Iván Chivite
A5042051995- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- HIV, Drug Use, Sexual Risk
- HIV-related health complications and treatments
- COVID-19 Impact on Reproduction
- COVID-19 Clinical Research Studies
- Sex work and related issues
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis C virus research
- COVID-19 and healthcare impacts
- Pharmacological Effects and Toxicity Studies
- Patient Satisfaction in Healthcare
- Genital Health and Disease
- Liver Disease and Transplantation
- Viral Infections and Outbreaks Research
- Intensive Care Unit Cognitive Disorders
- Hepatitis B Virus Studies
- Drug-Induced Adverse Reactions
- LGBTQ Health, Identity, and Policy
- Epilepsy research and treatment
- Syphilis Diagnosis and Treatment
- Reproductive tract infections research
- Streptococcal Infections and Treatments
- Urinary Tract Infections Management
Hospital Clínic de Barcelona
2021-2024
Universitat de Barcelona
2021-2024
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2021-2024
Fundació Clínic per a la Recerca Biomèdica
2023-2024
Fundació de Recerca Clínic Barcelona-Institut d’Investigacions Biomèdiques August Pi i Sunyer
2023
Hospital for Tropical Diseases
2022
Hospital de Sant Joan Despí Moisès Broggi
2020-2021
Agència de Qualitat i Avaluació Sanitàries de Catalunya
2021
BackgroundFactors affecting outcomes of SARS-CoV-2 infection in people living with HIV are unclear. We assessed the factors associated diagnosis and severe among HIV.MethodsWe did a retrospective cohort study using data from PISCIS Catalonia (Spain) between March 1 Dec 15, 2020. linked integrated health-care, clinical, surveillance registries through Public Data Analysis for Health Research Innovation Program (PADRIS) to obtain on diagnosis, chronic comorbidities, as well clinical mortality...
The use of bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) is mainly based on robust, pivotal clinical trials.To provide data BIC/FTC/TAF in real life.This was an observational, retrospective and single-centre study. We included all adult, treatment-naive (TN) treatment-experienced (TE) people living with HIV (PLWH) starting from 8 June 2018. evaluated effectiveness [on treatment (OT), modified intention-to-treat (mITT) (ITT)], tolerability safety those patients who reached 6...
To determine the health status, exercise capacity, and related quality of life (HRQoL) COVID-19 associated acute respiratory distress syndrome (ARDS) survivors, 8 months after diagnosis.All eligible patients were interviewed underwent a physical examination, chest X-ray, 6 min walk test (6MWT). Scales to evaluate post-traumatic stress disorder, depression, anxiety, HRQoL applied.Of 1295 patients, 365 suffered ARDS 166 survived hospital discharge. Five died discharge 48 lost follow-up. Of 113...
Journal Article Cohort Profile: PISCIS, a population-based cohort of people living with HIV in Catalonia and Balearic Islands Get access Andreu Bruguera, Bruguera Centre Epidemiological Studies STI HIV/AIDS (CEEISCAT), Department Health, Generalitat de Catalunya, Badalona, SpainInstitute for Health Science Research Germans Trias i Pujol (IGTP), SpainCIBER Epidemiologia y Salud Pública (CIBERESP), Madrid, Spain https://orcid.org/0000-0002-7524-0768 Search other works by this author on: Oxford...
Reports on the impact of some antiretrovirals against SARS-CoV-2 infection and disease severity are conflicting.We evaluated effect tenofovir as either alafenamide/emtricitabine (TAF/FTC) or disoproxil fumarate/emtricitabine (TDF/FTC) associated clinical outcomes among people living with HIV (PLWH).We conducted a propensity score-matched analysis in prospective PISCIS cohort PLWH (n = 14 978) Catalonia, Spain. We used adjusted Cox regression models to assess association between...
Objective: To assess the impact of coronavirus disease 2019 (COVID-19) epidemics on prevention and care for HIV other sexually transmitted infections at a major reference centre providing preventive clinical services in Catalonia, Spain. Design: We retrospectively compared anonymized laboratory data from March to December 2020 vs. 2019. Methods: Monthly preexposure postexposure prophylaxis users adults with infection were retrieved administrative hospital database. tests HIV, hepatitis B C,...
Pre-exposure prophylaxis (PrEP) is a biomedical intervention that has demonstrated efficacy in HIV prevention individuals at high-risk, among them chemsex users. Out of 190 PrEP users followed Hospital Clinic Barcelona until October 2020, 89% reported drug use, and 63% disclosed they had engaged practices, initiated 64% cases within the past year. Twenty-one percent used 3 or more drugs simultaneously, being GHB/GBL, nitrites, sildenafil, methamphetamine most prevalent combination. Eight...
