Ki‐Il Lee

ORCID: 0000-0002-2069-7912
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About
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Research Areas
  • Sinusitis and nasal conditions
  • Asthma and respiratory diseases
  • Nasal Surgery and Airway Studies
  • Allergic Rhinitis and Sensitization
  • Head and Neck Surgical Oncology
  • Olfactory and Sensory Function Studies
  • Obstructive Sleep Apnea Research
  • Oral and Maxillofacial Pathology
  • Reconstructive Facial Surgery Techniques
  • Neuroscience of respiration and sleep
  • COVID-19 diagnosis using AI
  • Vascular Anomalies and Treatments
  • Dermatology and Skin Diseases
  • COVID-19 and Mental Health
  • IgG4-Related and Inflammatory Diseases
  • SARS-CoV-2 and COVID-19 Research
  • Respiratory viral infections research
  • Laser Applications in Dentistry and Medicine
  • Ocular Diseases and Behçet’s Syndrome
  • Pituitary Gland Disorders and Treatments
  • Hearing Loss and Rehabilitation
  • Salivary Gland Tumors Diagnosis and Treatment
  • COVID-19 and healthcare impacts
  • Soft tissue tumors and treatment
  • Vascular Tumors and Angiosarcomas

Konyang University
2019-2025

Dankook University
2008-2020

Kyung Hee University Hospital at Gangdong
2020

Creative Commons
2020

Konyang University Hospital
2020

Korea Electric Power Corporation (South Korea)
2014

Background Exposure to cigarette smoking (CS) is a major risk factor for airway inflammation. However, little known about the effects of CS exposure on eosinophilic rhinosinusitis with nasal polyps (ERSwNPs). Histopathological and molecular studies were performed investigate its using murine model ERSwNPs. Methods Mice assigned one following four groups (n = 8 each group): control group, (CS group), ERSwNP (ERS ERSwNPs exposed + group). changes investigated various stains, including...

10.2500/ajra.2014.28.4055 article EN American Journal of Rhinology and Allergy 2014-05-01

Background and Objectives: Pediatric chronic rhinosinusitis (CRS) significantly affects children’s quality of life learning abilities. This study aimed to evaluate the postoperative outcomes in pediatric patients who underwent functional endoscopic sinus surgery (FESS) for CRS.Methods: A retrospective review was conducted on FESS CRS at 11 university hospitals. The inclusion criteria were under 20 years old with bilateral disease operated between January 2005 December 2021. data collected...

10.18787/jr.2024.00040 article EN Journal of rhinology 2025-03-24

Background & aims Nasal obstruction caused by nasal septal deviation is very bothersome and, therefore, can affect the patient’s emotional state. However, little known about effect of (NSD) on neuropsychiatric aspects patients. Therefore, this study to verify higher incidence anxiety, depression, and migraine in patients diagnosed with NSD compared general populations using big data. Methods This retrospective cohort collected subjects from Korean National Health Insurance Service (NHIS)...

10.1371/journal.pone.0259468 article EN cc-by PLoS ONE 2021-11-04

This study was designed to evaluate the normal development of nasal septum in Koreans using sagittal MRI for valuable clinical information on septal procedures.Two hundred eighty patients who had their whole visualized midline view were selected among 3,904 with brain from January, 2004 December, 2006 at Dankook University Hospital. The a history surgery or trauma excluded. Following parameters are calculated and analyzed: lengths bony cartilage dorsum cartilage-nasal bone overlap, total...

10.3342/ceo.2008.1.1.29 article EN cc-by-nc Clinical and Experimental Otorhinolaryngology 2008-01-01

Cluster analyses on inflammatory markers of chronic rhinosinusitis (CRS) in Asians from multicenter data are lacking. This study aimed to identify the endotypes CRS Koreans and evaluate relationship between clinical parameters.Nasal tissues were obtained patients with controls who underwent surgery. The investigated by measuring interleukin (IL)-5, interferon (IFN)-γ, IL-17A, IL-22, IL-1β, IL-6, IL-8, matrix metalloproteinase-9, eotaxin-3, eosinophil cationic protein, myeloperoxidase (MPO),...

