A5100709313- Burn Injury Management and Outcomes
- Wound Healing and Treatments
- Cardiac Arrest and Resuscitation
- Injury Epidemiology and Prevention
- Immune Response and Inflammation
- Vascular Anomalies and Treatments
- Hepatitis B Virus Studies
- Cell Adhesion Molecules Research
- Corneal Surgery and Treatments
- Tracheal and airway disorders
- Dermatologic Treatments and Research
- China's Ethnic Minorities and Relations
- Pressure Ulcer Prevention and Management
- Sinusitis and nasal conditions
- Thermal Regulation in Medicine
- Autophagy in Disease and Therapy
- Respiratory Support and Mechanisms
- Pediatric Pain Management Techniques
- Endoplasmic Reticulum Stress and Disease
- Vibrio bacteria research studies
- Sepsis Diagnosis and Treatment
- Blood properties and coagulation
- Migraine and Headache Studies
- Cerebrovascular and genetic disorders
- Cancer Research and Treatments
Qingdao University
2025
Affiliated Hospital of Qingdao University
2025
Chinese PLA General Hospital
2021
Second Military Medical University
2009-2020
Changhai Hospital
2009-2020
Affiliated Hospital of Hebei University
2015
Jilin University
2012-2014
First Hospital of Jilin University
2014
The Military General Hospital of Beijing PLA
2011
In this study, we used human amniotic membrane (AM) to prepare a dermal scaffold with intact basement (BM) and good biostability for quick expansion transplantation of epidermal keratinocytes (EKs). Fresh AM was treated by repeated freeze-thaw cycles DNase digestion. This new method able cleanse the cell components effectively retain BM structure continuous distributions laminin, collagen IV, VI, VII. Subsequently, acellular (AAM) cross-linked 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide...
The purpose of this study was to evaluate burn-related variations inflammation and immunity. Fifty-five mice were divided randomly into sham burn groups. Eighty-seven hospitalized patients also reviewed. In mice, neutrophils monocytes elevated significantly on post day (PBD 1). Lymphocytes reduced PBDs 1 3. Levels serum tumor necrosis factor-α interleukin-6 highest PBD 1. Interleukin-1β levels the On 3, CD4CD25T regulatory cells/CD4 cells in spleen higher. 1, 7, 14, percentage splenic...
Ever since the introduction of invasive hemodynamic monitoring to major burn care, its utility remains controversial. Besides complications, as a guideline for shock resuscitation is often associated with significant excessive fluid burden. This study was summarize clinical experiences noninvasive esophageal echo-Doppler (ED) in and discuss significance variables assessment therapeutic goal.Twenty-one patients an average total body surface area 78.86% +/- 7.75% (62-92%) enrolled this...
Abstract Background Procedural burn pain is the most intense acute and likely type of injury to be undertreated due physician’s fear adverse effect analgesia lack anesthetist present. At our institution, in cases, local detersion debridement were performed at ward level without any analgesics. This article describes a study designed test fixed nitrous oxide/oxygen mixture on dressing pain. Methods/design The experiment was carried out three centers. patients given number from 1 240. A...
To investigate early hemodynamics of severely burned patients via PiCCO and to discuss clinical significance hemodynamic monitoring for burn shock resuscitation, 55 extensive were enrolled in this retrospective study. The fluid resuscitation was guided according Chinese General Formula adjusted with urinary output 0.5–1.0 ml/h/kg as a goal. All diagnosed within relatively stable condition during stage, they received 6 hours after burn. preload parameter intrathoracic blood volume index low...
Rapid repair of vascular injury is an important prognostic factor for electrical burns. This achieved mainly via stromal cell-derived (SDF)-1α promoting the mobilization, chemotaxis, homing, and targeted differentiation bone marrow mesenchymal stem cells (BMSCs) into endothelial cells. Forming a concentration gradient from site local damage in circulation essential to role SDF-1α. In previous study, we developed reactive oxygen species (ROS)-sensitive PPADT nanoparticles containing SDF-1α...
Uncontrolled inflammatory cytokine production by macrophages contributes to numerous conditions, including infection, endotoxemia and sepsis. A previous study proposed that endoplasmic reticulum (ER) stress acts as an essential process in macrophages. The present used a mouse sepsis model <em>in vitro</em> demonstrate homeodomain‑interacting protein kinase 2 (HIPK2) sustained ER stress‑dependent manner. HIPK2 expression was upregulated the early phase of lipopolysaccharide...
Hemiplegic migraine is a rare variation of with aura (MA) which should be classified as either familial hemiplegic (FHM) or sporadic (SHM) [1]. SHM defined attacks associated some degree motor weakness/hemiparesis during the phase and no first relative (parent, sibling child) has identical attacks. FHM only subtype for monogenic mode inheritance (autosomal dominant) been clearly established to caused by mutations in any following three gene loci—CACNA1A, ATP1A2 SCN 1A [2, 3]. Some recent...
Objective: To explore the preferred test to screen for pulmonary arteriovenous malformations (PAVMs) and predict probability of interventional embolization. Methods: We performed a retrospective observational study evaluating patients with idiopathic PAVMs from 2009 2019. After clinical evaluation, total 105 were studied, including 71 positive digital subtraction angiography (DSPA) findings 34 negative DSPA findings. The following patient data assessed: blood test, chest radiograph,...
Objective To investigate the molecular mechanism of silencing Tumor necrosis factorα inducing protein 3 (A20) and receptor-interacting (RIP) gene promoting tumor factorrelated apoptosis-inducing ligand (TRAIL)-induced apoptosis in hepatocellular carcinoma cell lines.Methods Synthesized A20-small interfering RNA (siRNA) RIP-siRNA were transfected into HepG2 cells.The death was determined by acid phosphatase assay expression Caspase-8 Western blotting after A20-siRNA or combined with TRAIL...