A5101775116- Lung Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Lung Cancer Treatments and Mutations
- Advanced Radiotherapy Techniques
- Lung Cancer Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Nonmelanoma Skin Cancer Studies
- Effects of Radiation Exposure
- Brain Metastases and Treatment
- Breast Lesions and Carcinomas
- Breast Implant and Reconstruction
- Cancer Treatment and Pharmacology
- Intensive Care Unit Cognitive Disorders
- Colorectal Cancer Treatments and Studies
- Respiratory Support and Mechanisms
- Cutaneous Melanoma Detection and Management
- Advances in Oncology and Radiotherapy
- Glioma Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Management of metastatic bone disease
- Prostate Cancer Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Neuroendocrine Tumor Research Advances
- Cancer Genomics and Diagnostics
Saint Louis University
2025
Universitat Pompeu Fabra
2014-2024
Fundación Santa Fe de Bogotá
2021-2024
Universidad de Los Andes
2024
Hospital Universitario La Paz
2000-2024
Hospital del Mar Research Institute
2015-2024
Hospital de Sant Pau
2022-2024
Universidad Autónoma de Madrid
2024
Complejo Hospitalario de Ourense
2024
Parc de Salut
2012-2023
Radiation dose received by the neural stem cells of hippocampus during whole-brain radiotherapy has been associated with neurocognitive decline. The key concern using hippocampal avoidance-prophylactic cranial irradiation (HA-PCI) in patients small-cell lung cancer (SCLC) is incidence brain metastasis within avoidance zone.This phase III trial enrolled 150 SCLC (71.3% limited disease) to standard prophylactic (PCI; 25 Gy 10 fractions) or HA-PCI. primary objective was delayed free recall...
Low-dose dexamethasone demonstrated clinical improvement in patients with coronavirus disease 2019 (COVID-19) needing oxygen therapy; however, evidence on the efficacy of high-dose is limited.We performed a randomised, open-label, controlled trial involving hospitalised confirmed COVID-19 pneumonia therapy. Patients were randomly assigned 1:1 ratio to receive low-dose (6 mg once daily for 10 days) or (20 5 days, followed by an additional days). The primary outcome was worsening within 11...
Abstract Background Flow starvation is a type of patient-ventilator asynchrony that occurs when gas delivery does not fully meet the patients’ ventilatory demand due to an insufficient airflow and/or high inspiratory effort, and it usually identified by visual inspection airway pressure waveform. Clinical diagnosis cumbersome prone underdiagnosis, being opportunity for artificial intelligence. Our objective develop supervised intelligence algorithm identifying deformation during square-flow...
Stage III non-small cell lung cancer (NSCLC) is a very heterogeneous disease that encompasses patients with resected, potentially resectable and unresectable tumours. To improve the prognostic capacity of TNM classification, it has been agreed to divide stage into sub-stages IIIA, IIIB IIIC have different 5-year survival rates (36, 26 13%, respectively). Currently, considered both staging optimal treatment NSCLC requires joint work multidisciplinary team expert physicians within tumour...
While asthma is a known risk factor for Acute Chest Syndrome (ACS) and may increase overall mortality in SCD patients, this study specifically focuses on the rate of inpatient mortality, hospital stay, costs patients who develop ACS. Our was conducted using retrospective cohort from National Inpatient Sample (NIS), spanning 5 years 2016 to 2020. Patients were carefully divided into two cohorts comparison: those admitted with ACS history without asthma. The primary endpoint all-cause we built...
<h3>Background</h3> A large family with autosomal dominant nocturnal frontal lobe epilepsy from the south of Spain was studied. The clinical appearance disease in this family, which included 28 members, whom 11 were affected and 2 obligate carriers, identical to that previously described an Australian a Norwegian mutations exon 5 the<i>CHRNA4</i>gene found. <h3>Methods</h3> Following DNA extraction, genotyped 4 fluorescent markers flanking locus on chromosome 20q13.3, lod score computations...
Background: Ductal lavage has the potential to detect cancer by sampling breast epithelium in asymptomatic high-risk women. To assess utility of ductal as a diagnostic test, we investigated association between cytologic findings and histologic women with known undergoing mastectomy. Methods: was performed operating room before mastectomy on 44 breasts from 32 eight seven prophylactic mastectomy, two occult malignancy. If sample one or more ducts contained enough epithelial cells for...
Testicular germ cell tumors sometimes regress spontaneously and manifest exclusively by metastasis. We report our experience with extragonadal of probable testicular origin to study the frequency this entity, clinical, ultrasound histopathological correlations in a series patients.A retrospective 16-year review 1.2 million inhabitants Spain revealed 17 regressed treated at total 4 institutions. analyzed clinical information, features characteristics lesions metastasis, highlight main...
Autoantibodies raised against tumor-associated antigens have shown high promise as clinical biomarkers for reliable diagnosis, prognosis, and therapy monitoring of cancer. An electrochemical disposable biosensor the specific sensitive determination p53-specific autoantibodies has been developed first time in this work. This involves use magnetic microcarriers (MBs) modified with covalently immobilized HaloTag fusion p53 protein solid supports selective capture autoantibodies. After MBs onto...
Comprehensive assessment of integrated care deployment constitutes a major challenge to ensure quality, sustainability and transferability both healthcare policies services in the transition toward coordinated service delivery scenario. To this end, manuscript articulates four different protocols aiming at assessing large-scale implementation care, which are being developed within umbrella regional project Nextcare (2016-2019), undertaken foster innovation technologically-supported for...
Background and Purpose:The humoral immune response in cancer patients can be used for early detection of the disease.Autoantibodies raised against tumor-associated antigens (TAAs) are promising clinical biomarkers reliable diagnosis, prognosis, therapy monitoring.In this study, an electrochemical disposable multiplexed immunosensing platform able to integrate difficult-and easy-to-express colorectal (CRC) TAAs is reported sensitive determination eight CRC-specific autoantibodies.Methods: The...
Abstract Background Immune check-point blockade (ICB) has shown clinical benefit in mismatch repair-deficient/microsatellite instability high metastatic colorectal cancer (mCRC) but not repair-proficient/microsatellite stable patients. Cancer vaccines with autologous dendritic cells (ADC) could be a complementary therapeutic approach to ICB as this combination the potential achieve synergistic effects. Methods This was Phase I/II multicentric study translational sub-studies, evaluate safety,...