Lu Li

ORCID: 0009-0001-1145-5428
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About
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Research Areas
  • Lung Cancer Treatments and Mutations
  • Ferroptosis and cancer prognosis
  • Lung Cancer Diagnosis and Treatment
  • Privacy-Preserving Technologies in Data
  • Cryptography and Data Security
  • Lung Cancer Research Studies
  • Cancer, Lipids, and Metabolism
  • RNA modifications and cancer
  • Cancer Immunotherapy and Biomarkers
  • Prostate Cancer Diagnosis and Treatment
  • Medical Imaging and Pathology Studies
  • Respiratory Support and Mechanisms
  • Winter Sports Injuries and Performance
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Colorectal Cancer Treatments and Studies
  • Photoreceptor and optogenetics research
  • Mobile Crowdsensing and Crowdsourcing
  • Cancer, Hypoxia, and Metabolism
  • Internet Traffic Analysis and Secure E-voting
  • Advanced Fluorescence Microscopy Techniques
  • Occupational and environmental lung diseases
  • Radiomics and Machine Learning in Medical Imaging
  • Blockchain Technology Applications and Security
  • Sarcoma Diagnosis and Treatment
  • Cancer Genomics and Diagnostics

Capital Medical University
2025

Ningxia Medical University
2025

Southwestern University of Finance and Economics
2025

Children's Hospital of Zhejiang University
2025

Zhengzhou Central Hospital
2022-2025

Beijing Friendship Hospital
2025

Sichuan Mianyang 404 Hospital
2024

University of Science and Technology of China
2013-2024

Xi'an Medical University
2023-2024

Bengbu Medical College
2023-2024

Abstract Maintaining homeostasis of the decidual immune microenvironment at maternal–fetal interface is essential for placentation and reproductive success. Although distinct cell subpopulations have been identified under normal conditions, systematic understanding spectrum heterogeneity leukocytes recurrent miscarriage in human deciduas remains unclear. To address this, we profiled respective transcriptomes 18,646 primary cells isolated from patients with pregnancy loss (RPL) healthy...

10.1038/s41421-020-00236-z article EN cc-by Cell Discovery 2021-01-04

This study aimed to assess the protective effect of a clinical dose esketamine on cerebral ischemia/reperfusion (I/R) injury and reveal potential mechanisms associated with microglial polarization autophagy. Experimental ischemia was induced by middle artery occlusion (MCAO) in adult rats simulated oxygen-glucose deprivation (OGD) BV-2 cells. Neurological sensorimotor function, infarct volume, histopathological changes, mitochondrial morphological apoptosis ischemic brain tissues were...

10.2147/dddt.s504179 article EN cc-by-nc Drug Design Development and Therapy 2025-01-01

This paper investigates the optimal robust equilibrium investment and reinsurance strategy in a model with common shock dependent claims for an ambiguity-averse insurer (AAI). Suppose that insurance company can purchase proportional whose premium is calculated by expected value principle to disperse risks. The insurer’s wealth process have two classes of business surplus be invested financial market composed one risk-free asset risky asset, where asset’s price characterized constant...

10.1371/journal.pone.0316649 article EN cc-by PLoS ONE 2025-02-28

We have recently shown that δ-opioid receptors (DORs) play an important role in neuroprotection from hypoxic injury via the regulation of extracellular signaling-regulated kinase (ERK) and cytochrome c release. Since ERK are differentially involved caspase signaling oxidative significantly contributes to neuronal damage ischemia/reperfusion, we considered if DOR activation protects ischemic brain by attenuating injury. observed that, a model cerebral ischemia with middle artery occlusion,...

10.1186/1741-7007-7-55 article EN cc-by BMC Biology 2009-08-26

Ferroptosis is a type of cell death characterized by iron-dependent phospholipid peroxidation and reactive oxygen species overproduction. induces immunogenic elicits anti-tumor immune responses, playing an important role in cancer immunotherapy. suppression cells impairs its immunotherapeutic efficacy. To overcome this issue, ferroptosis inducers (FINs) have been combined with other therapies to create microenvironment. However, the ferroptosis-based crosstalk between tumor complex because...

10.1016/j.cytogfr.2023.08.004 article EN cc-by-nc-nd Cytokine & Growth Factor Reviews 2023-08-20

Truthful spectrum auctions have been extensively studied in recent years. Truthfulness makes bidders bid their true valuations, simplifying greatly the analysis of auctions. However, revealing one's valuation causes severe privacy disclosure to auctioneer and other bidders. To make things worse, previous work on secure does not provide adequate security. In this paper, based TRUST, we propose PS-TRUST, a provably solution for truthful double Besides maintaining properties truthfulness...

