A5028526982- Growth Hormone and Insulin-like Growth Factors
- Pancreatic function and diabetes
- Diabetes Management and Research
- Sexual Differentiation and Disorders
- Vitamin D Research Studies
- Diabetes and associated disorders
- Parathyroid Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Hypothalamic control of reproductive hormones
- Thyroid and Parathyroid Surgery
- COVID-19 Clinical Research Studies
- Childhood Cancer Survivors' Quality of Life
- Lipid metabolism and disorders
- 3D Printing in Biomedical Research
- Neonatal Respiratory Health Research
- Male Breast Health Studies
- Genomic variations and chromosomal abnormalities
- Renal and related cancers
- Bone health and treatments
- Lysosomal Storage Disorders Research
- Birth, Development, and Health
- Breastfeeding Practices and Influences
- Cancer Genomics and Diagnostics
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Osteomyelitis and Bone Disorders Research
Kyungpook National University Hospital
2018-2025
Kyungpook National University
2013-2021
Huntsman Cancer Institute
2004
University of Kansas Medical Center
2004
Young Joo Park, Eun Kyung Lee, Shin Song, Bon Seok Koo, Hyungju Kwon, Keunyoung Kim, Mijin Bo Hyun Won Gu Bae Woong Jung-Han Hee Na, Je Moon, Jung-Eun Sohyun Jun-Ook Ji-In Bang, Kyorim Back, Youngduk Seo, Dong Yeob Shin, Su-Jin Hwa Ahn, So Oh, Seung Hoon Woo, Ho-Ryun Won, Chang Hwan Ryu, Jee Yoon, Ka Yi, Min Kyoung Sang-Woo Sihoon Ah Joon-Hyop Ji Ye Jieun Cho Rok Dong-Jun Lim, Jae-Yol Yun Jeon, Kyong Yeun Jung, Ari Chong, Jae Chung, Chan Kwon Kwanhoon Jo, Yoon Cho, A Ram Hong, Chae Moon...
Purpose We investigated the vitamin D status of preterm infants to determine incidence deficiency. Methods A total 278 delivered at Kyungpook National University Hospital between January 2013 and May 2015 were enrolled. The serum concentrations calcium, phosphorous, alkaline phosphatase, 25-hydroxyvitamin (25-OHD) measured birth. collected maternal neonatal data such as gestational diabetes, premature rupture membranes, preeclampsia, birth date, age, weight. Results Mean age was 33+5±2+2...
Discontinuing growth hormone (GH) treatment during the transition to adulthood has been associated with adverse health outcomes in patients childhood-onset deficiency (CO-GHD). This study investigated metabolic changes interrupting GH adolescents CO-GHD period.This included 187 who were confirmed have adult GHD and treated at six academic centers Korea. Data on clinical parameters, including anthropometric measurements, profiles, bone mineral density (BMD) end of childhood treatment,...
The coronavirus disease 2019 (COVID-19) outbreak in the Daegu-Gyeongbuk area 2020 has caused difficulties daily life and hospital care of children with type 1 diabetes mellitus (T1DM). We detected an increase blood sugar levels these number patients hospitalized more severe diabetic ketoacidosis (DKA) compared to those before COVID-19.This single-center study was conducted at Kyungpook National University Children's Hospital. following patient groups were included; 45 returning diagnosed...
Kabuki syndrome is characterized by distinctive facial features and varying degrees of growth retardation. It leads to malformations in skeletal, urogenital cardiac structures; moreover, endocrine conditions such as premature thelarche, precocious puberty, hormone deficiency, diabetes insipidus, thyroid dysfunction obesity have been reported. caused a heterozygous mutation the KMT2D or KDM6A genes. An 11-year-old girl with typical visited our hospital due her short stature. She was found de...
Jung-Eun Moon, So Won Oh, Ho-Cheol Kang, Bon Seok Koo, Keunyoung Kim, Sun Wook Woong Jung-Han Dong Gyu Na, Sohyun Park, Young Joo Jun-Ook Ji-In Bang, Kyorim Back, Youngduk Seo, Shin Song, Seung Hoon Woo, Ho-Ryun Won, Chang Hwan Ryu, Sang-Woo Lee, Eun Kyung Joon-Hyop Jieun Cho Rok Dong-Jun Lim, Jae-Yol Ari Chong, Yun Jae Chung, Chae Moon Hong, Hyungju Kwon, Ah Korean Thyroid Association Guideline Committee on the Managements of Nodule and Cancer. Int J Thyroidol 2024;17:193-207....
Children with comorbidities have a higher risk of severe, coronavirus disease 2019 (COVID-19). This study investigated the clinical features and outcomes COVID-19 in children adolescents diabetes between January March 2022.
Various endocrine dysfunctions occur during chemotherapy, including hypoglycemia. However, reports of hypoglycemia associated with 6-mercaptopurine (6-MP) are rare. Herein, we report an 8-year-old boy severe symptomatic likely due to 6-MP chemotherapy. He had been diagnosed acute lymphoblastic leukemia 3 years previously and was in the maintenance chemotherapy period. Treatment included oral dexamethasone, methotrexate, 6-MP, which only administered daily. Hypoglycemic symptoms appeared...
