A5015052483- Retinopathy of Prematurity Studies
- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Neonatal Health and Biochemistry
- Ophthalmology and Visual Impairment Studies
- Visual perception and processing mechanisms
- Ophthalmology and Eye Disorders
- Retinal Diseases and Treatments
- Retinal Development and Disorders
- Sympathectomy and Hyperhidrosis Treatments
- Birth, Development, and Health
- Photoreceptor and optogenetics research
- Botulinum Toxin and Related Neurological Disorders
- Preterm Birth and Chorioamnionitis
- Intraocular Surgery and Lenses
- Cholinesterase and Neurodegenerative Diseases
- Craniofacial Disorders and Treatments
- Ocular Disorders and Treatments
- Kawasaki Disease and Coronary Complications
- Pregnancy and preeclampsia studies
- Child Abuse and Related Trauma
- Traumatic Brain Injury and Neurovascular Disturbances
- Anesthesia and Pain Management
- Retinal and Optic Conditions
- Cardiovascular Conditions and Treatments
Harvard University
2014-2025
Boston Children's Hospital
2015-2025
Boston Children's Museum
2021
Edward Via College of Osteopathic Medicine
2018
Society of Critical Care Medicine
2009
American Association of Critical-Care Nurses
2009
To assess WINROP (https://winrop.com), an algorithm using postnatal weight measurements, as a tool for the prediction of retinopathy prematurity (ROP) in large geographically and racially diverse study population.WINROP analysis was performed retrospectively on conventionally at-risk infants from 10 neonatal intensive careunits.Weight measurements were entered into WINROP, which signals alarm abnormal gain rate. Infants classified categories no (unlikely to develop type 1ROP)and (at risk...
<h3>Objective</h3> To validate longitudinal postnatal weight gain as a method for predicting severe retinopathy of prematurity (ROP) in US cohort. <h3>Methods</h3> Both ROP evaluations and weekly measurements from birth to postmenstrual week 36 318 infants were entered into computer-based surveillance system, WINROP. This system signaled an alarm when the rate decreased compared with control subjects. Infants classified 3 groups: (1) no alarm, (2) low-risk or (3) high-risk alarm. Maximum...
To evaluate the impact of low birth weight as a risk factor for retinopathy prematurity (ROP) that will require treatment in correlation with gestational age at (GA).In total, 2941 infants born <32 weeks GA were eligible from five cohorts preterm previously collected analysis WINROP (Weight IGF-I Neonatal ROP) following locations: Sweden (EXPRESS) (n = 426), North America 1772), Boston 338), Lund 52), and Gothenburg 353). Data regarding birth, (BW), gender, need ROP retrieved. Birth standard...
To prevent blindness, repeated infant eye examinations are performed to detect severe retinopathy of prematurity (ROP), yet only a small fraction those screened need treatment. Early individual risk stratification would improve screening timing and efficiency potentially reduce the blindness.To create validate an easy-to-use prediction model using birth characteristics describe continuous hazard function for ROP treatment.In this retrospective cohort study, Swedish National Patient Registry...
An elevated threshold for neuroplasticity limits visual gains with treatment of residual amblyopia in older children and adults. Acetylcholinesterase inhibitors (AChEI) can enable promote recovery from adult mice. Motivated by these promising findings, we sought to determine whether donepezil, a commercially available AChEI, adults amblyopia. In this open-label pilot efficacy study, 16 participants (mean age years; range 9-37 years) anisometropic and/or strabismic were treated daily oral...
Objective: To determine the incidence of corneal abrasions in critically ill children requiring neuromuscular blockade (NMB) and to whether a moisture chamber over eye is more effective preventing compared with standard therapy. Design: Randomized controlled clinical trial. Setting: Three pediatric intensive care units at two free-standing, university-affiliated children's hospitals. Patients: Consecutive intubated, mechanically ventilated patients receiving NMB <36 hours, 2 weeks 18 years...
The coronavirus disease 2019 (COVID-19) pandemic has significantly disrupted the delivery of healthcare. Although most nonurgent ophthalmology visits at Boston Children's Hospital were canceled, premature infants risk for retinopathy prematurity (ROP) still required timely, in-person care during initial 3-month period infection surge in Massachusetts. purpose current study was to report our protocols mitigating exposure severe acute respiratory syndrome 2 (SARS-CoV-2) between and eye...
Background/Aims Prematurely born infants undergo costly, stressful eye examinations to uncover the small fraction with retinopathy of prematurity (ROP) that needs treatment prevent blindness. The aim was develop a prediction tool (DIGIROP-Screen) 100% sensitivity and high specificity safely reduce screening those not needing treatment. DIGIROP-Screen compared four other ROP models based on longitudinal weights. Methods Data, including at 24–30 weeks gestational age (GA), for development...
<b><i>Background:</i></b> Retinopathy of prematurity (ROP) is a sight-threatening disease affecting extremely preterm infants. The introduction new ROP screening surveillance systems, with higher sensitivity and specificity than established guidelines, has the potential to reduce number stressful eye examinations in these <b><i>Objectives:</i></b> To improve WINROP (Weight, Insulin-like growth factor-I, Neonatal, ROP) system, identifying...
Objective: To understand the relationship between medication during pregnancy and single live preterm birth of infant in women childbearing age Shaanxi province. Methods: A cross-sectional design was used this study stratified multistage random sampling method used. questionnaire survey conducted childbearing-aged selected through multi stage 2010 to 2013. Qualitative datum described by percentage measurement mean±standard deviation. Logistic regression analysis done evaluate infant....