Lyle J. Palmer

ORCID: 0000-0002-1628-3055
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About
Contact & Profiles
Research Areas
  • Genetic Associations and Epidemiology
  • Asthma and respiratory diseases
  • Obstructive Sleep Apnea Research
  • Nutrition, Genetics, and Disease
  • Genetic Mapping and Diversity in Plants and Animals
  • Birth, Development, and Health
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Neuroscience of respiration and sleep
  • Genetic and phenotypic traits in livestock
  • Epigenetics and DNA Methylation
  • Pediatric health and respiratory diseases
  • Neonatal Respiratory Health Research
  • IL-33, ST2, and ILC Pathways
  • Respiratory and Cough-Related Research
  • Allergic Rhinitis and Sensitization
  • Obesity, Physical Activity, Diet
  • Radiomics and Machine Learning in Medical Imaging
  • Artificial Intelligence in Healthcare and Education
  • Bioinformatics and Genomic Networks
  • Cutaneous Melanoma Detection and Management
  • Genomics and Rare Diseases
  • Tracheal and airway disorders
  • Health, Environment, Cognitive Aging
  • Regulation of Appetite and Obesity
  • Lipoproteins and Cardiovascular Health

The University of Adelaide
2016-2025

Humber Teaching NHS Foundation Trust
2025

Australian Centre for Robotic Vision
2021-2024

Northern Sydney Local Health District
2024

Queen Mary University of London
2024

Instituto de Investigación Biomédica de Salamanca
2024

Centro de Investigación Biomédica en Red de Cáncer
2024

University of Colorado Denver
2016-2023

University of Bristol
2005-2021

Kennesaw State University
2017-2020

10.1038/ng.501 article EN Nature Genetics 2009-12-13

Fatty acid composition in membranes plays an important role cellular processes and has shown to be associated with the aetiology of several complex diseases humans. We report strong associations between variants human delta-5 delta-6 desaturase genes FADS1 FADS2 fatty serum phospholipids. Eighteen polymorphisms located this gene cluster were genotyped 727 adults from Erfurt, a German centre European Community Respiratory Health Survey. The is at chromosome 11q12-11q13.1, region repeatedly...

10.1093/hmg/ddl117 article EN Human Molecular Genetics 2006-05-02

Abstract Studies have shown that natural environments can enhance health and here we build upon work by examining the associations between comprehensive greenspace metrics health. We focused on a large urban population center (Toronto, Canada) related two domains combining high-resolution satellite imagery individual tree data from Toronto with questionnaire-based self-reports of general perception, cardio-metabolic conditions mental illnesses Ontario Health Study. Results multiple...

10.1038/srep11610 article EN cc-by Scientific Reports 2015-07-09

Asthma in adults may be associated with chronic airflow obstruction, possibly resulting from airway disease early life and/or a greater rate of decline lung function adult compared those asthma. Treatment and cigarette smoking also influence the function. The aim this analysis was to examine level relationship asthma adults. Subjects (n = 9,317) had participated as (> 18 years) one or more cross-sectional Busselton Health Surveys between 1966 1981 follow-up study 1994/1995. effects sex,...

10.1164/rccm.200402-230oc article EN American Journal of Respiratory and Critical Care Medicine 2004-10-15

Background: In medical imaging, prior studies have demonstrated disparate AI performance by race, yet there is no known correlation for race on imaging that would be obvious to the human expert interpreting images. Methods: Using private and public datasets we evaluate: A) quantification of deep learning models detect from images, including ability these generalize external environments across multiple modalities, B) assessment possible confounding anatomic phenotype population features,...

10.1016/s2589-7500(22)00063-2 article EN cc-by The Lancet Digital Health 2022-05-11

Rationale Lung function measures are heritable traits that predict population morbidity and mortality essential for the diagnosis of chronic obstructive pulmonary disease (COPD). Variations in many genes have been reported to affect these traits, but attempts at replication provided conflicting results. Recently, we undertook a meta-analysis Genome Wide Association Study (GWAS) results lung 20,288 individuals from general (the SpiroMeta consortium). Objectives To comprehensively analyse...

10.1371/journal.pone.0019382 article EN cc-by PLoS ONE 2011-05-20

Artificial intelligence technology has advanced rapidly in recent years and the potential to improve healthcare outcomes. However, uptake will be largely driven by clinicians, there is a paucity of data regarding attitude that clinicians have this new technology. In June-August 2019 we conducted an online survey fellows trainees three specialty colleges (ophthalmology, radiology/radiation oncology, dermatology) Australia New Zealand on artificial intelligence. There were 632 complete...

10.1038/s41598-021-84698-5 article EN cc-by Scientific Reports 2021-03-04

Corticosteroids mediate a variety of immunological actions and are commonly utilized in the treatment wide range diseases. Unfortunately, therapy with this class medications is associated large proportion non-responders significant side effects. Inhaled corticosteroids most used asthma controller therapy. However, asthmatic response to also varies widely between individuals. We investigated genetic contribution variation inhaled corticosteroid asthma. The association longitudinal change lung...

10.1093/hmg/ddh149 article EN Human Molecular Genetics 2004-05-05

10.1016/s0140-6736(07)60924-6 article EN The Lancet 2007-06-01
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