Therefore, we examined relationship between peripheral blood regulatory T (Treg) cells and autoantibodies Method study Thirty POI patients 23 control women were enrolled study. Using flow cytometry, measured abundance CD4 + T, CD69 CD8 naive Treg, effector FOXP3 blood. Antinuclear...
Journal Article Systemic and cutaneous plasmacytosis with multiple skin lesions polyclonal hypergammaglobulinaemia: significant serum interleukin‐6 levels Get access A. KODAMA, KODAMA Department of Dermatology, Kobe University School Medicine, 5 Kusunoki‐cho, 7 chome, Chuo‐ku, 650, Japan Search for other works by this author on: Oxford Academic Google Scholar M. TANI, TANI Dr Tani K. HORI, HORI National Hospital, 1 Nishiochiai, 3 Suma‐ku, 654, T. TOZUKA, TOZUKA Internal MATSUI, MATSUI ITO,...
Immunoglobulin G (IgG) antibodies against purified cord factor (trehalose-6,6′-dimycolate) prepared from Mycobacterium tuberculosis H37Rv were determined by enzyme-linked immunosorbent assay (ELISA), and its diagnostic usefulness was evaluated. Serum specimens 65 patients with active pulmonary tuberculosis, 58 inactive 36 diseases other than 66 healthy adults examined. Patients showed significantly higher titers of IgG did groups (p < 0.001). The antibody titer greater 0.29 in absorption...
Whether or not serum selenium and vitamin E (alpha-tocopherol) concentrations were changed was examined among healthy families of lung cancer patients. Family members as a whole (115 sons daughters 55 patients with primary cancer) found to have trend lower levels (0.116 ± SD 0.024 μg/ml, 0.05 < P 0.1). Particularly adenocarcinoma patients, the mean level significantly (0.111 0.019 0.05) than that (0.122 0.014 μg/ml) in age-ratio matched controls who did their second-degree relatives. Serum...
Abstract Repeated oral administrations of ethanol to rats induced accumulation cholesteryl ester, as well triglyceride in the livers. The contents free cholesterol and phospholipid livers were not changed significantly present experiment which ingestions repeated four times. Although vitro esterification by particle fractions alcoholic fatty liver was affected, hydrolysis palmitate supernatant fraction homogenate reduced when compared with those control group given water or isocaloric...
Problem To investigate whether amniotic fluid ( AF ) “sludge” in patients with preterm labor PTL intact membranes is related to intra‐amniotic infection or inflammation. Method of study 105 before 29 weeks’ gestation were enrolled. was evaluated by transvaginal sonography. Microorganisms identified our newly established PCR method using a eukaryote‐made thermostable DNA polymerase. Results present 18.1% (19/105) patients. The results obtained the group vs no as follows: (i) similar positive...
Sphingosine 1-phosphate (S1P), an inflammatory mediator, is abundantly contained in red blood cells and platelets. We hypothesized that the S1P concentration peritoneal cavity would increase especially during menstrual phase due to reflux of blood, investigated human fluid (PF) from 14 non-endometriosis 19 endometriosis patients. Although relatively small number samples requires caution interpreting results, PF was predominantly increased compared non-menstrual phase, regardless presence or...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation and structure of mononuclear iron(III) complexes [LFeCl3]- [LFe(N3)3]- (L = hydrotris(1-pyrazolyl)borate hydrotris(3,5-dimethyl-1-pyrazolyl)borate)Hideno Fukui, Masami Ito, Yoshihiko Morooka, Nobumasa KitajimaCite this: Inorg. Chem. 1990, 29, 15, 2868–2870Publication Date (Print):July 1, 1990Publication History Published online1 May 2002Published inissue 1 July...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNovel formation of a linear trinuclear ferric complex containing .mu.-oxo bis(.mu.-acetato) and .mu.-hydroxo bridgeNobumasa Kitajima, Hironobu Amagai, Nobuchika Tamura, Masami Ito, Yoshihiko Morooka, Kristel Heerwegh, Alain Penicaud, Rajeev Mathur, Christopher A. Reed, Peter D. W. BoydCite this: Inorg. Chem. 1993, 32, 17, 3583–3584Publication Date (Print):August 1, 1993Publication History Published online1 May 2002Published inissue 1 August...