A5039958530- Nanocluster Synthesis and Applications
- Diamond and Carbon-based Materials Research
- Luminescence and Fluorescent Materials
- Carbon Nanotubes in Composites
- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Gold and Silver Nanoparticles Synthesis and Applications
- Crystallography and molecular interactions
- Crystallization and Solubility Studies
- Carbon and Quantum Dots Applications
- X-ray Diffraction in Crystallography
- Advanced Nanomaterials in Catalysis
- Graphene research and applications
- Mycobacterium research and diagnosis
- Graphene and Nanomaterials Applications
- DNA and Nucleic Acid Chemistry
- Nanomaterials for catalytic reactions
- Metal-Organic Frameworks: Synthesis and Applications
- Analytical Chemistry and Sensors
- Boron Compounds in Chemistry
- Copper-based nanomaterials and applications
- Polymer Surface Interaction Studies
- Crystal structures of chemical compounds
- Protein Interaction Studies and Fluorescence Analysis
- Supramolecular Self-Assembly in Materials
UGC-DAE Consortium for Scientific Research, Kolkata Centre
2022-2024
UGC DAE Consortium for Scientific Research
2021-2024
Jadavpur University
2024
Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry
2016-2021
Czech Academy of Sciences
2020-2021
Universität Ulm
2012-2017
Indian Institute of Technology Madras
2009
Nanometer-sized diamonds containing nitrogen-vacancy defect centers (NV) are promising nanosensors in biological environments due to their biocompatibility, bright fluorescence, and high magnetic sensitivity at ambient conditions. Here we report on the detection of ferritin molecules using noise induced by inner paramagnetic iron as a contrast mechanism. We observe significant reduction both coherence relaxation time presence surface nanodiamonds. Our theoretical model is excellent agreement...
Photoluminescent nanosized allotropes of carbon have attracted considerable interest because their diverse optical properties depending on crystal structure, size, and morphology, chemical functionalization. Here, we present the first critical review covering photoluminescence (PL) properties, control, origin in various composites. Different mechanisms by which nanostructures exhibit PL are discussed, involving excitonic nanotubes, thermally activated delayed fluorescence spherical...
Triphenylphosphonium cations strongly enhance the PL quantum yield of near infrared photoluminescent gold nanoclusters by metal-to-ligand charge transfer.
A versatile biopolymer platform for advancing nanodiamonds (NDs) as unique magnetooptic materials biomedical applications is presented here. Precision coatings are designed by chemical reprogramming the functionalities of serum albumin via a straightforward synthesis protocol. Such biopolymers offer high biocompatibility and precise modification with various functional entities due to large number available reactive amino acid residues. Premodification these provides convenient approach...
This is the first experimental evidence that both self-assembly and surface activity are common features of all water-soluble boron cluster compounds. The solution behavior anionic polyhedral boranes (sodium decaborate, sodium dodecaborate, mercaptododecaborate), carboranes (potassium 1-carba-dodecaborate), metallacarboranes {sodium [cobalt bis(1,2-dicarbollide)]} was extensively studied, it evident clusters form multimolecular aggregates in water. However, mechanism aggregation dependent on...
As a step toward deterministic and scalable assembly of ordered spin arrays we here demonstrate bottom-up approach to position fluorescent nanodiamonds (NDs) with nanometer precision on DNA origami structures. We have realized reliable broadly applicable surface modification strategy that results in DNA-functionalized perfectly dispersed NDs were then self-assembled predefined geometries. With optical studies show the fluorescence properties nitrogen-vacancy color centers are preserved...
I-Motif (iM) DNA structures represent among the most significant noncanonical nucleic acid configurations. iM-forming sequences are found in an array of vital genomic locations and particularly frequent promoter islands various oncogenes. Thus, iM is a crucial candidate for anticancer medicines; therefore, binding interactions between small molecular ligands, such as flavonoids, critically important. Extensive sets spectroscopic strategies thermodynamic analysis were utilized present...
