A5071048047- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- Sarcoma Diagnosis and Treatment
- Palliative Care and End-of-Life Issues
- Lymphoma Diagnosis and Treatment
- Adolescent and Pediatric Healthcare
- Economic and Financial Impacts of Cancer
- Ethics and Legal Issues in Pediatric Healthcare
- Family Support in Illness
- Bone Tumor Diagnosis and Treatments
- Neutropenia and Cancer Infections
- Family and Patient Care in Intensive Care Units
- Tumors and Oncological Cases
- Multiple and Secondary Primary Cancers
- Healthcare Policy and Management
- Testicular diseases and treatments
- Management of metastatic bone disease
- Cancer survivorship and care
- Child and Adolescent Health
- Neuroblastoma Research and Treatments
- Cardiac tumors and thrombi
- Soft tissue tumor case studies
- Colorectal and Anal Carcinomas
- Thermoregulation and physiological responses
- Cutaneous lymphoproliferative disorders research
University of California, Davis
2018-2024
UC Davis Comprehensive Cancer Center
2024
Stanford Medicine
2016-2022
University of California Davis Medical Center
2020
Stanford University
2015-2018
University of Alabama at Birmingham
2017-2018
Adaptive Biotechnologies (United States)
2018
Palo Alto University
2017
Children's Hospital Colorado
2016
Community Health Center
2016
Many adult patients with cancer who know they are dying choose less intense care; additionally, high-intensity care is associated worse caregiver outcomes. Little known about intensity of end-of-life in children cancer.By using the California Office Statewide Health Planning and Development administrative database, we performed a population-based analysis aged 0 to 21 died between 2000 2011. Rates sociodemographic clinical factors previously-defined indicators were determined. The included...
In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup unique epidemiology, clinical care needs, societal impact. Comprehensive estimates in (aged 15-39 years) lacking. To address this gap, we analysed results from Global Burden Diseases, Injuries, Risk Factors Study (GBD) 2019, focus on outcome disability-adjusted life-years (DALYs), to inform control measures adults.
To identify the percentage of parents who define threshold for fever between 38.0°C and 38.3°C, which has not been reported previously, to describe parental attitudes toward antipyretic use.Thirteen-question survey study caregivers.Overall, 81% participants defined as <38.0°C, 0% correctly 19% >38.3°C. Twenty percent children brought clinic a chief complaint were never truly febrile. Ninety-three believed that high can cause brain damage. For comfortable-appearing child with fever, 89%...
BACKGROUND Adolescents and young adults (AYAs) ages 15 to 39 years with cancer continue experience disparate survival outcomes compared their younger older counterparts. This may be caused in part by differential access specialized centers (SCCs), because treatment at SCCs has been associated improved overall survival. The authors examined social clinical factors AYA use of (defined as Children's Oncology Group‐designated or National Cancer Institute‐designated centers). METHODS A...
Treatment refusal and abandonment are major causes of treatment failure for children with cancer in low- middle-income countries (LMICs), like Guatemala. This study identified risk factors described the intervention that decreased abandonment.This was a retrospective Guatemalan (0-18 years) treated at Unidad Nacional de Oncología Pediátrica (UNOP), 2001-2008, using Pediatric Oncology Network Database. to begin lapse 4 weeks or longer treatment. The impact medicina integral, multidisciplinary...
Cancer is the leading cause of nonaccidental death among adolescents and young adults (AYAs). High-intensity end-of-life care expensive may not be consistent with patient goals. However, intensity for AYA decedents cancer-especially effect received at specialty versus nonspecialty centers-remains understudied.We conducted a retrospective, population-based analysis California administrative discharge database that linked to certificates. The cohort included Californians age 15 39 years who...
Private health insurance is associated with improved outcomes in patients cancer. However, to the authors' knowledge, little known regarding impact of Patient Protection and Affordable Care Act Dependent Coverage Expansion (ACA-DCE), which extended private young adults (to age 26 years) beginning 2010, on status cancer.The current study was a retrospective, population-based analysis hospitalized adult oncology (aged 22-30 California during 2006 through 2014 (11,062 patients). Multivariable...
