A5073758402- Health Systems, Economic Evaluations, Quality of Life
- Neuroscience and Neuropharmacology Research
- Alzheimer's disease research and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Clinical practice guidelines implementation
- Sleep and Wakefulness Research
- Blood Pressure and Hypertension Studies
- Schizophrenia research and treatment
- Chronic Kidney Disease and Diabetes
- RNA Interference and Gene Delivery
- Neurogenesis and neuroplasticity mechanisms
- Primary Care and Health Outcomes
- Genetic Associations and Epidemiology
- Nerve injury and regeneration
- Neuropeptides and Animal Physiology
- Epigenetics and DNA Methylation
- Adipose Tissue and Metabolism
- Cholinesterase and Neurodegenerative Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
King Saud University
2023
King Saud Medical City
2023
Universidad Autónoma de Madrid
2006-2015
Research Institute Hospital 12 de Octubre
2010
Hospital Universitario 12 De Octubre
2009
Abstract The functional Val158Met polymorphism (rs4680) located at the gene that codes for catechol‐ O ‐methyltransferase ( COMT ) has been extensively investigated in schizophrenia although current data are still controversial. Since activity is sexually dimorphic, we carried out two independent studies homogeneous samples of male and female Spanish schizophrenic patients. In males, found an association between homozygous Val genotype disorder, which resembled a recessive model P = 0.022;...
Saudi Arabia's ambitious Vision 2030 project was launched in 2016 as a strategy for economic development and national growth, with 11 Realization Programs put charge of its implementation. The backbone Transformation Program the Health Sector has been definition new Model Care aiming to deliver 42 coordinated interventions across 6 Systems Care, clinical guidelines identified key cross-cutting intervention foster use national, evidence-based practices KSA, reduce care variation, promote...
Background: This practice guideline was developed by the Chronic Kidney Disease (CKD) Task Force, which composed of clinical and methodological experts. The Saudi Arabian Ministry Health its Holding Company commissioned this project to support realization Vision 2030's healthcare transformation pillar. Methods: synthesis guided GRADE-ADOLOPMENT methodology. Results: final adoloped addressed 12 questions on blood pressure management in patients with CKD through a set recommendations...
This practice guideline was developed by the chronic kidney disease (CKD) Task Force, which composed of clinical and methodological experts. The Saudi Arabian Ministry Health its health holding company commissioned this project to support realization Vision 2030's health-care transformation pillar. synthesis these guidelines guided Grading Recommendations Assessment, Development, Evaluation (GRADE)- ADOLOPMENT methodology. final addressed 12 questions on management blood pressure in patients...
Little is known about the role of lipoprotein receptor-related protein-2 (LRP2)/megalin in central nervous system (CNS). Previous studies have indicated that megalin, an endocytic receptor binds multiple ligands, expressed ventricular ependymal cells, choroid plexus epithelium, and endothelial but absent from neurons adult brain. It likely structures where megalin has been detected it participates endocytosis transport amyloid β-peptide (Aβ) complex across vascular membranes, including...