- Diabetes Management and Research
- Diabetes Treatment and Management
- Neonatal Respiratory Health Research
- Retinopathy of Prematurity Studies
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Cardiac, Anesthesia and Surgical Outcomes
- Birth, Development, and Health
- Acute Myocardial Infarction Research
- Neonatal and fetal brain pathology
- Cardiac pacing and defibrillation studies
- Health disparities and outcomes
- Neonatal Health and Biochemistry
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Infant Nutrition and Health
- Medication Adherence and Compliance
- Potassium and Related Disorders
- Diabetes Management and Education
University of Gothenburg
2019-2025
Swedish Society for Nature Conservation
2022-2025
Sahlgrenska University Hospital
2023-2025
Neuroscience Institute
2020-2024
National Academy of Medicine
2024
Region Västra Götaland
2024
Uddevalla sjukhus
2021
Statistics Sweden
2020
Statisticon (Sweden)
2019
The excess risks of death from any cause and cardiovascular causes among persons with type 2 diabetes various levels glycemic control renal complications are unknown. In this registry-based study, we assessed these according to diabetes.We included patients who were registered in the Swedish National Diabetes Register on or after January 1, 1998. For each patient, five controls randomly selected general population matched age, sex, county. All participants followed until December 31, 2011,...
The excess risk of death from any cause and cardiovascular causes is unknown among patients with type 1 diabetes various levels glycemic control. We conducted a registry-based observational study to determine the according level control in Swedish population diabetes.We included our registered National Diabetes Register after January 1, 1998. For each patient, five controls were randomly selected general matched age, sex, county. Patients followed until December 31, 2011, through for...
<h3>Importance</h3> Lack of arachidonic acid (AA) and docosahexaenoic (DHA) after extremely preterm birth may contribute to morbidity, including retinopathy prematurity (ROP). <h3>Objective</h3> To determine whether enteral supplementation with fatty acids from 40 weeks’ postmenstrual age reduces ROP in infants. <h3>Design, Setting, Participants</h3> The Mega Donna trial, a randomized clinical was multicenter study performed at 3 university hospitals Sweden December 15, 2016, 2019. screening...
Background: In Sweden, FreeStyle Libre a flash glucose monitoring system came onto the market in 2014 as complement to self-monitoring of blood glucose. The aim this study was evaluate accuracy and treatment experience system. Methods: Fifty-eight adults with type 1 diabetes used for 10–14 days measured capillary levels HemoCue measurement at least six times day simultaneously. Results: For entire period, mean absolute relative difference (MARD) 13.2% (95% confidence interval [CI]...
To evaluate if the lowest target level for glycated haemoglobin (HbA1c) of <6.5% is associated with lower risk retinopathy and nephropathy than less tight control in children adults type 1 diabetes.Population based cohort study.Swedish National Diabetes Registry, January 1998 to 31 December 2017.10 398 diabetes followed from diagnosis, or close thereafter, until end 2017.Relative (odds ratios) different mean levels HbA1c.Mean age participants was 14.7 years (43.4% female), duration 1.3...
Abstract Background To examine the incidence of atrial fibrillation in individuals with type 2 diabetes compared age- and sex-matched controls from general population its variation relation to glycaemic control renal function. Methods A total 421,855 patients Swedish National Diabetes Registry 2,131,223 Population Registry, matched for age, sex county, were included followed January 1, 2001 December 31, 2013. Results Overall, 8.9% 7.0% diagnosed during follow-up, unadjusted risk ratio (IRR)...
Heart failure (HF) and non-cardiac comorbidities often coexist are known to have an adverse effect on outcome. However, the prevalence prognostic impact of in patients with HF reduced ejection fraction (HFrEF) vs. those preserved (HFpEF) remain inadequately studied.We used data from Swedish Failure Registry 2000 2012. HFrEF was defined as EF < 50% HFpEF ≥ 50%. Of 31 344 available for analysis, 79.3% (n = 24 856) had 20.7% 6 488) HFpEF. The outcome all-cause mortality. We examined association...
Background: Continuous glucose monitoring (CGM) is a tool widely used in the treatment of patients with type 1 diabetes. The purpose current study was to evaluate whether accuracy and patient satisfaction differ between Enlite™ (Medtronic MiniMed, Inc., Northridge, CA) Dexcom® (San Diego, G4 PLATINUM CGM sensors. Subjects Methods: Thirty-eight ambulatory diabetes Dexcom Enlite sensors simultaneously for minimum 4 maximum 6 days. Patients measured capillary levels HemoCue® (Ängelholm, Sweden)...
To evaluate the long-term use of secondary prevention medications [statins, β-blockers, renin-angiotensin-aldosterone system (RAAS) inhibitors, and platelet inhibitors] after coronary artery bypass grafting (CABG) association between medication mortality.
To prevent blindness, repeated infant eye examinations are performed to detect severe retinopathy of prematurity (ROP), yet only a small fraction those screened need treatment. Early individual risk stratification would improve screening timing and efficiency potentially reduce the blindness.To create validate an easy-to-use prediction model using birth characteristics describe continuous hazard function for ROP treatment.In this retrospective cohort study, Swedish National Patient Registry...