10.4168/aair.2023.15.4.437 article EN Allergy Asthma and Immunology Research 2023-01-01

Little is known about alternative treatment options for rhinosinusitis (RS). We aimed to evaluate the efficacy of low-level laser therapy (LLLT) RS in experimentally induced rabbit models RS. A total 18 rabbits were divided into four groups: a negative control group (n = 3), an without 5, positive group), with natural recovery and irradiation laser-treated group). Computed tomography histopathological staining performed each group. mRNA protein expression levels local cytokines (IFN-γ,...

10.3390/ijms24010760 article EN International Journal of Molecular Sciences 2023-01-01

In Korea, tree pollens are known to be prevalent in spring, grass summer and weed autumn. However, few studies have revealed their seasonal specificity for allergic rhinitis symptoms. An ARIA (Allergic Rhinitis its Impact on Asthma) classification of was recently introduced clinical validation has not been well proved. The aim this study evaluate the allergens validate with conventional perennial (SAR/PAR) classification.Two hundred twenty six patients were included study. classified...

10.4168/aair.2013.5.2.75 article EN Allergy Asthma and Immunology Research 2013-01-01

Limited information is available regarding strain-related differences in mouse models of allergic rhinitis induced by Dermatophagoides farinae (Der f1). In this study, we compared between two strains and determined the optimal dose Der f1 for models.Forty-eight mice were assigned to following six groups (n=8 per group): group A (control, BALB/c), B f1-sensitized BALB/c, 25 µg), C 100 D C57BL/6), E C57BL/6, F µg). Allergic inflammation was with alum sensitization, followed an intranasal...

10.21053/ceo.2019.01837 article EN cc-by-nc Clinical and Experimental Otorhinolaryngology 2020-05-14

Tobacco smoking (TS) has been known as one of the most potent risk factors for airway inflammatory diseases. However, there a paucity information regarding immunologic alteration mediated by TS in patients with chronic rhinosinusitis nasal polyps (CRSwNP). To identify effect TS, we harvested human tissue samples (never smoker: n=41, current n=22, quitter: n=23) and analyzed expression epithelial-derived cytokines (EDCs) such IL-25, IL-33, thymic stromal lymphopoietin. The expressions Th2...

10.4110/in.2022.22.e35 article EN Immune Network 2022-01-01

Limited understanding exists regarding clinical distinctions between influenza A/H3N2 and A/H1N1 subtypes, particularly in primary health care. We conducted a comparative analysis of symptomatic characteristics subtypes Korea. This retrospective study analyzed medical records patients who presented with positive test results for influenza-like illness (rapid diagnostic test; RIDT) during the H3N2-dominant 2016-2017 H1N1-dominant 2018-2019 seasons. Symptomatic manifestations, contact history,...

10.3390/jcm12175651 article EN Journal of Clinical Medicine 2023-08-30

Obstructive sleep apnea (OSA) is characterized by recurrent occurrences of partial or complete collapse the upper airway during sleep, leading to shallow breathing pauses. These repeated disruptions can result in intermittent hypoxia, hypercapnia, hyperactivity sympathetic nervous system, and fragmented patterns. Left untreated, OSA have significant health implications, including various symptoms serious consequences. Positional a subtype where severity events significantly higher supine...

10.17241/smr.2023.01837 article EN cc-by-nc-nd Sleep Medicine Research 2023-09-30

Objectives Predicting the need for surgical treatment among patients with chronic rhinosinusitis (CRS) is challenging. The delta neutrophil index (DNI) has been proposed as a useful laboratory marker of immature granulocytes, which indicates infection or severe inflammation in several diseases. This study evaluated DNI an early predictor surgery CRS. Methods A total 117 diagnosed CRS were enrolled this retrospective and observational study. Medical records, including symptoms data, WBC...

10.1177/01455613211058491 article EN cc-by-nc Ear Nose & Throat Journal 2021-11-24

Abstract Most patients who undergo open rhinoseptoplasty do not develop any wound at the transcolumellar incision site. However, some require care immediately post-operation. Dressing is difficult to perform in columellar region because of location. Here, we report 2 cases as a complication rhinoseptoplasty. A patient developed mild dehiscence after primary rhinoseptoplasty, whereas another partial skin necrosis revision operation. We applied DuoDERM Extra Thin dressing (ConvaTec Group,...

