Junwei Guo

ORCID: 0000-0002-2203-0070
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About
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Research Areas
  • Robotics and Sensor-Based Localization
  • Virus-based gene therapy research
  • Advanced Vision and Imaging
  • RNA Interference and Gene Delivery
  • Advanced Image and Video Retrieval Techniques
  • Bone Metabolism and Diseases
  • Heat shock proteins research
  • 3D Surveying and Cultural Heritage
  • Hepatitis B Virus Studies
  • RNA modifications and cancer
  • Optical measurement and interference techniques
  • Electrochemical Analysis and Applications
  • Augmented Reality Applications
  • Viral Infectious Diseases and Gene Expression in Insects
  • Physiological and biochemical adaptations
  • Ferroptosis and cancer prognosis
  • Bone health and treatments
  • TGF-β signaling in diseases
  • Invertebrate Immune Response Mechanisms
  • Wireless Power Transfer Systems
  • Ubiquitin and proteasome pathways
  • Advanced biosensing and bioanalysis techniques
  • Engineering and Technology Innovations
  • Hand Gesture Recognition Systems
  • Advanced Image Processing Techniques

Dalian Ocean University
2025

Zhejiang Chinese Medical University
2024-2025

Beijing Information Science & Technology University
2024

Beijing Institute of Technology
2008-2023

Zhengzhou Railway Vocational & Technical College
2021

Harbin Institute of Technology
2014-2021

Tsinghua University
2011-2014

Fuzhou University
2011-2014

Xi'an Jiaotong University
2014

Nantes Université
2014

Abstract Differentiation of committed precursor cells into the osteoblast lineage is tightly regulated by several factors, including Runx2 and BMP2. We previously reported that C terminus Hsc70-interacting protein/STIP1 homology U-Box containing protein 1 (CHIP/STUB1) negatively differentiation through promoting degradation. However, how CHIP during remains unknown. In this study, we found miR-764-5p up-expressed in calvarial progenitor cells, coupled with down-expression protein. observed...

10.1002/jbmr.1597 article EN Journal of Bone and Mineral Research 2012-03-09

Abstract Background Hepatocellular carcinoma (HCC) is a prevalent malignant tumor that poses major threat to people’s lives and health. Previous studies have found multiple deubiquitinating enzymes are involved in the pathogenesis of HCC. The purpose this work was elucidate function mechanism enzyme USP40 HCC progression. Methods expression human tissues cell lines investigated using RT-qPCR, western blotting immunohistochemistry (IHC). Both vitro vivo experiments were conducted determine...

10.1186/s13062-024-00456-3 article EN cc-by Biology Direct 2024-02-02

Abstract The spermatogenesis associated 4 gene (Spata4, previously named TSARG2) was demonstrated to participate in spermatogenesis. Here we report that Spata4 is expressed osteoblasts and overexpression of accelerates osteoblast differentiation mineralization MC3T3-E1 cells. We found interacts with p-Erk1/2 the cytoplasm enhances phosphorylation Erk1/2. Intriguingly, observed increases transcriptional activity Runx2, a critical transcription factor regulating differentiation. showed...

10.1002/jbmr.394 article EN Journal of Bone and Mineral Research 2011-03-28

Carboxyl terminus of Hsp70-interacting protein (CHIP or STUB1) is an E3 ligase that regulates the stability several proteins involved in tumor growth and metastasis. However, role CHIP bone remodeling vivo has not been reported. This study was undertaken to investigate mechanism regulation mass remodeling.The phenotype Chip(-/-) mice assessed by histologic, histomorphometric, micro-computed tomographic analyses. The which degradation necrosis factor receptor-associated 6 (TRAF6) inhibition...

10.1002/art.38521 article EN Arthritis & Rheumatology 2014-02-27

Purpose: Whole body hyperthermia (WBH) has been regarded as a promising alternative therapy to cure late stage cancer with metastasis. As the final biological and therapeutic effects are dependent on specific protocol, potential of using microwave-based WBH approach for metastasis inhibition is established its typical results discussed.Materials methods: The effectiveness 30-min whole (WH) animals, raised rectal temperature 40.2° ± 0.3°C 30 min followed by 84 h observation 2450 MHz microwave...

10.3109/02656736.2011.559613 article EN International Journal of Hyperthermia 2011-04-18

Cidofovir (CDV) is an acyclic nucleoside phosphonate analog that shows broad spectrum anti-DNA virus activity. In this study, we have investigated the influence of cidofovir on tumor xenografts derived from HeLa and SiHa cells nude mice. The HeLa/SiHa in mice were established by inoculating subcutaneously. Administration intratumoral injection led to significant reduction. Enhanced protein levels p53 p-pRb within samples observed. Immunohistology analysis sections indicated decreased PCNA...

10.3727/096504010x12704916124909 article EN cc-by-nc-nd Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 2009-11-01

Chronic hepatitis B virus (HBV) infection is an independent risk factor for the development of hepatocellular carcinoma (HCC). The HBV HBx gene frequently identified as integrant in chromosomal DNA patients with HCC. encodes X protein (HBx), a putative viral oncoprotein that affects transcriptional regulation several cellular genes. Therefore, may be ideal target to impede progression infection-related In this study, integrated was transcriptionally downregulated using artificial...

10.1177/1087057112463066 article EN cc-by-nc-nd SLAS DISCOVERY 2012-10-06

Tumor thermotherapy is a method of cancer treatment wherein cells are killed by exposing the body tissues to high temperatures. Successful clinical implementation this requires clear understanding and assessment changes tumor area after therapy. In study, we evaluated effect near-infrared laser at molecular, cellular, physical levels. We used single-walled carbon nanotubes (SWNTs) in combination with thermotherapy. established mouse model for breast randomly divided mice into four groups:...

10.1063/1.4869095 article EN cc-by AIP Advances 2014-03-01

This paper discusses low speed double stator permanent magnet generator design combined with control strategies. The study is based on analytical model. results indicate that structure a compromise between torque volume density, power efficiency and strategy. reactance value presents an important factor for the system selection of work will focus tidal below its rated value. rotational turbine proportional to maximize coefficient. For same speed, loss different when it controlled by An...

10.1109/peac.2014.7037904 article EN International Power Electronics and Application Conference and Exposition 2014-11-01

10.1016/j.elecom.2014.08.025 article EN Electrochemistry Communications 2014-09-05

10.1007/s13198-021-01428-w article EN International Journal of Systems Assurance Engineering and Management 2021-11-13

Abstract the core‐shell particles were prepared by dispersion copolymerization. The characterized with Fourier‐transform infrared spectroscopy, Transmission electron microscope and scanning microscope. stability electrophoretic performance of studied in mixed medium tetrachloroethylene cyclohexance. Microcapsules containing coacervation. Results showed that had good it no electric response, which could be used as grounding for E‐Ink. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 104: 1195–1199,

10.1002/app.25815 article EN Journal of Applied Polymer Science 2007-01-26

This paper presents an algorithm based on the method of supervised machine learning and multi-keyframes to achieve markerless augmented reality (AR) application when there is a locally planar object in scene. The main goal solve problem AR tracking outdoor environment by only using vision natural features. Instead fiducial markers, we track keypoints, during which point correspondences are established from classification perspective. range able be extended employing many reference images....

10.1109/cadcg.2009.5246882 article EN 2009-08-01
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