BACKGROUND Studies of adolescent and young adult (AYA) oncology end‐of‐life care utilization are critical because cancer is the leading cause nonaccidental AYA death contributes significantly to health expenditures. This study was designed determine quantity disparities in inpatient last year life AYAs with cancer. METHODS The California Office Statewide Health Planning Development administrative discharge database, linked certificates, used perform a population‐based analysis patients aged...
Sociodemographic and clinical factors associated with diagnostic delays in pediatric, adolescent, young adult cancers are poorly understood.
Intensity of end-of-life care receives much attention in oncology because concerns that high-intensity is inconsistent with patient goals, leads to worse caregiver outcomes, and expensive. Little known about such those undergoing allogeneic hematopoietic cell transplantation (HCT), a population at high risk for morbidity mortality.We conducted population-based analysis patients who died between 2000 2013, within 1 year an inpatient HCT using California administrative data. Previously...
Background: People with sickle cell disease (SCD) have a life expectancy of <50 years, so understanding their end-of-life care is critical. Objective: We aimed to determine where individuals SCD were dying and patterns in the year preceding death highlight research priorities possible opportunities for intervention. Design: Using California Data Collection Program database (containing administrative data, vital records, Medicaid claims), we examined people who died between 2006 2015 (cases)...
Summary Little is known about the incidence of late effects following non‐Hodgkin lymphoma (NHL) among adolescent and young adult (AYA, 15–39 years) survivors. Using data from California Cancer Registry linked to hospital discharge, we estimated cumulative at 10 years AYAs diagnosed with NHL during 1996–2012, who survived ≥2 years. Cox proportional‐hazards models were used investigate influence sociodemographic clinical factors on occurrence effects. Of 4392 HIV‐uninfected patients, highest...
Abstract Background Despite efforts to increase participation of adolescents and young adults (AYAs; 15–39 years) in cancer clinical trials (CTs), enrollment remains very low. Even when provided access CTs, AYAs are less likely participate than children older adults. A better understanding oncologist‐ AYA survivor‐reported barriers, facilitators, potential areas for CT improvement is needed. Procedures From December 2019 August 2020, we conducted 43 semi‐structured interviews with...
We examined the use of Pediatric Cancer Specialty Centers (PCSCs) over time and length stay (LOS) in pediatric oncology patients with a diagnosis febrile neutropenia. PCSCs were defined as Children's Oncology Group California Services designated centers. performed retrospective analysis on all discharges (0 to 18) neutropenia (1983 2011) using private Office Statewide Health Planning Development database. influence age, sex, race/ethnicity, payer, income, distance, tumor type, complications...
Abstract Purpose The ideal local treatment modality for pelvic and sacral Ewing sarcoma (EWS) is controversial. Methods We present the data from American College of Surgeon's National Cancer Database (NCDB) Institute's Surveillance, Epidemiology End Result (SEER) database to investigate impact modalities on survival nonmetastatic sarcoma. Local includes “surgery,” “radiation,” a combination “surgery radiation.” Results A total 235 cases SEER 285 NCDB were analyzed. Patients with “localized”...
In this population-based evaluation of adolescents and young adults (AYA) acute lymphoblastic leukemia (ALL), we describe patterns care (POC) outcomes regarding hematopoietic cell transplantation (HCT) in first complete remission (CR1). Data were abstracted from the 2013 United States Surveillance, Epidemiology, End Results POC study; newly diagnosed AYA ALL included. Multivariable logistic regression evaluated associations with HCT CR1; Cox proportional hazards survival associations. Of 399...
Primary sarcomas originating from the bones of hand and wrist are rare but carry a significant burden morbidity.National Cancer Institute's Surveillance, Epidemiology End Result database 1975 to 2017 was queried report incidence survival data in 237 patients United States. Kaplan-Meier Cox regression were used determine prognostic factors affecting survival. χ2 test assess correlation.Incidence sarcoma 0.017 per 100 000 persons has not significantly changed since (p > 0.05). Disease-specific...
Background: Soft tissue sarcomas (STS) are a heterogeneous group of tumors whose management benefits from multidisciplinary therapeutic approach. Published data suggest that cancer treatment at specialized center (SCC) can improve survival in other cancers. Therefore, we examined the impact location on children and adolescents young adults (AYAs) with STS. Methods: We performed population-based analysis AYAs hospitalized within 1 year diagnosis first primary STS (2000–2014) using California...