A5084149772- Retinal Development and Disorders
- Retinal Diseases and Treatments
- Retinopathy of Prematurity Studies
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Retinal and Optic Conditions
- Ocular Oncology and Treatments
- Tissue Engineering and Regenerative Medicine
- Glaucoma and retinal disorders
- Bone Tissue Engineering Materials
- Knee injuries and reconstruction techniques
- Photoreceptor and optogenetics research
- Retinal and Macular Surgery
- Electrospun Nanofibers in Biomedical Applications
- Orthopaedic implants and arthroplasty
- Spine and Intervertebral Disc Pathology
- Periodontal Regeneration and Treatments
- Bone fractures and treatments
- Magnetism in coordination complexes
- Cellular Mechanics and Interactions
- Medical Imaging and Analysis
- Additive Manufacturing and 3D Printing Technologies
- Musculoskeletal pain and rehabilitation
- 3D Printing in Biomedical Research
- Saffron Plant Research Studies
University of Naples Federico II
2004-2025
Policlinico Umberto I
2024
Harvard University
2016-2023
Boston Children's Hospital
2016-2023
Federico II University Hospital
2009-2022
Institute of Polymers, Composites and Biomaterials
2003-2020
University of Cagliari
2010-2020
National Research Council
2020
Agostino Gemelli University Polyclinic
2015
Università Cattolica del Sacro Cuore
2015
Autologous graft is considered the gold standard of materials; however, this approach still limited due to both small amount tissue that can be collected and reduced cell viability cells obtained. The aim preliminary study was demonstrate efficacy an innovative medical device called Rigeneracons® (CE certified Class I) provide autologous micro‐grafts immediately available used in clinical practice. Moreover, instrument able create enriched progenitors which maintain their regenerative...
Objectives . In a previous randomized clinical trial (Falsini et al. (2010)), it was shown that short-term Saffron supplementation improves retinal flicker sensitivity in early age-related macular degeneration (AMD). The aim of this study to evaluate whether the observed functional benefits from may extend over longer follow-up duration. Design Longitudinal, interventional open-label study. Setting Outpatient ophthalmology setting. Participants Twenty-nine AMD patients (age range: 55–85...
To determine whether the functional effects of oral supplementation with Saffron, a natural compound that proved to be neuroprotective in early age-related macular degeneration, are influenced by complement factor H (CFH) and maculopathy susceptibility 2 (ARMS2) risk genotypes. Thirty-three AMD patients, screened for CFH (rs1061170) ARMS2 (rs10490924) polymorphisms receiving Saffron (20 mg/day) over an average period treatment 11 months (range, 6–12), were longitudinally evaluated clinical...
To determine whether the Ganzfeld ERG photopic negative response (PhNR), an assay of inner retinal activity, is altered in childhood optic glioma (OPG).Seventeen pediatric patients with a diagnosis OPG, established on neuro-ophthalmologic and brain/orbit magnetic resonance imaging (MRI) criteria, were enrolled. The examination protocol included determination visual acuity (VA), fundus examination, nerve fiber layer (RNFL) measurement spectral-domain optical coherence tomography (SD-OCT) ERG....
Abstract The effect of water absorption on the stress transferability across E‐glass fiber/nylon 6 interface has been studied using embedded single fiber composite technique. behavior silane coated and untreated composites after periods immersion were compared. coating provided both higher interfacial shear protection from permanent damage in interphase region. It was found that nylon matrix reduced through plasticization matrix, weakening interface, development tensile swelling stresses at...
The tetrabutylammonium (TBA(+)) salts of square-planar monoanionic gold complexes the unsymmetrically substituted Ar,H-edt(2-) 1,2-dithiolene ligands (Ar,H-edt(2-)=arylethylene-1,2-dithiolato; Ar=phenyl (1(-)), 2-naphthyl (2(-)), and 1-pyrenyl (3(-))) were synthesized characterized by spectroscopic electrochemical methods corresponding neutral species (1, 2, 3, respectively) obtained in CH(2)Cl(2) solution at room temperature diiodine oxidation. single-crystal X-ray diffraction structural...
To assess retinal function in young patients with X-linked juvenile retinoschisis (XLRS), a disorder that is known to alter ERG postreceptor components and also possibly photoreceptor components.ERG responses full-field stimuli were recorded under scotopic photopic conditions 12 XLRS aged 1 15 (median 8) years. A- b-wave amplitudes implicit times examined over range of stimulus intensities. Rod cone (SROD, RROD, SCONE, RCONE) rod-driven (log σ, VMAX) response parameters calculated from the...
Metal bis(1,2-dithiolene) complexes belonging to the class [Ni(Ar-edt)2]x− [Ar-edt2– = arylethylene-1,2-dithiolate; Ar phenyl, (1x–), 2-naphthyl (2x–); x 0 and 1] were fully characterized by NMR, UV–visible–near-infrared (UV–vis–NIR), diffuse reflectance, FT-IR spectroscopy, as well cyclic voltammetry single-crystal X-ray diffraction analysis. These have emerged new photoconducting materials that allowed for development of a prototype photodetectors with response in vis–NIR region. The...
Purpose Low back pain related to intervertebral disc (IVD) degeneration represents a socio-economic problem which affects quality of life. In order solve this the current gold standard techniques such as spinal arthroplasty and arthrodesis (or fusion) are considered. As for arthroplasty, over past 40 yrs, IVD prostheses have been designed maintain correct spacing allow motion, while providing stability. However, there many difficulties in incorporating important features viscoelastic shock...
Small polymeric ducts incorporating a ribbon-shaped mat of densely packed magnetic nanofibers have been manufactured via electrospinning by using cylindrical manifold, alternately under rotation or static.The is located on the side tube and aligned to longitudinal axis assistance field.The designed methodology ensures that particles are completely wrapped into protective polymer shell.Experimental results demonstrate innovative confinement nanofibers, forming ribbon side, confers high...
Background. Actinic keratosis (AK) is a common premalignant skin condition. Its diagnosis based on clinical and sometimes dermoscopic examination, but, in some situations, biopsy may be necessary. Dynamic optical coherence tomography (D-OCT) can often bypass this need, by noninvasive evaluation of morphology. Early effective treatment AKs important to prevent the progression invasive squamous cell carcinoma (iSCC). Tirbanibulin 1% ointment, new topical field therapy for AKs, has recently...
Abstract In this study, we present a systematic analysis of the relation between structural properties and magnetic anisotropies as-grown heat-treated polycrystalline Fe <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" overflow="scroll"> <mml:mrow> <mml:msub> <mml:mi/> <mml:mn>1</mml:mn> <mml:mo>−</mml:mo> <mml:mi>x</mml:mi> </mml:mrow> </mml:msub> </mml:math> Ga x (0.11 <mml:mo><</mml:mo> 0.19) thin films deposited on glass Si(100) substrates. The results show that...