Xin Yu

ORCID: 0000-0002-2534-5190
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About
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Research Areas
  • Metabolism, Diabetes, and Cancer
  • Cancer, Hypoxia, and Metabolism
  • Growth Hormone and Insulin-like Growth Factors
  • Adipose Tissue and Metabolism
  • Hepatitis B Virus Studies
  • Biomedical Ethics and Regulation
  • Diet and metabolism studies
  • Surface Roughness and Optical Measurements
  • Advanced MRI Techniques and Applications
  • Ocular Oncology and Treatments
  • Nutrition and Health in Aging
  • Brain Tumor Detection and Classification
  • Functional Brain Connectivity Studies
  • Cancer, Lipids, and Metabolism
  • Pain Mechanisms and Treatments
  • Phytoestrogen effects and research
  • RNA modifications and cancer
  • HIV-related health complications and treatments
  • Optical Systems and Laser Technology
  • interferon and immune responses
  • Bladder and Urothelial Cancer Treatments
  • Ferroptosis and cancer prognosis
  • Pain Management and Treatment
  • Hepatitis C virus research
  • Muscle Physiology and Disorders

Wuhan University
2023-2024

Renmin Hospital of Wuhan University
2023-2024

Zhejiang University
2016-2024

Shandong Academy of Sciences
2023

Qilu University of Technology
2023

Qilu Hospital of Shandong University
2023

Shandong University
2023

Shanghai Clinical Research Center
2023

Eighth Affiliated Hospital of Sun Yat-sen University
2022

Sun Yat-sen University
2022

Diabetic sarcopenia (DS) is characterized by muscle atrophy, slower nerve conduction, reduced maximum tension generated skeletal contraction, and contraction rate. Hence, DS can cause limb movement degeneration, slow movement, balance, metabolic rate, falls, fractures, etc. Moreover, the relevant early biological metabolites their pathophysiological mechanism have yet to be characterized.The current cross-sectional study employed serum metabolomics analysis screen potential noninvasive...

10.3389/fendo.2023.1119782 article EN cc-by Frontiers in Endocrinology 2023-03-22

Chronic hepatitis B (CHB) remains a significant global health problem, leading to recurrent inflammation and liver-damaging diseases such as fibrosis, cirrhosis, hepatocellular carcinoma (HCC). Currently, although diagnostic markers for CHB are well established, the indicators predicting liver injury caused by virus (HBV) infection still need be further explored. Thus, identification of credible infectious is urgently needed facilitate timely clinical intervention avoid progression disease...

10.3389/fmicb.2022.1052917 article EN cc-by Frontiers in Microbiology 2022-11-24

As the most common aggressive intraocular cancer in adults, uveal melanoma (UVM) threatens survival and vision of many people. Glycolysis is a novel hallmark cancer, but role glycolysis-related genes UVM prognosis remains unknown. The purpose study was to establish gene signature (GRGS) predict prognosis.Raw data were obtained from TCGA-UVM GSE22138 datasets. GRGS established by univariate, LASSO, multivariate Cox regression analyses. Kaplan-Meier time-dependent receiver operating...

10.1159/000529818 article EN cc-by-nc Ophthalmic Research 2023-01-01

Summary As meat quality is basically dependent on muscle fibre characteristics, it important to know how fibres are regulated and transformed. This study aimed investigate the effect of maternal dietary supplementation types using 3% saturated fatty acid (palmitic acid, PA ) or unsaturated (linoleic LA from 80 days gestation weaning offspring (25 post‐natal). The results indicated that higher mRNA levels My HCI type genes were found in soleus muscles piglets suckled ‐supplemented sows than...

10.1111/jpn.12626 article EN Journal of Animal Physiology and Animal Nutrition 2016-10-20

Pain is an experience of unpleasant sensations and emotions associated with actual or potential tissue damage. In the global context, billions people are affected by pain disorders. There particular challenges in measurement assessment pain, commonly used measuring tools include traditional subjective scoring methods biomarker-based measures. The main for analysis electroencephalography (EEG), electrocardiography functional magnetic resonance. EEG-based quantitative measurements immense...

