A5067188943- Digital Mental Health Interventions
- Health Policy Implementation Science
- Mental Health Treatment and Access
- Health disparities and outcomes
- Mental Health and Patient Involvement
- Treatment of Major Depression
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health Research Topics
- Health, psychology, and well-being
- Impact of Technology on Adolescents
- Smoking Behavior and Cessation
- Tryptophan and brain disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Cardiac Health and Mental Health
- Employment and Welfare Studies
- Global Health Workforce Issues
- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Ethics in Clinical Research
- Memory and Neural Mechanisms
- Adolescent and Pediatric Healthcare
- Financial Literacy, Pension, Retirement Analysis
- Electroconvulsive Therapy Studies
- Global Health Care Issues
- Healthcare Decision-Making and Restraints
University College London
2018-2024
Faculty (United Kingdom)
2023
University College Lahore
2020
Mental Health Research UK
2019
University of Oxford
2015-2016
Wellcome Centre for Integrative Neuroimaging
2016
Warneford Hospital
2015
People with severe mental illnesses such as schizophrenia are three times more likely to smoke than the wider population, contributing widening health inequalities. Smoking remains largest modifiable risk factor for this inequality, but people illness have not historically engaged smoking cessation services. We aimed test effectiveness of a combined behavioural and pharmacological intervention targeted specifically at illness.In (SCIMITAR+) trial, pragmatic, randomised controlled study, we...
Depression and anxiety symptoms are common among university students, but many do not receive treatment. This is often because of lack availability, reluctance to seek help, meeting the diagnostic criteria required access services. Internet-based interventions, including smartphone apps, can overcome these issues. However, a large number apps available, each with little evidence their effectiveness.This study aims evaluate for first time effectiveness self-guided mobile app, Feel Stress...
BackgroundIt is unclear whether young people who attend higher education are at increased risk of common mental disorders, compared with those do not attend. We aimed to investigate attendance was associated symptoms disorders (depression and anxiety) in before, during after attendance.MethodsFor this cohort study, we used two cohorts—the Longitudinal Studies Young People England (LSYPE1: N=4832, 55·8% [2696 4832] students; LSYPE2: n=6128, 50·7% [3104 6128] students), beginning 2004 for...
Abstract Background People with severe mental illness (SMI) are at greater risk of earlier mortality due to physical health problems including cardiovascular disease (CVD). There is limited work exploring whether interventions for people SMI can be embedded and/or adopted within specific healthcare settings. This information necessary optimise the development services and study explores barriers facilitators implementing a nurse-delivered intervention (‘PRIMROSE’) designed reduce CVD in...
Randomised controlled trials (RCT) can struggle to recruit target on time. This is especially the case with hard reach populations such as those severe mental ill health. The SCIMITAR+ trial, a trial of bespoke smoking cessation intervention for people health achieved their recruitment ahead time and target. article reports strategies that helped us achieve this aim aiding others recruiting from similar populations. multi-centre pragmatic two-arm parallel-group RCT, which aimed 400...
Apolipoprotein (APOE) ɛ4 genotype has been identified as a risk factor for late-onset Alzheimer disease (AD). The memory system is mostly involved in AD, and deficits represent its key feature. A growing body of studies focused on the earlier identification cognitive dysfunctions younger older APOE carriers, but investigation middle-aged individuals remains rare. Here we sought to investigate if modulates declarative influences perception middle life span. We tested 60 recruited according...
Abstract Purpose Psychotic like experiences (PLEs) are relatively common during adolescence and associated with a range of negative outcomes. There is evidence that sexual minorities at increased risk mental health problems including depression, anxiety, self-harm suicidality. However, no study has investigated the association between orientation psychotic adolescence. We compared trajectories PLEs in minority heterosexual adolescents from 12 to 24 years age. Methods used data Avon...
