A5115749202- Innovations in Medical Education
- Problem and Project Based Learning
- Monoclonal and Polyclonal Antibodies Research
- Artificial Intelligence in Healthcare and Education
- Immunotherapy and Immune Responses
- Radiomics and Machine Learning in Medical Imaging
- Systemic Lupus Erythematosus Research
- COVID-19 diagnosis using AI
- Biomedical and Engineering Education
- Education and Critical Thinking Development
- Cancer Immunotherapy and Biomarkers
- Hormonal Regulation and Hypertension
- Clinical Reasoning and Diagnostic Skills
- Inflammatory mediators and NSAID effects
- Cancer Diagnosis and Treatment
- Smart Parking Systems Research
- Higher Education Learning Practices
- Renin-Angiotensin System Studies
- Pharmacogenetics and Drug Metabolism
- Education and Learning Interventions
- Glycosylation and Glycoproteins Research
- Engineering Education and Curriculum Development
- Galectins and Cancer Biology
- Cardiac tumors and thrombi
- Adrenal Hormones and Disorders
West China Medical Center of Sichuan University
2024
First Affiliated Hospital of Xi'an Jiaotong University
2021-2024
Sichuan University
2020-2024
Peking University
2007-2023
West China Hospital of Sichuan University
2020
University of Science and Technology of China
2018
Vanderbilt University Medical Center
2012
Ministry of Education of the People's Republic of China
2012
Chinese University of Hong Kong
2012
Problem-based learning (PBL), a pedagogical approach, is widely accepted in medical education. Manipulated by many factors, the internal motivation of learner most crucial determinant that affects nature outcome, which influences critical thinking (CT) remained elusive. One hundred two third-year undergraduate students at Peking University were involved this study. A Chinese version Critical Thinking Disposition Inventory (CTDI-CV) was used to assess CT disposition, and performance scores...
The present studies aimed at elucidating the role of prostaglandin E(2) receptor subtype 3 (E-prostanoid [EP] 3) in regulating blood pressure.Mice bearing a genetic disruption EP3 gene (EP(3)(-/-)) exhibited reduced baseline mean arterial pressure monitored by both tail-cuff and carotid catheterization. pressor responses induced agonists M&B28767 sulprostone were markedly attenuated EP3(-/-) mice, whereas reduction was comparable genotypes. Vasopressor effect acute or chronic infusion...
With the increasing interest in application of large language models (LLMs) medical field, feasibility its potential use as a standardized patient assessment is rarely evaluated. Specifically, we delved into using ChatGPT, representative LLM, transforming education by serving cost-effective alternative to patients, specifically for history-taking tasks.
<b><i>Objective:</i></b> Rheumatoid arthritis (RA) is a kind of chronic inflammatory disease characterized by the release cytokines and cardiomyocyte apoptosis, which lead to increased riskfor heart diseases. This study aims explore possible effect mechanism Celastrol on RA induced cardiac impairments in rats. <b><i>Methods:</i></b> Collagen wistar rat models (CIA) were established for measurement secondary foot swelling degree, polyarthritis...
Chemotherapy combined with immunotherapy is currently the standard first-line treatment for advanced small-cell lung cancer (SCLC). Immunotherapy can induce specific adverse events, called immune-related events (irAEs). IrAEs of bones have rarely been reported. However, identifying bone irAEs could be important in avoiding misdiagnosis and ensuring appropriate patient management. This first report describing diagnosis osteoblastic changes mimicking metastasis a SCLC treated durvalumab.
Background: Systemic lupus erythematosus (SLE) was characterized by extreme clinical heterogeneity and flare unpredictability. The immune homeostasis the basis to maintain SLE stabilization. However, there were limited data clarify association between immunophenotypes. Methods: Peripheral blood mononuclear cells obtained from 93 patients with low disease activity state (LDAS) 66 healthy individuals. Circulating B T subsets defined using flow cytometric analysis as recommended Human...
