Arielle C. Coughlin

ORCID: 0000-0002-1951-7849
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About
Contact & Profiles
Research Areas
  • Fungal and yeast genetics research
  • Mitochondrial Function and Pathology
  • Diabetes Management and Research
  • Retinal Imaging and Analysis
  • Retinal Diseases and Treatments
  • Genetic Neurodegenerative Diseases
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Ocular Diseases and Behçet’s Syndrome
  • Gestational Diabetes Research and Management
  • Esophageal Cancer Research and Treatment
  • Long-Term Effects of COVID-19
  • Venous Thromboembolism Diagnosis and Management
  • Autoimmune Neurological Disorders and Treatments
  • Traumatic Ocular and Foreign Body Injuries
  • Pectus Deformity Diagnosis and Treatment
  • Cervical Cancer and HPV Research
  • Cerebral Venous Sinus Thrombosis
  • Birth, Development, and Health
  • Renal and related cancers
  • Reproductive System and Pregnancy
  • Pelvic floor disorders treatments
  • Enhanced Recovery After Surgery
  • Peripheral Neuropathies and Disorders
  • Pediatric Urology and Nephrology Studies
  • Reproductive Health and Technologies

Columbia University Irving Medical Center
2024

Icahn School of Medicine at Mount Sinai
2020-2024

Community Link
2024

Mount Sinai Hospital
2023

Columbia University
2021-2022

New York Proton Center
2022

Soft drusen and subretinal drusenoid deposits (SDDs) characterize two pathways to advanced age-related macular degeneration (AMD), with distinct genetic risks, serum associated systemic diseases.One hundred twenty-six subjects AMD were classified as SDD (with or without soft drusen) non-SDD (drusen only) by retinal imaging, testing, histories of cardiovascular disease (CVD) stroke.There 62 64 subjects, whom 51 had CVD stroke. correlated significantly lower mean high-density lipoprotein (61 ±...

10.1097/iae.0000000000003460 article EN Retina 2022-02-25

Abstract In yeast, actin cables are F-actin bundles that essential for cell division through their function as tracks cargo movement from mother to daughter cell. Actin also affect yeast lifespan by promoting transport and inheritance of higher-functioning mitochondria cells. Here, we report cable stability declines with age. Our genome-wide screen genes identified the open reading frame YKL075C . Deletion results in increases abundance, mitochondrial fitness, replicative lifespan....

10.1038/s41467-022-30045-9 article EN cc-by Nature Communications 2022-05-16

To assess whether universal use of every-other-day glucose monitoring in patients with gestational diabetes mellitus (GDM) resulted similar birth weights and medication was preferred by the patient compared traditional daily monitoring.

10.1097/aog.0000000000005528 article EN Obstetrics and Gynecology 2024-02-08
Hila Milo Rasouly Sarath Babu Krishna Murthy Natalie Vena Gundula Povysil Andrew Beenken and 95 more Miguel Verbitsky Shirlee Shril Iris Lekkerkerker Atlas Khan David Fasel Janewit Wongboonsin Jeremiah Martino Juntao Ke Naama Elefant Nikita Tomar Ofek Harnof Sandy Yang Sergey Kisselev Shiraz Bheda Sivan Reytan-Miron Tze Y. Lim Anna Jamry-Dziurla Francesca Lugani Jun Y. Zhang Maddalena Marasà Victoria Kolupaeva Emily Groopman Gina Jin Iman Ghavami K Stevens Arielle C. Coughlin Byum Hee Kil Debanjana Chatterjee Drew Bradbury Jason Zheng Karla Mehl Maria M. Morban Rachel Reingold Stacy Piva Xueru Mu Adele Mittrori Agnieszka Szmigielska Aleksandra Gliwińska Andrea Ranghino Andrew S. Bomback Andrzej Badeński Anna Latos‐Bieleńska Anna Materna‐Kiryluk Antonio Amoroso Claudia Izzi Claudio La Scola David J. Cohen Domenico Santoro Dorota Drożdż Enrico Fiaccadori Fangming Lin Francesco Scolari Francesco Tondolo Gaetano La Manna Gerald B. Appel Gian Marco Ghiggeri Gianluigi Zaza Giovanni Montini Giuseppe Masnata Grażyna G Krzemień Isabella Pisani Jai Radhakrishnan Katarzyna Zachwieja Lucía Monaco Loreto Gesualdo Luigi Biancone Luisa Murer Małgorzata Mizerska-Wasiak Marcin Tkaczyk Marcin Zaniew Maria Katarzyna Borszewska-Kornacka Tomasz Szczepański Marijan Saraga Maya K. Rao Monica Bodria Monika Miklaszewska Natalie Uy Olga Baraldi Omar Bjanid Pasquale Esposito Pasquale Zamboli Pierluigi Marzuillo Pietro A. Canetta Przemysław Sikora Rik Westland Russell J. Crew Shumyle Alam Stefano Guarino Susanna Negrisolo Thomas Hays Valeria Grandinetti Velibor Tasić Vladimir J. Lozanovski Yaşar Çalışkan David B. Goldstein

Abstract Kidney anomalies (KA) are developmental disorders that commonly cause pediatric chronic kidney disease and mortality. We examined rare coding variants in 248 KA trios 1,742 singleton cases compared them to 22,258 controls. Diagnostic candidate diagnostic were detected 14.1% of cases. a significant enrichment damaging constrained genes expressed during development associated with other disorders, suggesting phenotype expansion. Consistent these data, 18% patients had...

10.1101/2024.11.05.24316672 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-11-06

Abstract In yeast, actin cables are F-actin bundles that essential for cell division through their function as tracks cargo movement from mother to daughter cell. Actin also affect yeast lifespan by promoting transport and inheritance of higher-functioning mitochondria cells. Here, we report cable stability declines with age. Our genome-wide screen genes identified the open reading frame YKL075C . Deletion results in increases abundance, mitochondrial fitness, replicative lifespan....

10.1101/2021.10.07.463535 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-10-07

ABSTRACT Purpose Soft drusen and subretinal drusenoid deposits (SDD) aka reticular macular disease (RMD) characterize two pathways to advanced age-related degeneration (AMD). We propose these are distinct diseases, with genetic risks, serum risks associated systemic diseases. Methods 126 Subjects AMD had: retinal imaging for RMD status, testing, histories of cardiovascular (CVD) stroke. Results 62 subjects had RMD, 64 were nonRMD (drusen only), 51 CVD or Stroke. correlated significantly...

10.1101/2021.09.27.21263712 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-09-29

<h3>Introduction/Background</h3> Prior studies have demonstrated decreased rates of cervical cancer (CC) screening during the height COVID-19 pandemic. Delayed CC and management may increase incidence mortality. This study examines impact pandemic on guideline-indicated colposcopy. <h3>Methodology</h3> used retrospective data from a large, urban, academic institution-based clinic comprised publicly-insured patients. Patients were non-pregnant, 21 to 65 years old without HIV or other...

10.1136/ijgc-2022-esgo.803 article EN 2022-10-01
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