Purpose Cytochrome P450 oxidoreductase (POR) deficiency is a rare autosomal recessive disorder caused by mutations in the POR gene encoding an electron donor for all microsomal enzymes. It characterized adrenal insufficiency, ambiguous genitalia, maternal virilization during pregnancy, and skeletal dysplasia. In this study, we investigated clinical, hormonal, molecular characteristics of patients with Korea. Methods This study included four confirmed biochemical analysis POR. Clinical...
Autosomal-dominant hypocalcemia with hypercalciuria (ADHH) is a genetic disease characterized by hypoparathyroidism hypercalciuria. Most patients ADHH have calcium-sensing receptor (CaSR) gene mutations. The CaSR controls parathyroid secretions, and mutations in this can be detected via changes serum calcium level. activating mutation of the results familial or sporadic ADHH. are reportedly de novo missense This first case report novel variant neonate congenital hypomagnesemia We also...
We aimed to investigate the changes in vitamin D levels and factors associated with deficiency (VDD) during first year of life Korean preterm infants. enrolled 333 infants who were born at Kyungpook National University Children’s Hospital between March 2013 December 2019. 25-hydroxyvitamin (25-OHD) medical records collected birth, 6 months, 12 months age. The mean gestational age was 33.4 ± 2.3 weeks 25-OHD birth 18.2 13.5 ng/mL. incidence VDD 82.8%, 30.6%, 27.0% respectively. severe (25-OHD...
Growth hormone (GH) treatment is recommended to improve growth and psychosocial problems in short stature children born small for gestational age (SGA). Although GH therapy these patients has been extensively studied, the impact of according delays bone (BA) not known well.To investigate effects SGA with BA delay.We retrospectively analyzed changes height SD score (SDS) BA/chronological (CA) after 6 12 months grouped delay. We studied 27 pediatric endocrinology clinic Kyungpook National...
Abstract Background Gynecomastia develops due to the reversed estradiol-to-Testosterone ratio in adolescence, and symptoms typically improve within 2 years. The causes vary widely, including estrogen excess tumors, surgical treatment is usually given late adolescence because postoperative may recur adolescents. This study reports a case of pediatric patient with severe gynecomastia excessive estradiol secretion who showed positive outcome after receiving combined aromatase inhibitor...
Alport syndrome (AS) is a rare genetic disorder that causes progressive nephritis and more common among males. Studies have reported an association between thyroid antibodies hypothyroidism in patients with AS, but the relevance of this relationship under debate. Prolonged untreated induces short stature, abnormal pubertal development, various other symptoms. However, children long-standing rarely present signs precocious puberty, or Van Wyk-Grumbach (VWGS). We report case boy, 8 years 4...
To analyse the perspectives of healthcare professionals (HCPs) regarding acceptance digital health solutions for growth hormone (GH) deficiency care. This study identified factors impacting HCPs' intent to use and recommend supporting recombinant-human (r-hGH) therapy in Italy Korea with a case connected drug delivery system (Aluetta
Abstract Background Toy slime is popular in Korea, and parallel, pre-pubertal girls visit hospitals for early pubertal signs. Thus far, numerous studies have investigated the association of endocrine-disrupting chemicals (EDCs) with precocious puberty (PP). However, there a lack on clinical manifestations sex hormones. We aimed to investigate development Korean or without history toy exposure determine changes bone age, Tanner stage, Methods In this study, 140 underwent stimulation tests at...
Rare endocrine diseases are complex conditions that require lifelong specialized care due to their chronic nature and associated long-term complications. In Korea, a lack of nationwide data on clinical practice outcomes has limited progress in patient care. Therefore, the Multicenter Networks for Ideal Outcomes Pediatric Endocrine Metabolic Disease (OUTSPREAD) study was initiated. This involves 30 centers across Korea. The aims improve prognosis Korean patients with rare by collecting...
Pheochromocytoma (PCC) occurs in 4% of pediatric neurofibromatosis type 1 (NF1) patients and is characterized by epinephrine norepinephrine secretion. Herein, we report the first case dopamine-secreting PCC a 13-year-old patient with NF1. A left adrenal mass was incidentally found on abdominal computed tomography (CT ) during hypertension workup. Fractionated 24-hour urine metanephrine excretion normal, but dopamine level elevated. Focal 123I-metaiodobenzylguanidine uptake observed...
Purpose Autosomal dominant hypocalcemia with hypercalciuria is a genetic disease characterized by hypoparathyroidism hypercalciuria. We discovered novel variant (p.Tyr825Phe[Y825F]) of the <i>CASR</i> gene in neonate congenital and conducted cell function study to determine whether CASR-Y825F was pathogenic. Methods To perform functional on CaSR-Y825F, we constructed expression vectors expressing wild-type (WT) CASR CASR-Y825F. After transfection each vector into HEK293 cells, examined...
We aimed to determine the incidence of acute kidney injury (AKI) and longitudinal changes in SCr levels urinary biomarkers associated with AKI aminoglycoside (AG) medication during first week life late preterm infants. Urine were measured thirty infants on days one, two, five, seven postnatal. included neutrophil gelatinase-associated lipocalin (NGAL), monocyte chemotactic protein-1 (MCP-1), epidermal growth factor (EGF), Tamm-Horsfall glycoprotein (THP), liver fatty-acid-binding protein...