Abstract Reaction of [Cp*Fe(CO) 2 I] (Cp* = η 5 ‐C Me ) with an excess amount BH 3 · thf in toluene at 75 °C or LiBH 4 –78 leads to the isolation hydrogen‐rich ferraborane arachno ‐[Cp*Fe(CO)B H 8 ] good yield. In a similar fashion, reaction [Cp*M(CO) Cl] (M Mo and W) 80 yielded metallaboranes [(Cp*M) B 9 Mo, W). Isolated yields closo ‐[(Cp*M) ], W), both from thf, are good. All compounds were characterized solution by IR, 1 H, 11 B, 13 C NMR spectroscopy mass spectrometry structural types...
Research on the interactions of naturally existing flavonoids with various noncanonical DNA such as i-motif (IM) structures is helpful in comprehending molecular basis binding mode well providing future direction for application and invention novel effective therapeutic drugs. IM have been identified prospective anticancer targets, are smaller molecules a variety health-promoting attributes, including activities. The extensive investigation comprising series techniques reveals contrasting...
Harmaline and harmine are two structurally similar β-carboline alkaloids with several therapeutic activities, such as anti-inflammatory, antioxidant, neuroprotective, nephroprotective, antidiabetic, antitumor activities. It has been previously reported that the interaction between harmaline hemoglobin (Hb) is weak in buffer media compared to harmine. Crowding agents induce a molecular crowding environment ex vivo condition, which almost intracellular environment. In this present study, we...
Abstract In this work, a core‐substituted NMI‐conjugated dipeptide (4MNLV) was extensively studied in mixed solvent systems to explore the polarity effect on self‐assembly pattern and their photophysical property. 4MNLV adopted J‐ or H ‐ type aggregation depending upon index of system chosen. The process achieved through anti‐solvent effect. UV‐vis study suggested that if stock solution diluted with relatively more polar (compared solvent), then acquired by showing red‐shift absorption...
A convenient approach for the synthesis of narrowly dispersed polypeptide copolymers defined compositions is presented. The controlled denaturation proteins serum albumin and lysozyme followed by an in situ stabilization with polyethylene(oxide) chains yields side chain precisely backbone lengths as well presence secondary structure elements. Supramolecular architectures are formed solution because hydrophobic hydrophilic amino acids along main chain. Polypeptide reported herein reveal...
Designing novel functional compounds is a key step in coordination and organic materials chemistry. Herein, 9-phenanthrenylvinyl-4′-pyridine (9-PheVP), as new ligand, has been synthesized structurally characterized for the first time, along with its N-methylated analogue (9-MPheVP). Both have explored their photophysical redox properties applicability bioimaging. The effect of quaternization on crystal structure, absorption, emission, investigated. Bathochromic hypochromic shifts were...
We report a bioinspired multifunctional albumin derived polypeptide coating comprising grafted poly(ethylene oxide) chains, multiple copies of the HIV TAT peptide enabling cellular uptake as well mitochondria targeting triphenyl-phosphonium (TPP) groups. Exploring these copolymers for passivating gold nanoparticles (Au NPs) yielded (i) NIR-emitting markers in confocal microscopy and (ii) photo-thermal active probes optical coherence microscopy. demonstrate great potential such...
Extraction and concentration of pure nucleic acid from complex biofluids are the prerequisite for amplification test (NAAT) applications in pathogen detection, biowarfare prevention, genetic diseases. However, conventional spin-column mediated extraction is constricted by requirement costly power-intensive centralized lab infrastructure, making it unsuitable limited-resource settings. Significant progress lab-on-a-chip devices or cartridges (e.g., Cepheid GeneXpert®) that integrate has been...
Harmine and harmaline are two structurally similar heterocyclic β-carboline plant alkaloids with various therapeutic properties, having a slight structural difference in the C3=C4 double bond. In present study, we have reported nature of interaction between hemoglobin (Hb) harmine by employing several multispectroscopic, calorimetric, molecular docking approaches. Fluorescence spectroscopic studies shown stronger Hb compared to that almost harmaline. Steady-state anisotropy experiments...