A5100703125- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Congenital Heart Disease Studies
- Cerebrovascular and Carotid Artery Diseases
- Cancer, Lipids, and Metabolism
- Tracheal and airway disorders
- Coronary Artery Anomalies
- Cardiac tumors and thrombi
- Gastric Cancer Management and Outcomes
- Neurological Disease Mechanisms and Treatments
- Cardiac Structural Anomalies and Repair
- Vascular anomalies and interventions
- Cardiac Imaging and Diagnostics
- Vascular Procedures and Complications
- Adrenal and Paraganglionic Tumors
- Cardiovascular Health and Disease Prevention
- Cancer-related molecular mechanisms research
- Infective Endocarditis Diagnosis and Management
- Infectious Aortic and Vascular Conditions
- Prostate Cancer Treatment and Research
- Acute Ischemic Stroke Management
- Acute Myocardial Infarction Research
- Vasculitis and related conditions
- Lysosomal Storage Disorders Research
Tianjin Medical University
2021-2025
Second Hospital of Tianjin Medical University
2021-2025
Second Affiliated Hospital of Jilin University
2018-2024
Army Medical University
2005-2022
Chongqing Medical University
2021
Xinqiao Hospital
2005-2021
Second Affiliated Hospital of Chongqing Medical University
2021
Dalian Medical University
2021
Chinese People's Liberation Army
2021
Union Hospital
2018
Aberrant lipid metabolism is a hallmark of colorectal cancer (CRC). Squalene epoxidase (SQLE), rate-limiting enzyme in cholesterol biosynthesis, upregulated CRC. Here, we aim to determine oncogenic function SQLE and its interplay with gut microbiota promoting tumourigenesis.Paired adjacent normal tissues CRC from two cohorts were analysed (n=202). Colon-specific Sqle transgenic (Sqle tg) mice generated by crossing Rosa26-lsl-Sqle Cdx2-Cre mice. Stools collected for metagenomic metabolomic...
To report early and late outcomes of patients with the primary cardiac valve tumor undergoing surgical treatment over a 30-year period in our cardiovascular center. From January 1980 to December 2014, total 211 tumors accepted treatments, which only 8 (3.8 %) were center cardiovascular. The diagnosis was identified by echocardiography preoperatively pathological analysis postoperatively. All underwent intracardiac procedures extracorporeal circulation. Intracardiac included resection on...
This study reports the early outcomes of patients with acute non-A non-B aortic dissection that involved arch but not ascending aorta.From January 2013 to December 2018, 825 presented dissection. Of these, 28 (classified as extending into entry between left common carotid artery and subclavian arteries) underwent a novel hybrid surgery. Self modified stent-grafts (Micropart Corp, Shanghai, China) were implanted via median sternotomy. Clinical presentation, postoperative data, recorded.All an...
Prostate cancer (PCa) is the world's leading type of in men. GTPase-activating protein SH3 domain-binding 1 (G3BP1) overexpressed a variety tumors. However, there are limited studies PCa concerning G3BP1. This present study was to investigates expression G3BP1 and mechanism action on PCa.We explored using TCGA database verified it clinical samples by immunohistochemistry (IHC) methods. Androgen receptor (AR) status 104 human 50 benign prostate hyperplasia (BPH) were analyzed IHC association...
Abstract Niemann-Pick type C (NP-C) disease is a neurodegenerative lysosomal storage disorder primarily caused by mutations in NPC1 . However, its pathogenesis remains poorly understood. While mounting evidence has demonstrated the involvement of long noncoding RNAs (lncRNAs) disorders, lncRNA expression profile NP-C not been determined. Here, we used RNA-seq analysis to determine and mRNA profiles cerebella −/− mice. We found that 272 lncRNAs 856 mRNAs were significantly dysregulated mice...
Objective: Transradial coronary catheterization has proved to be safe and effective in clinical practice. Various hemostatic compressive devices have been used subsequent procedures. The objective of this study was compare the efficacy safety a new compression device widely TR Band. Methods: A total 118 patients were divided randomly into two groups: Band device. Efficacy hemostasis, patient comfort, local vascular dysfunction, radial artery occlusion (RAO) evaluated compared between groups....
The worldwide mortality rate of gastric cancer remains high. Immunoglobulin-like domain containing receptor 1 (ILDR1) belongs to an evolutionarily conserved protein family, and little is known about this gene in cancer. In paper, we analyzed the expression ILDR1 its relationship with clinical outcomes using publicly available databases. ONCOMINE, GEPIA2, UALCAN, Kaplan-Meier Plotter, cBioPortal, GeneMANIA LinkedOmics databases were used analyze expression, prognostic values, mutations...
A diversity of surgical strategies are used to treat Marfan syndrome patients with aortic disease. We sought evaluate the long-term efficiency root replacement (ARR) for syndrome.Data were collected from 131 and disease who underwent ARR in our center. retrospectively analyzed outcomes these patients, among whom 68 had been diagnosed aneurysm (AA) undergone ARR. The remaining 63 dissection (AD); these, 35 limited ascending AD, while others total arch combined frozen elephant trunk (FET)....
doi: 10.1111/jocs.12103 (J Card Surg 2013;28:274–275)
To evaluate whether garlicin can attenuate reperfusion no-reflow in a catheter-based porcine model of acute myocardial infarction (AMI).Twenty-two swine were used: six sham-operation group, and eight each the control groups. The distal part left anterior descending coronary artery (LAD) latter two groups was occluded by dilated balloon for 2 hr, then reperfused 3 hr. Garlicin (1.88mg/kg) injected just before until 1 hr group. Hemodynamic data examined AMI, after occlusion, reperfusion....
Various surgical techniques have been proposed for treating aortic arch aneurysm (AAA); however, the optimal treatment has not well defined. This study introduces a new inclusion technique with frozen elephant trunk (FET) AAA treatment.
Pheochromocytoma is a rare and usually benign tumor of the adrenal glands. We report case 40-year-old woman with recurrent pheochromocytoma catecholamine cardiomyopathy. She had no history other types tumors or connective tissue disease. already undergone surgery twice to remove pheochromocytoma, which now recurred for second time. A thrombus in left ventricle was also noted upon imaging examination, dissipated after anticoagulation therapy using dabigatran, allowing patient opt an elective...
Abstract Objective: The purpose of this study was to evaluate the mid-term outcome aortic valve replacement for bicuspid and tricuspid related risk factors. Methods: From January 2014 June 2019, 177 patients 101 who underwent in our hospital were collected. 1:1 propensity score matching analysis used control bias patient selection. perioperative follow-up data between two groups compared. Independent factors which associated with continued dilatation ascending aorta identified by univariate...