10.1142/s0129065723500673 article EN International Journal of Neural Systems 2023-10-20

CDK6 is linked to tumor progression and metastasis, although its molecular mechanism prognostic value are unclear in bladder cancer.

10.7150/ijms.101043 article EN cc-by-nc International Journal of Medical Sciences 2024-01-01

The Golgi apparatus (GA), an organelle that processes, sorts, and transports proteins synthesized by the endoplasmic reticulum, is also involved in many cellular processes associated with cancer, such as angiogenesis, innate immune response, tumor invasion migration. We aimed to construct a breast cancer (BC) prognosis prediction model based on GA-related genetic information evaluate of patients BC more accurately than existing models stratify for clinical therapy. In this study, Cancer...

10.1097/md.0000000000039177 article EN cc-by-nc Medicine 2024-08-16

IGFBP6, a member of the IGF binding protein (IGFBP) family, is specific inhibitor insulin-like growth factor II (IGF-II) and can inhibit malignant tumors overexpressing IGF-II. Type 2 diabetes (T2D) basic disorder glucose metabolism that be regulated by IGF-related pathways. We performed bioinformatics analysis TCGA database to explore possible mechanism IGFBP6 in breast cancer (BC) prognosis collected clinical samples from BC patients with without T2D compare verify prognostic effect...

10.1177/15330338241271998 article EN cc-by-nc Technology in Cancer Research & Treatment 2024-01-01

Motivation: We address the need for standardization and collaboration in rat sensory-evoked fMRI by providing evidence-based recommendations open-access datasets, fostering community growth. Goal(s): aim to assess inter- intra-datasets variability, focusing on image acquisition experimental protocols, optimize analysis comparing hemodynamic response functions denoising methods. Approach: collected 17 datasets from 10 centers, applied standardized preprocessing, analyzed responses at...

10.58530/2024/3324 article EN Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition 2024-11-26

To analyze the fatty acid content of Jiangnan dishes in Hangzhou.

10.19813/j.cnki.weishengyanjiu.2024.06.012 article EN PubMed 2024-11-01

<div>Abstract<p>Chemotherapy and radiation are more effective in wild-type (WT) p53 tumors due to activation. This is one rationale for developing drugs that reactivate mutant synergize with chemotherapy radiation. Zinc metallochaperones (ZMC) a new class of reactivators restore WT structure function zinc-deficient mutants. We hypothesized the thiosemicarbazone, ZMC1, would Surprisingly, this was not found. explored mechanism found reactive oxygen species (ROS) activity ZMC1...

10.1158/1535-7163.c.6538219 preprint EN 2023-04-03

Abstract IGFBP6, as a member of the IGF binding proteins (IGFBPs) family, is specific inhibitor insulin-like growth factor II (IGF-II) and can inhibit malignant tumors overexpressing IGF-II. Type 2 diabetes (T2D) basic disorder glucose metabolism which regulated by IGF-related pathways. IGFBP6 expression downregulated in serum tumor tissue colorectal cancer patients with T2D. We analyzed TCGA database bioinformatics to explore possible mechanism breast (BC) prognosis, collected clinical...

10.21203/rs.3.rs-3274239/v1 preprint EN cc-by Research Square (Research Square) 2023-09-14

It has been established that the administration of phenobarbital to rats produces an accumulation triglyceride in liver. In present study, it demonstrated increases hepatic lipid peroxidation as reflected by observed diene conjugation absorption microsomal lipids well increase malonic dialdehyde formation. Both fatty infiltration and lipoperoxidation were found be inhibited antioxidant. N, N′-diphenyl-p-phenylenediamine. These data suggest peroxidative process may play a role phenobarbital-induced

10.1016/0006-355x(95)92287-k article EN Biorheology 1995-03-01

The relationship between the performance of a partial correction adaptive telescope using laser guide stars and star brightness is discussed. energy requirements for Rayleigh as well sodium are presented in cases where diameter d subaperture larger than atmospheric coherence length r<SUB>0</SUB> residual rms phase error across 0.63.

10.1117/12.255112 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 1996-10-12
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