Long Gao

ORCID: 0000-0002-2803-3416
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Nanoplatforms for cancer theranostics
  • Liver Disease and Transplantation
  • Inflammatory Bowel Disease
  • Cancer-related molecular mechanisms research
  • Diabetes Management and Research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Nanoparticle-Based Drug Delivery
  • Acute Lymphoblastic Leukemia research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Advanced Combustion Engine Technologies
  • Fire dynamics and safety research
  • Luminescence Properties of Advanced Materials
  • Combustion and flame dynamics
  • Organ Transplantation Techniques and Outcomes
  • Microwave-Assisted Synthesis and Applications
  • Eosinophilic Esophagitis
  • Hepatitis Viruses Studies and Epidemiology
  • Diabetes and associated disorders
  • Thermochemical Biomass Conversion Processes
  • Diabetes Treatment and Management
  • MicroRNA in disease regulation
  • Bone Tissue Engineering Materials
  • Microscopic Colitis
  • Helicobacter pylori-related gastroenterology studies

First Hospital of Shanxi Medical University
2021-2025

Shanxi Medical University
2021-2025

Harbin Institute of Technology
2022-2023

Lanzhou University
2022-2023

First Hospital of Lanzhou University
2022-2023

Tianjin Medical University
2021

Tianjin Children's Hospital
2021

Tianjin Hospital
2021

National University of Defense Technology
2021

University of Pittsburgh
2021

Clinical characteristics of obesity are heterogenous, but current classification for diagnosis is simply based on BMI or metabolic healthiness. The purpose this study was to use machine learning explore a more precise subgroups towards informing individualized therapy.In multi-center (n=2495), we used unsupervised cluster patients with from Shanghai Tenth People's hospital (n=882, main cohort) three clinical variables (AUCs glucose and insulin during OGTT, uric acid). Verification the...

10.3389/fendo.2021.713592 article EN cc-by Frontiers in Endocrinology 2021-07-14

The incidence of hepatic encephalopathy (HE) was higher within 1 year after transjugular intrahepatic portosystemic shunt (TIPS) in cirrhosis. While some findings showed that the flow correlates with HE, it remains unknown whether stent (SSF) is associated overt-hepatic (OHE). This study, therefore, investigated association between SSF and OHE a TIPS. A digital color ultrasonic diagnostic device used to measure velocity (SFV). then examined using logistic regression restricted cubic spline...

10.1097/meg.0000000000002942 article EN European Journal of Gastroenterology & Hepatology 2025-03-05

BACKGROUND The pathogenesis of hepatic encephalopathy (HE) remains unclear, and the classical theory ammonia toxicity lacks sufficient justification. AIM To investigate potential bile acids as intervention targets for HE. METHODS This study employed 42 wild-type male SD rats weighing 200 ± 20 g. Using a random number table method, two were randomly selected to undergo common duct ligation (BDL). remaining 40 assigned four groups serving controls: vehicle + control diet (VC) group,...

10.4254/wjh.v17.i3.101340 article EN World Journal of Hepatology 2025-03-25

The microcarrier system offers an attractive method for cellular amplification and phenotype enhancement in the field of bone tissue engineering. However, it remains a challenge to fabricate porous microcarriers with osteoinductive activity speedy high-quality osseointegration regeneration serious complication fracture, like nonunion. Here, we present facile first time manufacture osteogenic effects properties based on well controlled long-term Sr2+ release. At first, strontium-substituted...

10.1021/acs.biomac.7b01101 article EN Biomacromolecules 2017-09-29

Abstract The combustible gas produced by coal pyrolysis can be used as a clean fuel to reduce environmental pollution caused combustion. In order improve the efficiency of prepare flammable gases, Ni-Co supported catalysts were prepared equal volume impregnation method using coke different final temperatures carrier in this study. effects and metal loadings on products studied. cracking mechanism was characterized BET, XRD, XPS SEM. results show that: (1) catalytic catalyst is mainly related...

