A5100370905- Cancer Genomics and Diagnostics
- Acute Lymphoblastic Leukemia research
- Prostate Cancer Treatment and Research
- Pancreatic and Hepatic Oncology Research
- Traditional Chinese Medicine Analysis
- Sarcoma Diagnosis and Treatment
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Cancer Cells and Metastasis
- Receptor Mechanisms and Signaling
- Antimicrobial Peptides and Activities
- CAR-T cell therapy research
- Inflammatory mediators and NSAID effects
- Reproductive tract infections research
- Genetic factors in colorectal cancer
- RNA Interference and Gene Delivery
- Ferroptosis and cancer prognosis
- Bacterial biofilms and quorum sensing
- Antimicrobial agents and applications
- Plant-based Medicinal Research
- Electron Spin Resonance Studies
- Botany and Plant Ecology Studies
- Bioactive Natural Diterpenoids Research
- Bryophyte Studies and Records
- Immune Response and Inflammation
Sun Yat-sen University
2013-2025
Sun Yat-sen University Cancer Center
2025
First Affiliated Hospital of Henan University
2017-2024
Fujian Medical University
2021-2024
Ministry of Education of the People's Republic of China
2024
Air Force Engineering University
2024
Air Force Medical University
2024
Anhui University of Traditional Chinese Medicine
2024
Xiangya Hospital Central South University
2019-2024
Central South University
2006-2024
Introduction: Antibiotics are used to treat bacterial infections by killing the bacteria or inhibiting their growth, but resistance antibiotics can develop readily. The discovery that quorum-sensing regulates virulence as well formation of biofilms opens up new ways control certain infections. Furanone compounds capable systems have been isolated from marine macro alga Delisea pulchra.
Laser ablation MC-ICP-MS allows in situ strontium isotope data to be obtained for incrementally formed bioapatites such as enamel with extremely high spatial resolution. Here, we provide a large-scale application of the method comparing ...Understanding mobility and landscape use is important reconstructing subsistence behavior, range, group size, it may contribute our understanding phenomena dynamics biological cultural interactions between distinct ...
REVIEW article Front. Microbiol., 01 July 2011Sec. Cellular and Infection Microbiology - closed section volume 2 2011 | https://doi.org/10.3389/fmicb.2011.00107
Abstract Obesity is usually considered to predispose atherosclerotic cardiovascular disease (ASCVD) but milder degrees of obesity or overweight may be protective in some elderly populations. We examined the relationships between general and abdominal indices with ASCVD its risk factors (aged ≥65 years) Shanghai community residents Among 3950 participants, 21.5% had ASCVD, 56.2% body mass index (BMI) ≥24 kg/m2, 50.1% high waist circumference (WC) 77.1% waist-to-height ratio (WHtR) ≥0.50. WHtR...
Large-scale treatment of oily water arising from frequent marine oil spills presents a major challenge to scientists and engineers. Although the recently emerged phase-selective organogelators (PSOG) do offer very best promises for spill treatment, there still exists number technical barriers overcome collectively, including gelators' high solubility, gelling ability, general applicability toward crude various types, rapid gelation with room temperature operation, low toxicity, cost. Here,...
Background. Quinolone-resistant Neisseria gonorrhoeae (QRNG) arise from mutations in gyrA (intermediate resistance) or and parC (resistance). Here we tested the consequence of commonly isolated gyrA91/95 parC86 on gonococcal fitness.
ABSTRACT Resistance to β-lactam antibiotics is a frequent problem in Pseudomonas aeruginosa lung infection of cystic fibrosis (CF) patients. This resistance mainly due the hyperproduction chromosomally encoded β-lactamase and biofilm formation. The purpose this study was investigate role pharmacokinetics (PK) pharmacodynamics (PD) ceftazidime imipenem on P. biofilms. PAO1 its corresponding β-lactamase-overproducing mutant, PAΔDDh2Dh3, were used study. Biofilms these two strains flow...
Nano-dagger coated gauze was bactericidal against both Gram-positive and Gram-negative bacteria, with log reduction >7 for Escherichia coli (E. coli) Staphylococcus aureus (S. aureus). Compared the commercially available Ag gauze, ZIF-L nano-dagger more biocompatible a lower haemolytic activity, less cytotoxicity improved wound healing performance. Animal studies showed that can effectively kill bacteria in S. infection model mice. This novel offers an effective safe alternative patients to...
The steady development of bacterial resistance has become a global public health issue, and new antibacterial agents that are active against drug-resistant bacteria less susceptible to urgently needed. Here, series low-molecular-weight cationic polylysines (Cx-PLLn) with different hydrophobic end groups (Cx) degrees polymerization (PLLn) was synthesized used in applications. All the obtained Cx-PLLn have activity. Among them, C6-PLL13 displays best effect for Gram-positive bacteria, is,...
ABSTRACT Two chemotactic transducers for inorganic phosphate (P i ), designated CtpH and CtpL, have been identified in Pseudomonas aeruginosa . The corresponding genes ( ctpH ctpL ) were inactivated by inserting kanamycin tetracycline resistance gene cassettes into the wild-type P. PAO1 genome. Computer-assisted capillary assays showed that single mutant failed to exhibit P taxis when concentration of was higher than 5 mM. Conversely, could not respond at 0.01 double defective any ranging...
Lipoprotein lipase (LPL) hydrolyzes circulating triglycerides (TGs), releasing fatty acids (FA) and promoting lipid storage in white adipose tissue (WAT). However, the mechanisms regulating LPL its relationship with development of hypertriglyceridemia are largely unknown. WAT from obese humans exhibited high PAR2 expression, which was inversely correlated gene. Decreased expression also elevated plasma TG levels, suggesting that might regulate by downregulating LPL. In mice, aging palmitic...