<sec> <title>BACKGROUND</title> With the increasing interest of Large Language Models’ (LLMs) application in medical field, feasibility its potential usage as a Standardized Patient (SP) assessment is rarely evaluated. Specifically, we delved into using ChatGPT, representative LLM, transforming education by serving cost-effective alternative to SPs, specifically for history-taking tasks. </sec> <title>OBJECTIVE</title> The study aims explore ChatGPT's viability and performance an SP,...
Objective To investigate the characteristics and frequencies of B cell subsets in peripheral blood rheumatoid arthritis (RA) patients, to study correlation between clinical indices influence different therapies on deeply understand pathogenesis RA. Methods Peripheral witched memory cells, non-switched naive double negative cells 141 patients 33 healthy controls were measured by flow cytometry. Patients divided into three groups based their therapeutic regimen, including tumor necrosis...
License plate detection (LPD) plays an important role in intelligent transportation system. Many LPD methods work effectively under particular scenarios or strict assumptions. However, when the processed vehicle license images lie a more complex environment, such as different illuminations, diverse state of weather, various camera equipment rotations and so on, these usually lead to poor performance. Therefore, this paper, we present novel method based on convolutional neural network (CNN)...
Despite significant recent advances in characterizing the molecular pathogenesis of undifferentiated small round cell sarcoma (USRCS), rare cases without reported gene alterations remain unclassified. To date, efficacy and prognostic biomarker immunotherapy treatment unresectable USRCS has not been demonstrated, especially when these occurring uncommon thoracic visceral organs with a novel fusion.We report case locally advanced lung (cT4N1M0) SDCCAG8-AKT3 fusion identified by RNA-based...
Based on the thorough analysis of challenges basic medical education filed in China,the School Basic Medical Sciences at Peking University has established a novel curriculum through optimization current teaching system for theory and experimental medicine implement problem-based learning (PBL) innovative scientific training program.The new been implemented class clinical students 8-year program since 2010 achieved great success. Key words: Basic education; Innovation talents; ...
The transition of medical education systems from a biomedical model to biopsychosocial along with the changes and complexities modern environment bring great challenges educators in schools all over world.Problem-based learning (PBL),is concept used enhance multidisciplinary skills using planned problem scenarios.It is an active way that increases ability students solve problems,while at same time allowing them acquire basic knowledge.As PBL focuses on cultivating...
The evaluation of problem-based learning (PBL) is different from the traditional teaching.As a part New Pathway medical education reform program in Peking University Health Science Center,School Basic Medical Sciences incorporates PBL as one major teaching methods into her new curriculum and has established unique system,which includes both formative summative implement eight-year students. Key words: Problem-based learning; Teaching method; student; Assessment system
Objective To investigate the influence of 3 components in problem-based learning system, that is students, tutors and cases, on critical thinking ability undergraduate medical students. Methods A total 114 students grade 2013 Peking University were involved this study. The scores student performance, tutor performance case quality collected after PBL teaching. Chinese version disposition inventory (CTDI-CV) was used to assess ability. Multiple linear regression analysis with CTDI-CV...
Objective To investigate the learning burnout in problem-based and its influential factors. Methods The third-year undergraduate medical students, including 8-year track 5-year Peking University were involved this study. The scores of student performance, tutor performance case quality collected after cases learning. students' attitude PBL surveyed with 3 in-house designed questions. Learning Burnout Scale for college students was used before PBL. Correlation analyzed between 4...
Abstract Background: The programmed cell death protein 1 receptor (PD-1) is an immune-checkpoint that negatively regulates the immune system to avoid collateral damage self-tissues. Tumors hijack this mechanism as a way detection and destruction. Presently, FDA has approved three anti-PD-1 antibodies for treatment in more than ten cancer types. CS1003 novel mAb recognizing unique epitope developed disrupt PD-1 interaction with PD-L1/PD-L2 restore or improve T-cell function stand-alone...
Objective To explore the prevalence of vitamin D deficiency in new onset and treatment-naive systemic lupus erythematosus (SLE) patients study correlation between serum 25(OH)D values disease activity SLE. Methods A retrospective case series analysis was done 117 new-onset SLE hospitalized during May 2016 2017 Department Rheumatology First Affiliated Hospital Xi'an Jiaotong University 39 age gender matched healthy controls. Cinical demographic details were collected. Disease evaluated...