Abstract Anxiety involves the anticipation of aversive outcomes and can impair neurocognitive processes, such as ability to recall faces encoded during anxious state. It is important precisely delineate determine replicability these effects using causal state anxiety inductions in general population. This study therefore aimed replicate prior research on distinct impacts threat-of-shock-induced encoding recognition stage emotional face processing, a large asymptomatic sample ( n = 92). We...
Selective serotonin reuptake inhibitors (SSRIs) are used for the treatment of several conditions including anxiety disorders, but basic neurobiology function remains unclear. The amygdala and prefrontal cortex strongly innervated by serotonergic projections have been suggested to play an important role in expression. However, behaviour SSRI-mediated neurobiological changes remain incompletely understood.
Background There is a high prevalence of smoking among people with severe mental ill health (SMI). Helping SMI to quit could improve their and longevity, reduce inequalities. However, those are less likely access engage routine cessation services than the general population. Objectives To compare clinical effectiveness cost-effectiveness bespoke (BSC) intervention usual stop for SMI. Design A pragmatic, two-arm, individually randomised controlled trial. Setting Primary care secondary in...
It is not clear to what extent associations between schizophrenia, cannabis use and cigarette are due a shared genetic etiology. We, therefore, examined whether schizophrenia risk associates with longitudinal patterns of in adolescence mediating pathways for any association inform potential reduction strategies.
Purpose Financial difficulties are associated with poor student mental health, although the 2012 tuition fees increase for British students had little impact on health in first two years at university. This study aims to examine of graduates before and after this determine several graduation. Design/methodology/approach conducted an online cohort 327 who started university increase. Participants completed measures current economic hardship symptoms depression, anxiety, stress, general...
Abstract Background In recent years there has been increasing concern for the wellbeing of higher education students, and institutions are under pressure to act. Loneliness social isolation appear common among particularly postgraduate taught (PGT) linked adverse outcomes such as depression abandoning studies. We have in place a novel curriculum-based peer support intervention (“study groups”) that may help mental health students. Aim This study aimed explore student staff experiences groups...
Abstract Background Social anxiety disorder is a common mental health condition characterized by an intense fear of social situations which can lead to significant impairment in daily life. Cognitive behavioral therapy (CBT) has been recognized as effective treatment; however, access therapists limited and the interacting with delay treatment seeking. Furthermore, not all individuals respond. Tailoring modular treatments individual cognitive profiles may improve efficacy. We developed novel...
Abstract Social anxiety disorder is a debilitating mental health condition characterized by intense fear of social situations that can significantly impair daily life if left untreated. Cognitive behavioral therapy (CBT) an effective treatment, but many patients experience slow progress, possibly due to the heterogeneity cognitive dysfunction contributing maintenance disease not adequately reflected in typical one-size-fits-all CBT approach. In addition, only seek treatment late, because...
Aims and method The SCIMITAR+ trial was commissioned to evaluate the effectiveness of a bespoke smoking cessation intervention for people with severe mental ill health compared usual services. It is difficult define what constitutes care in We aimed this during trial. Twenty-two National Health Service healthcare providers participated survey asking about their area. Results All sites offered support; however, service provider type varied substantially. In some cases services were not...
Abstract Background: People with severe mental illness (SMI) are at greater risk of earlier mortality due to physical health problems including cardiovascular disease (CVD). There is limited work exploring whether interventions for people SMI can be embedded and/or adopted within specific healthcare settings. This information necessary optimise the development services and study explores barriers facilitators implementing a nurse-delivered intervention (‘PRIMROSE’) designed reduce CVD in...
<sec> <title>BACKGROUND</title> Depression and anxiety symptoms are common among university students, but many do not receive treatment. This is often because of lack availability, reluctance to seek help, meeting the diagnostic criteria required access services. Internet-based interventions, including smartphone apps, can overcome these issues. However, a large number apps available, each with little evidence their effectiveness. </sec> <title>OBJECTIVE</title> study aims evaluate for first...