A5033212842- Electromagnetic Fields and Biological Effects
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- COVID-19 and Mental Health
- Folate and B Vitamins Research
- Long-Term Effects of COVID-19
- Hormonal Regulation and Hypertension
- Cancer, Hypoxia, and Metabolism
- Healthcare Systems and Practices
- Metabolomics and Mass Spectrometry Studies
- Mitochondrial Function and Pathology
- Cardiac Valve Diseases and Treatments
- Historical Studies and Socio-cultural Analysis
- Vitamin K Research Studies
- Wireless Body Area Networks
- Pericarditis and Cardiac Tamponade
- Metabolism and Genetic Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 Clinical Research Studies
- Health, Medicine and Society
- Pulmonary Hypertension Research and Treatments
- Systemic Sclerosis and Related Diseases
- Ultrasound and Hyperthermia Applications
- Sexual Differentiation and Disorders
- French Urban and Social Studies
Office of Adolescent Health
2024
University Hospital of Geneva
2012-2023
Geneva College
2022
Ministère de la Santé Publique
2018
Service de Santé des Armées
2006-2013
Fondation pour la Recherche Médicale
2012-2013
Laboratoire de Biologie et Modélisation de la Cellule
2007
Groupe Sociétés, Religions, Laïcités
2005-2007
Hotel Dieu Hospital
2006
Université de Strasbourg
2004
The medium-term impact of the COVID-19 pandemic on wellbeing children and adolescents remains unclear. More than 2 years into pandemic, we aimed to quantify frequency determinants having been severely impacted by estimate its health-related quality life (HRQoL) mental health.
Post-COVID syndrome remains poorly studied in children and adolescents. Here, we aimed to investigate the prevalence risk factors of pediatric post-COVID a population-based sample, stratifying by serological status. Children from SEROCoV-KIDS cohort study (State Geneva, Switzerland), aged 6 months 17 years, were tested for anti-SARS-CoV-2 N antibodies (December 2021-February 2022) parents filled questionnaire on persistent symptoms their (lasting over 12 weeks) compatible with post-COVID. Of...
Background: It has been suggested that oral cobalamin (vitamin B12) therapy may be an effective for treating deficiencies related to food-cobalamin malabsorption. However, the duration of this treatment was not determined. Patients and method: In open-label, nonplacebo study, we studied 30 patients with established deficiency malabsorption, who received between 250 1000 μg crystalline cyanocobalamin per day at least 1 month. Endpoints: Blood counts, serum homocysteine levels were determined...
Transforming growth factor β1 (TGF-β1) has been shown previously to induce striking alterations of bovine adrenocortical cell steroidogenic functions. One the major lesions was characterized as a loss steroid-17α-hydroxylase activity, key step in biosynthetic pathway leading active corticosteroid hormones. The mechanism this negative effect TGF-β1 on differentiated functions investigated. It observed that: 1) 17αhydroxylase activity rapidly decreased cells exposed TGFβ1, time (10–20...
Abstract Background Recently, cases of multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease 2019 (COVID-19) have been reported worldwide. Negative polymerase chain reaction (RT-PCR) testing positive serology most the suggests a postinfectious syndrome. Because pathophysiology this is still poorly understood, extensive virological and immunological investigations are needed. Methods We report series 4 pediatric patients admitted to Geneva University...
Children and adolescents are highly vulnerable to the impact of sustained stressors during developmentally sensitive times. We investigated how demographic characteristics intersect with socioeconomic dimensions shape social patterning quality life mental health in children adolescents, two years into COVID-19 pandemic.We used data from prospective SEROCoV-KIDS cohort study living Geneva (Switzerland, 2022). conducted an intersectional Multilevel Analysis Individual Heterogeneity...
Post-COVID-19, or long COVID, has now affected millions of individuals, resulting in fatigue, neurocognitive symptoms, and an impact on daily life. The uncertainty knowledge around this condition, including its overall prevalence, pathophysiology, management, along with the growing numbers created essential need for information disease management. This become even more critical a time abundant online misinformation potential misleading patients health care professionals.The RAFAEL platform...
Pyruvate is located at a crucial crossroad of cellular metabolism between the aerobic and anaerobic pathways. Modulation fate pyruvate, in one direction or another, can be important for adaptative response to hypoxia followed by reoxygenation. This could alter functioning antioxidant system have protective effects against DNA damage induced such stress. Transient alterations pyruvate are observed tumors. advantageous cancer cells stressful conditions. However, effect tumor poorly documented...
This retrospective cohort study deals with the causes of death among 57,000 military personnel who served in French Navy surface vessels and were observed over period 1975–2000. We successively compared mortality rate specific between two groups differing their potential exposure levels to radar. Occupational was defined according on-board workplace (radar control groups). The age-adjusted ratios navy compared. For all death, results showed that 885 deaths radar group 299 occurred (RR = 1.00...
Résumé Cette recherche porte sur la mise en relation du Quotient de développement (QD) nourrissons avec les différents niveaux dysfonctionnements éducatifs leur famille. Le test utilisé, le Brunet-Lézine, a été proposé au cours visites à domicile, ce qui permis d’observer effets cette passation dynamique familiale. QD, considéré comme un marqueur fiable risque pour l’enfant, est abaissé manière significative dans familles plus désorganisées. Dans moins désorganisées, c’est essentiellement QD...
An in vivo setup for pulsed electric field exposure at 3 GHz is proposed and characterized this work. The system allows far field, whole-body of six animals placed Plexiglas cages with a circular antenna. Chronic exposures under 18 W incident average power (1-4 kW peak power) acute 56 (4.7 were considered. Numerical experimental dosimetry the allowed accurate calculation specific absorption rate (SAR) distributions various conditions. From rat model numerical simulations, mean SAR values 1.3...