People living with HIV (PLWH) who engaged in chemsex are at risk of potential drug-drug interactions (pDDIs) recreational drugs. This study aimed to characterize pDDIs between antiretroviral treatment (ART) and drugs evaluate their association unscheduled relevant hospital consultations. We conducted a single-center, retrospective, observational series gay, bisexual, other men have sex (gbMSM) attended tertiary Barcelona, Spain, from February 2018 through August 2019. Associations all...
Abstract Background The use of dolutegravir/lamivudine is based on solid clinical trials; however, real-world data remain limited. Objectives To provide the and effectiveness in persons with HIV a scenario. Patients methods Retrospective, single-centre observational study. We included all adults starting since November 2014. reported demographic, virological immunological variables at baseline assessed [on treatment (OT), modified ITT (mITT) those who reached 6 12 month follow-ups (M6 M12)....
To assess the clinical and immunovirological outcomes among naive patients with advanced HIV presentation starting an antiretroviral regimen in real-life settings.This was a multicentre, prospective cohort study. We included all treatment-naive adults disease (CD4+ T cell count < 200 cells/mm3or presence of AIDS-defining illness) who started therapy between 2010 2020. The main were mortality, virological effectiveness (percentage viral load ≤50 copies/mL) immune restoration CD4+ above 350...
Rapid initiation of ART after HIV diagnosis is recommended for individual and public health benefits. However, certain clinical ART-related considerations hinder immediate therapy.
Liver steatosis (LS) and liver fibrosis (LF) can increase the risk of cardiovascular disease in people with HIV, but their prevalence associated factors are poorly understood. This study aimed to assess LS LF a large cohort HIV.
The pharmacokinetics of bictegravir (BIC) and its association with the decay human immunodeficiency virus (HIV)-1 RNA in genital fluids rectum have not yet been addressed.
People living with HIV who are lost to follow-up have a greater risk of health deterioration, mortality, and community transmission.Our aim was analyse both how rates loss (LTFU) changed between 2006 2020 the COVID-19 pandemic affected these in PISCIS cohort study Catalonia Balearic Islands.We analysed socio-demographic clinical characteristics LTFU yearly adjusted odds ratios assess impact determinants on (the year COVID-19). We used latent class analysis categorize classes based their at...
There are no data on community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections in the context of chemsex phenomenon. This study aimed to characterize CA-MRSA-related a cohort people living with HIV (PLWH) who engage chemsex. At Hospital Clinic Barcelona, from February 2018 January 2022, we analyzed CA-MRSA diagnosed PLWH Epidemiological, behavioral and clinical variables were assessed. Mass spectrometry identification antimicrobial susceptibility testing performed...
Pre-exposure prophylaxis (PrEP) is effective for HIV prevention, but the PrEP care continuum also involves improving awareness, uptake, adherence, and retention in care. Users' awareness often compromised because of vulnerability factors risk behaviors, such as chemsex practice or specific substance use, which could lead to compensation. Correct adherence are essential achieve full effectiveness PrEP. This study describes changes users' behaviors sexually transmitted infections (STIs), well...
Abstract Background While both the burden of therapy and individual drugs in bictegravir/tenofovir alafenamide/emtricitabine (BIC/TAF/FTC) dolutegravir/lamivudine differ, it is unclear whether their real-life tolerability may be also different. Methods Single-centre, clinical cohort analysis all virologically suppressed persons with HIV (PWH) who were first prescribed bictegravir as BIC/TAF/FTC or dolutegravir had taken ≥1 dose study medication. Major outcomes discontinuations either for any...
Pre-Exposure Prophylaxis (PrEP) is a biomedical intervention to prevent HIV infection in seronegative people at high risk of becoming infected. This strategy was endorsed October 2019 by the Spanish Ministry Health.
Background Around 57,000 people in Spain and Portugal currently living with HIV or chronic hepatitis C are unaware of their infection. The COVID-19 pandemic severely disrupted screening efforts for these infections. We designed an intervention to increase sustain opportunistic blood-borne virus (BBV) linkage care (SLTC) by implementing the TEST model. Methods Plan Do Study Act (PDSA) method quality improvement (QI) was implemented 8 healthcare organizations (HCOs), including four hospitals,...
People lost to follow-up (LTFU) from HIV care have an increased risk of worse health. The objective this study is create and validate a score predict LTFU among PLWH in Catalonia the Balearic Islands.