10.1097/scs.0000000000006782 article EN cc-by-nc-nd Journal of Craniofacial Surgery 2020-09-08

We analyzed the relationship between chronic rhinosinusitis (CRS) and incidence of head neck cancers (HNCs) in a Korean adult population. This retrospective cohort study included data from National Health Insurance Service database. Adjustments were made to minimize risk variables for sex, age, diabetes, hypertension, dyslipidemia, rhinitis two groups. The primary endpoint was newly diagnosed HNC January 2009 December 2018. Among 1,337,120 subjects database, 324,774 with CRS (CRS group)...

10.3390/jcm11185316 article EN Journal of Clinical Medicine 2022-09-09

The novel SARS-CoV-2 virus that causes COVID-19 has emerged rapidly and the caused a global pandemic since it was first diagnosed in December 2019. is seventh associated with human transmission among corona viruses. Otorhinolaryngologists could be vulnerable to this viral due high load nasal cavity nasopharynx. Hence, essential understand from perspective of otorhinolaryngologists. We provide literature reviews previous coronaviruses clinical hallmarks, diagnostic approaches, possible...

10.18787/jr.2020.00321 article EN cc-by-nc Journal of rhinology 2020-08-14

Pleomorphic adenoma (PA) is a benign tumor characterized by slow-growing mixed tumors in the craniofacial area. It relatively common salivary glands; however, PA of nasal cavity, which arises minor glands, rare. We present case large cavity an adult immunocompetent woman with obstruction and intermittent epistaxis. Based on preoperative radiologic examinations, she was misdiagnosed inverted papilloma. Endoscopic resection performed under general anesthesia. Pathologically, patient confirmed...

10.1097/scs.0000000000009646 article EN Journal of Craniofacial Surgery 2023-08-28

Recently, air pollution has become more and severe globally decreased the quality of life significantly in subjects with or without allergic diseases. Air severely affects patients diseases, including rhinitis (AR); therefore, it could devastate life. Many epidemiological studies have shown that pollutants increased outpatient clinic visits as well prevalence/severity AR AR. Traffic-related also increases severity occurrence rate AR, heavy traffic is associated an prevalence...

10.4168/aard.2021.9.1.3 article EN Allergy Asthma & Respiratory Disease 2021-01-01

Vascular leiomyoma (VL) is a rare tumor, particularly in the sinonasal region.The etiology of VL unclear and there are number theories regarding how develops.To date, approximately 20 cases have been reported area.This first case right nasal floor.We present an adult patient with mild obstruction discomfort.Preoperative examination failed to accurately diagnose VL.Transnasal endoscopic resection was performed.There were no complications or recurrence postoperatively.

10.18787/jr.2019.26.2.132 article EN cc-by-nc Journal of rhinology 2019-01-01

Otorhinolaryngologic symptoms such as cough, rhinorrhea, anosmia, ageusia, and fever can precede development of COVID-19. Otolaryngologists are vulnerable to potential COVID-19 infection because early cases have been asymptomatic or show mild manifestations. should wear adequate personal protective equipment (PPE) according location situation. PPE includes medical masks, goggles, fluid-resistant gown gloves. Authors provide clinical recommendations based on for otorhinolaryngologists during...

10.18787/jr.2020.00322 article EN cc-by-nc Journal of rhinology 2020-07-15

Several articles were reported about orbital and nasal involvement of disseminated herpes zoster (DHZ) such as ophthalmicus Hutchinson's sign. In contrast, there is a lack information DHZ accompanied by in elderly immunocompetent patient mucosal change healing period. We experienced an 71-year-old female who was misdiagnosed with preseptal cellulitis initially. The swollen mucosa noticed endoscopically initial CT revealed the mild soft tissue density left maxillary ethmoid sinus...

10.1016/j.xocr.2020.100245 article EN cc-by-nc-nd Otolaryngology Case Reports 2020-11-01
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