<h3>Importance</h3> Supplementing preterm infants with long-chain polyunsaturated fatty acids (LC-PUFA) has been inconsistent in reducing the severity and incidence of retinopathy prematurity (ROP). Furthermore, few studies have measured long-term serum lipid levels after supplementation. <h3>Objective</h3> To assess whether ROP is associated LC-PUFA, especially docosahexaenoic acid (DHA) arachidonic (AA), during first 28 postnatal days. <h3>Design, Setting, Participants</h3> This cohort...
The excess risk of major coronary events (acute myocardial infarction (AMI) or death from heart disease (CHD)) in individuals with type 1 diabetes (T1D) relation to glycaemic control and renal complications is not known.Individuals T1D the Swedish National Diabetes Registry after January 1998, without a previous MI (n=33 170) 64 698 controls matched on age, sex county were followed respect non-fatal AMI CHD. Data censored at due any cause until 31 December 2011.During median follow-up 8.3...
According to recent guidelines, individuals with type 1 diabetes should spend <4.0% of time per day glucose levels <3.9 mmol/L (<70 mg/dL) and <1.0% <3.0 (<54 mg/dL).In the GOLD randomized crossover trial, 161 treated multiple daily insulin injections (MDI) were continuous monitoring (CGM) or conventional therapy self-monitoring blood (SMBG) evaluated over 16 months. We estimated association between spent in hypoglycemia various mean HbA1c levels.Time (<3.9 mmol/L) increased significantly...
Abstract OBJECTIVES Stroke is a serious complication in patients with acute type A aortic dissection (ATAAD). Previous studies investigating stroke ATAAD have been limited by small cohorts and shown diverging results. We sought to identify risk factors for evaluate the effect of on outcomes surgical patients. METHODS The Nordic Consortium Acute Type Aortic Dissection database included operated at 8 Scandinavian Hospitals between 2005 2014. RESULTS occurred 177 (15.7%) out 1128 Patients...
Abstract Aim To analyse the challenges faced by parents of extremely preterm infants born before 24 weeks gestation and potential buffering effect perceived resources on family's health continuum. Methods The qualitative data were obtained from 70 gestation, through open‐ended questions in a survey. An inductive content analysis was conducted to identify themes patterns parents' experiences. enhance understanding findings, salutogenic theory incorporated contextualise emerging deficits....
ABSTRACT Introduction Retinopathy of prematurity (ROP) is a leading cause preventable childhood blindness. We investigated the association early postnatal low-dose intravenous hydrocortisone used for prevention bronchopulmonary dysplasia (BPD) with ROP-outcome among extremely preterm infants in Swedish cohort. Methods This retrospective cohort study included born before 28 weeks gestational age (GA). Infants September 2020 - August 2022, treated BPD, were compared to untreated controls 2016...
Abstract The socioeconomic burden of hip fractures, the most severe osteoporotic fracture outcome, is increasing and current clinical risk assessment lacks sensitivity. This study aimed to develop a method for improved prediction by incorporating measurements bone microstructure composition derived from high-resolution peripheral quantitative computed tomography (HR-pQCT). In prospective cohort 3028 community-dwelling women aged 75 80, all participants answered questionnaires underwent...
205 Background: To study the compliance in handling investigational medicinal product (IMP) and its impact on outcomes patients with metastatic colorectal cancer participating AGENT trial (NCT03750786). Methods: In a randomized, multicenter, multinational, phase III study, were randomized to receive either arfolitixorin (n=245) or leucovorin 5-fluorouracil (5-FU), oxaliplatin bevacizumab as first-line treatment. Logistic regression was applied for overall response rate (ORR) Cox all-cause...
Abstract Background The early life growth period, from conception to ~2 years of age, has proven crucial for later health. We hypothesized that could explain variations in pubertal and timing, adult height. Methods This retrospective, population-based study was conducted Sweden. A subgroup, including individuals all gestational ages birth sizes ( n = 4700, 50% males), the longitudinal GrowUp 1974&1990 Gothenburg cohorts used. QEPS variables were analyzed univariate multivariate linear...
Glucagon-like peptide 1 receptor agonists (GLP-1RAs) have shown improved symptomatic relieving and functional capacity in patients with heart failure (HF) preserved ejection fraction obesity. The purpose of this study was to evaluate the effect GLP-1RA on outcome HF. A retrospective analysis performed based Swedish HF Registry since 2007 among a body mass index (BMI) >25 kg/m2 assess whether treatment associated reduced mortality In overall cohort, 34,247 were not treated GLP-1RA, 808 were....
It has been suggested that long-term risk for incident cancer is increased in patients operated with cardiopulmonary bypass. We compared the and cancer-specific death between undergoing coronary artery bypass grafting (CABG) without All a history of first-time CABG Sweden during 1997-2020 were included nationwide population-based observational cohort study. Individual patient data from SWEDEHEART registry four other mandatory national registries merged. The incidence new was or using...