10.1038/s41598-019-44271-7 article EN cc-by Scientific Reports 2019-07-08

Herein, we develop a novel integrated strategy for the preparation of theranostic chitosan microcapsules by encapsulating ion liquids (ILs) and Fe3O4 nanoparticles. The as-prepared chitosan/Fe3O4@IL exhibit not only significant heating efficacy in vitro under microwave (MW) irradiation but also obvious enhancement T2-weighted magnetic resonance (MR) imaging, besides excellent biocompatibility physiological environments. show ideal temperature rise therapeutic efficiency when applied to...

10.1186/s11671-016-1536-0 article EN cc-by Nanoscale Research Letters 2016-07-15

Background: HE is a common and dangerous complication after TIPS. The relationship between IL-6 levels overt (OHE) TIPS rarely reported.We aimed to explore the preoperative serum OHE risk TIPS, evaluate its value in predicting risk. Methods: This prospective cohort study included 125 participants with cirrhosis who received Logistics regression analyses were performed risk, receiver operating characteristic analysis was used compare predictive power of other indexes. Results: Among...

10.1097/hc9.0000000000000128 article EN cc-by-nc-nd Hepatology Communications 2023-04-01

Introduction: The incidence of cholangiocarcinoma (CCA) has increased worldwide in recent years. Given the poor prognosis associated with current management approach CCA, new therapeutic agents are warranted to improve this patient population. Methods: In study, we extracted five cardiac glycosides (CGs) from natural plants: digoxin, lanatoside A, C, B, and gitoxin. Follow-up experiments were performed assess effect these extracts on cells compounds best efficacy selected. Lanatoside C (Lan...

10.3389/fphar.2023.1098915 article EN cc-by Frontiers in Pharmacology 2023-06-15

Flame features and dynamics are important to the explanation prediction of a lean blowout (LBO) phenomenon. In this paper, recognition near-LBO flame oscillation characterization methods were proposed based on spectroscopic images. High-speed planar laser-induced fluorescence measurements OH used capture unique dynamic such as local extinction reignition feature entrained reactant pockets. The Zernike moment demonstrated good performance in stability conditions, though geometric had more...

10.1016/j.cja.2022.05.009 article EN cc-by-nc-nd Chinese Journal of Aeronautics 2022-05-26

Microwave radiation has become an effective catalytic combustion method, especially in the degradation of volatile organic compounds (VOCs) such as toluene using catalysts like MnO2. In this study, a spine waveguide microwave reactor was designed to investigate influence different processing conditions on catalyzed by An experimental system for microwave-assisted established explore relationship between power, catalyst conductivity, and rate. The results showed that efficiency MnO2...

10.3390/pr12061074 article EN Processes 2024-05-24

Residual tumor resulting in recurrence after various anticancer therapies is an unmet challenge current clinical oncology. This study aimed to investigate the hypothesis that radioiodinated hypericin (131I-Hyp) may inhibit residual microwave ablation (MWA) on rat orthotopic liver allograft sarcoma models.Thirty Sprague-Dawley (SD) rats with hepatic tumors were divided into three groups: Group A received laparotomy MWA and sequential intravenous injection (i.v.) of 131I labelled a time...

10.18632/oncotarget.9848 article EN Oncotarget 2016-06-06

Introduction: The CDAI has been the standard outcome measure in CD trials for ˜40 years, but its complexity, high placebo response, and inconsistency with FDA guidance on patient-reported (PRO) measures are disadvantages. This generated interest exploring a PRO based stool frequency (SF) abdominal pain (AP) components of CDAI, known as PRO-2. A potential PRO-2 definition remission (mean daily score AP≤1 AND [also] SF≤1.5) was proposed data from 2 populations, one mild-moderate disease...

10.14309/00000434-201410002-01679 article EN The American Journal of Gastroenterology 2014-10-01

Intrahepatic cholangiocarcinoma (ICC) is a malignant tumor that originates from bile duct’s epithelial cells and usually characterized by insidious symptoms poor prognosis. Cinobufotalin (CB), an active ingredient obtained the Traditional Chinese Medicine ChanSu, purported to exhibit wide range of antitumorigenic activities. However, mechanism which it achieves such pharmacological effects remains elusive. Here, we disclosed action CB inhibits ICC cells. Initial experiments revealed...

10.3389/fonc.2022.982961 article EN cc-by Frontiers in Oncology 2022-09-16
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