- Bone health and osteoporosis research
- Pituitary Gland Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Hormonal Regulation and Hypertension
- Adrenal Hormones and Disorders
- Thyroid Disorders and Treatments
- Nutrition and Health in Aging
- Growth Hormone and Insulin-like Growth Factors
- Bone Metabolism and Diseases
- Diabetes Treatment and Management
- Glioma Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Bone health and treatments
- Thyroid and Parathyroid Surgery
- Cancer Immunotherapy and Biomarkers
- Hip and Femur Fractures
- Cancer Diagnosis and Treatment
- Vitamin D Research Studies
- Parathyroid Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- BRCA gene mutations in cancer
- Neuroendocrine Tumor Research Advances
- Cancer, Hypoxia, and Metabolism
- AI in cancer detection
Chonnam National University
2018-2025
Nanjing University of Chinese Medicine
2023-2025
Jiangsu Province Hospital
2023-2025
Chonnam National University Hwasun Hospital
2019-2024
Hospital Doctor José Molina Orosa
2024
Seoul National University
2013-2022
Chonnam National University Hospital
2020-2022
Catholic University of Korea
2022
Seoul National University Hospital
2015-2020
National University College
2020
The prediction of fracture risk in osteoporotic patients has been a topic interest for decades, and models have developed the accurate fracture, including assessment tool (FRAX). As machine-learning methodologies recently emerged as potential model medical tools, we aimed to develop novel using methods prospective community-based cohort. In this study, 2227 participants (1257 females) with baseline bone mineral density (BMD) trabecular score were enrolled from Ansung primary endpoint was...
Young Joo Park, Eun Kyung Lee, Shin Song, Bon Seok Koo, Hyungju Kwon, Keunyoung Kim, Mijin Bo Hyun Won Gu Bae Woong Jung-Han Hee Na, Je Moon, Jung-Eun Sohyun Jun-Ook Ji-In Bang, Kyorim Back, Youngduk Seo, Dong Yeob Shin, Su-Jin Hwa Ahn, So Oh, Seung Hoon Woo, Ho-Ryun Won, Chang Hwan Ryu, Jee Yoon, Ka Yi, Min Kyoung Sang-Woo Sihoon Ah Joon-Hyop Ji Ye Jieun Cho Rok Dong-Jun Lim, Jae-Yol Yun Jeon, Kyong Yeun Jung, Ari Chong, Jae Chung, Chan Kwon Kwanhoon Jo, Yoon Cho, A Ram Hong, Chae Moon...
Recently, the European Society of Endocrinology (ESE), in collaboration with Network for Study Adrenal Tumors (ENSAT), asserted that adrenal incidentalomas (AIs) <4 cm and ≤10 Hounsfield units (HU) do not require further follow-up imaging. To validate clinical application strategies suggested by 2016 ESE-ENSAT guidelines, we explored characteristics natural course AIs a single center over 13 years.This retrospective cohort study included total 1149 patients diagnosed between 2000 2013...
Over the past several decades, there has been a rapid worldwide increase in prevalence of papillary thyroid cancer (PTC) as well number changes clinicopathological characteristics this disease. BRAF(V600E), which is mutation proto-oncogene BRAF, become most frequent genetic associated with PTC, particularly Korea. Thus, present study investigated whether BRAF(V600E) increased over two decades Korean population and various PTC-related have changed.The included 2,624 patients who underwent...
Objective Many malignant tumors initially appear benign but subsequently exhibit extensive metastases. Early identification of pheochromocytomas and paragangliomas (PPGLs) before metastasis is important for improved prognosis. However, there are no robust prognostic indices recurrence malignancy. The aim this study was to identify the clinical histopathological factors that predict PPGLs. Design Retrospective follow-up study. Methods In study, we included 223 patients with pathologically...
Objectives Recently, somatic mutations in KCNJ5, ATP1A1, ATP2B3, and CACNA1D genes were found to be associated with the pathogenesis of aldosterone-producing adenoma (APA). This study aimed investigate prevalence examine correlations between these clinical biochemical characteristics Korean patients APA. Methods We performed targeted gene sequencing 66 APA detect genes. Results Somatic KCNJ5 47 (71.2%) (31 cases p.G151R 16 p.L168R); two mutually exclusive. not observed. more prevalent female...
Thyroid immune-related adverse events (IRAEs) have been reported in patients treated with programmed cell death protein-1 (PD-1) and protein-ligand 1 (PD-L1) inhibitors. We investigated the incidence clinical course of PD-1/PD-L1 inhibitor-induced thyroid IRAEs, identified predictable risk factors particular, overt hypothyroidism (OH).We retrospectively reviewed medical records 325 cancer receiving inhibitor a tertiary referral center.A total 50.5% (164/325) experienced at least one abnormal...
Background/Aims Body mass index (BMI) is positively associated with bone mineral density and type 2 diabetes. We investigated an optimal BMI range for osteoporosis Methods This cross-sectional study used data from the Korea National Health Nutrition Examination Survey (KNHANES), 2008 to 2011. included 3,774 men aged > 50 years 4,982 postmenopausal women. Logistic regression models were applied elucidate each category's diabetes risks. Results The prevalence of was 9.0% 40.8% in 19.7% women...
Background Although infrequent, distant metastasis from differentiated thyroid cancer is the main cause of mortality in patients and mostly involves lung, bone, brain. Distant metastases to other sites are rare, thus, clinical course unusual has not been adequately researched. In present study, clinico-pathological findings treatment outcomes Korea were evaluated. Patients methods We retrospectively reviewed medical records with four Korean tertiary hospitals (Chonnam National University...
Unilateral adrenalectomy is the first-line treatment for aldosterone-producing adenomas (APA). Hyperkalemia after because of contralateral zona glomerulosa insufficiency has been reported. We investigated clinical risk factors to predict postoperative hyperkalemia in patients with APA undergoing adrenalectomy.This study was conducted by retrospectively reviewing medical records from 2000 2012 at Seoul National University Hospital and two other tertiary centers. Data 124 who underwent were...
This study aimed to evaluate the efficacy and safety of sodium-glucose cotransporter-2 (SGLT2) inhibitors in Korean patients who had inadequately controlled type 2 diabetes mellitus (T2DM) real-world clinical practice.We included 410 started SGLT2 (empagliflozin or dapagliflozin) as add-on therapy switch between February 2015 June 2017. The primary endpoint was a change glycosylated hemoglobin (HbA1c) from baseline week 12. secondary endpoints were achieving HbA1c <7.0% changes fasting...