10.1109/infocom.2014.6848057 article EN IEEE INFOCOM 2022 - IEEE Conference on Computer Communications 2014-04-01

Spatial Crowdsourcing (SC) nowadays has become a popular research topic studying how to outsource set of spatial-temporal tasks workers at specific locations. However, there exists significant security concern: existing location privacy techniques are not applicable SC. In this paper, we focus on protecting the worker against semi-honest adversaries model while preserving functionality SC system. By introducing third party and using additive homomorphic encryption, present secure task...

10.1109/glocom.2015.7416965 article EN 2015 IEEE Global Communications Conference (GLOBECOM) 2015-12-01

The purpose was to provide an overview of genotype and phenotype distribution in a cohort patients with Charcot-Marie-Tooth disease (CMT) related disorders from central south China.In all, 435 were enrolled detailed clinical data collected. Multiplex ligation-dependent probe amplification for PMP22 duplication/deletion CMT multi-gene panel sequencing performed. Whole exome further applied the remaining who failed achieve molecular diagnosis.Among patients, 216 had CMT1, 14 hereditary...

10.1111/ene.15024 article EN European Journal of Neurology 2021-07-13

The objective of this study is to investigate the effect after application Failure Model and Effect Analysis (FMEA) in nursing care for patients who have undergone endoscopic submucosal dissection (ESD). A cohort 40 underwent ESD between July September 2023 were selected as control group, while 42 October June 2024 implementing FMEA observation group. multidisciplinary team was established based on model analyze create a flowchart. 3 primary processes 13 sub-processes thoroughly analyzed...

10.1186/s12912-025-02692-y article EN cc-by-nc-nd BMC Nursing 2025-01-14

Abstract Background The relationship between time‐averaged serum uric acid (TA‐SUA) levels and prognosis in peritoneal dialysis (PD) patients are rarely discussed. Methods This was a retrospective cohort study. PD recruited from January 1, 2011, to December 31, 2020, were included. Baseline follow‐up over 1 year collected calculate levels. Patients divided into four groups based on TA‐SUA quartiles: Q1 (<5.1 mg/dl), Q2 (5.1–5.8 Q3 (5.8–6.8 Q4 (>6.8 mg/dl). Results A total 487 with mean...

10.1111/1744-9987.14252 article EN cc-by-nc Therapeutic Apheresis and Dialysis 2025-02-04

Spatial Crowdsourcing (SC) nowadays has become a popular research topic studying how to outsource set of spatial-temporal tasks workers at specific locations. However, there exists significant security concern: existing location privacy techniques are not applicable SC. In this paper, we focus on protecting the worker against semi-honest adversaries model while preserving functionality SC system. By introducing third party and using additive homomorphic encryption, present secure task...

10.1109/glocom.2014.7416965 article EN 2015 IEEE Global Communications Conference (GLOBECOM) 2014-12-01

Breast cancer is the second leading cause of death in women, thus a reliable prognostic model for overall survival (OS) breast needed to improve treatment and care. Ferroptosis an iron-dependent cell death. It already known that siramesine lapatinib could induce ferroptosis cells, some ferroptosis-related genes were closely related with outcomes treatments regarding cancer. The relationship between these prognosis OS remains unclear. data gene expression clinical information was downloaded...

10.3390/biology10020151 article EN cc-by Biology 2021-02-14

Abstract Background This report describes an outbreak of 71 patients developed B. cepacia urinary tract infection (UTI) by contaminated single-use anesthetic gel. Methods Epidemiological investigation with -positive urine or blood samples between March 19, 2018 and Novemeber 15, was conducted to identify the source infection. Microbiological from hospital surfaces, endoscopes, disposable items, hands staff were tested for contamination. Pulsed-field gel electrophoresis (PFGE) used compare...

10.1186/s13756-020-00855-x article EN cc-by Antimicrobial Resistance and Infection Control 2021-01-06

In response to diffused ionizing radiation damage throughout the body caused by nuclear leaks and inaccurate radiotherapy, radioprotectants with considerable free radical scavenging capacities, along negligible adverse effects, are highly regarded. Herein, unlike being performed as toxic chemotherapeutic drug candidates, molybdenum-based polyoxometalate nanoclusters (Mo-POM NCs) were developed a non-toxic potent radioprotectant impressive capacities for protection. comparison clinically used...

10.1021/acsami.2c19282 article EN ACS Applied Materials & Interfaces 2023-01-26

Epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) are a response to EGFR-tyrosine kinase inhibitor. However, lack of sufficient tumor tissue has been limitation for determining EGFR mutation status clinical practice. The objective this study was predict NSCLC patients based on model including maximum standardized uptake value (SUVmax) and features. We retrospectively reviewed undergoing testing pretreatment positron emission tomography/computed...

10.1097/md.0000000000004421 article EN cc-by-nc Medicine 2016-07-01
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