A5054999797- Cardiac Arrest and Resuscitation
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Disease and Adiposity
- Mechanical Circulatory Support Devices
- Coronary Interventions and Diagnostics
- Lipoproteins and Cardiovascular Health
- Cardiac Ischemia and Reperfusion
- Cardiac Fibrosis and Remodeling
- Machine Learning and Data Classification
- Cardiovascular Function and Risk Factors
- Trauma and Emergency Care Studies
- Cancer, Lipids, and Metabolism
- Disaster Response and Management
- Cardiac Structural Anomalies and Repair
- Data Mining Algorithms and Applications
- Clusterin in disease pathology
- Heart Failure Treatment and Management
- Cardiac electrophysiology and arrhythmias
- Lipid metabolism and disorders
- Pancreatic and Hepatic Oncology Research
- Respiratory Support and Mechanisms
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Heart Rate Variability and Autonomic Control
- Diabetes, Cardiovascular Risks, and Lipoproteins
Hirosaki University
2013-2024
Hirosaki University Hospital
2022-2024
RIKEN Center for Advanced Intelligence Project
2020-2023
RIKEN
2020-2022
Weatherford College
2021
Japanese Circulation Society
2011-2021
Aomori Prefectural Central Hospital
2015-2021
Nagoya Institute of Technology
2016-2018
Osaka University Hospital
2005-2017
The University of Tokyo
2015
To elucidate the relevance of gut dysbiosis in Parkinson's disease (PD) progression, we made random forest models to predict progression PD two years by microbiota 165 patients. The area under receiver operating characteristic curves (AUROCs) microbiota-based for Hoehn & Yahr (HY) stages 1 and 2 were 0.799 0.705, respectively. Similarly, predicted Movement Disorder Society-Unified Disease Rating Scale (MDS-UPDRS) III scores an early stage with AUROC = 0.728. Decreases short-chain fatty...
Allopurinol, an inhibitor of xanthine oxidase, was shown to improve the regional ventricular function after coronary artery occlusion and reperfusion in animal models. The effects oral administration allopurinol on a transient increase free radical generation primary percutaneous transluminal angioplasty (PTCA) patients with acute myocardial infarction (AMI) their clinical outcomes were examined. Thirty-eight AMI undergoing PTCA randomly assigned control (group 1, n = 20) treatment groups 2,...
There are few reports examining regional differences between rural prefectures and metropolitan areas in the management of acute myocardial infarction (AMI) Japan.Methods Results:In Rural AMI registry, a prospective, multi-prefectural registry 4 (Ishikawa, Aomori, Ehime Mie), total 1,695 consecutive patients were registered 2013. Among them, 1,313 who underwent primary percutaneous coronary intervention (PPCI) within 24 h onset enrolled this study (Rural group), compared with cohort data...
(1) Background: This study aimed to evaluate the effectiveness of using a pre-existing video on CPR support preclinical resuscitation education for medical students; (2) Methods: In total, 129 students selected learn YouTube or conventional screencast by their university faculties. All responded pre- and post-training multiple-choice questionnaire basic knowledge CPR, and, based responses, an analysis covariance (ANCOVA) was conducted assess comparability across learning modalities. (3)...
Coreset selection, which involves selecting a small subset from an existing training dataset, is approach to reducing data, and various approaches have been proposed for this method. In practical situations where these methods are employed, it often the case that data distributions differ between development phase deployment phase, with latter being unknown. Thus, challenging select effective of performs well across all scenarios. We therefore propose Distributionally Robust Selection...
We propose Duality Gap KIP (DGKIP), an extension of the Kernel Inducing Points (KIP) method for dataset distillation. While existing distillation methods often rely on bi-level optimization, DGKIP eliminates need such optimization by leveraging duality theory in convex programming. The has been introduced as a way to avoid optimization; however, it is limited squared loss and does not support other functions (e.g., cross-entropy or hinge loss) that are more suitable classification tasks....
High-Sensitivity cTn to Rule-In and Rule-Out NSTEMI ••••
Cutting-edge technologies such as genome editing and synthetic biology allow us to produce novel foods functional proteins. However, their toxicity allergenicity must be accurately evaluated. It is known that specific amino acid sequences in proteins make some allergic, but many of these remain uncharacterized. In this study, we introduce a data-driven approach machine-learning method find undiscovered allergen-specific patterns (ASPs) among sequences. The proposed enables an exhaustive...
Background In an animal model of acute myocardial infarction (AMI), deletion matrix metalloproteinase (MMP)-9 results in suppression the development cardiac rupture. The present study sought to clarify how MMP-9 activity is related pathophysiologies AMI and rupture humans. Methods Results Levels interleukin-8 (IL-8), polymorphonuclear leukocyte (PMN) elastase, monocyte chemotactic protein-1 (MCP-1) MMP were measured pericardial fluid obtained from 28 patients with angina pectoris (AP group)...
Inflammation caused by activated macrophages and T lymphocytes may trigger plaque rapture in acute coronary syndrome (ACS). Anandamide 2-arachidonylglycerol (2-AG) are macrophage-derived signal lipids be involved the pathogenesis of ACS, but no clinical relevant data have been reported. In 43 myocardial infarction (AMI) patients (66 ± 2 years), blood samples were obtained from aortic root infarct-related artery (IRA) using a PercuSurge system during primary percutaneous intervention (PCI)....
The morbidity of cardiovascular disease in patients with type 2 diabetes mellitus (DM) deteriorates combination dyslipidemia. accumulation remnant lipoproteins fasting and postprandial hypertriglyceridemia is highly atherogenic. current study investigated whether the dipeptidyl peptidase-4 inhibitor sitagliptin ameliorates dyslipidemia hyperglycemia.We enrolled 38 DM (20 males 18 females, 65.7±9.9 years old, HbA1c levels ＜8.4%), all gave written informed consent. Sitagliptin (50 mg/day) was...
This study examined the clinical significance of regenerating islet-derived family member 4 (REGIV) in surgically resected gastric tumors. The potential REGIV as a biomarker cancer was also assessed including its predictive value for prognosis and recurrence after surgery.Immunohistochemistry performed to assess expression status specimens. quantitative genetic diagnostic method, transcription-reverse transcription concerted reaction (TRC) that targeted mRNA applied prediction peritoneal...