A5006474351- Burn Injury Management and Outcomes
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Trauma and Emergency Care Studies
- Pneumothorax, Barotrauma, Emphysema
- Disaster Response and Management
- Abdominal Surgery and Complications
- Thermal Regulation in Medicine
- Acute Kidney Injury Research
- Nosocomial Infections in ICU
- Poisoning and overdose treatments
- Vibrio bacteria research studies
- Antibiotic Resistance in Bacteria
- Renal function and acid-base balance
- Nail Diseases and Treatments
- Pressure Ulcer Prevention and Management
- Pneumonia and Respiratory Infections
- Mechanical Circulatory Support Devices
- Abdominal vascular conditions and treatments
- Polyomavirus and related diseases
- Hemodynamic Monitoring and Therapy
- Injury Epidemiology and Prevention
- Emergency and Acute Care Studies
- Antifungal resistance and susceptibility
- Antibiotic Use and Resistance
Assistance Publique – Hôpitaux de Paris
2016-2025
Hôpital Fernand-Widal
2025
Hôpital Lariboisière
2018-2021
Université Pierre Mendès France
2021
Hôpital Saint-Louis
2016-2018
Abstract Background Burns intensive care units (BICU) have reduced mortality in burns patients, but infections and sepsis remain the leading causes of death. Infections with multidrug-resistant (MDR) bacteria increase risk death whose acquiring such is higher due to various factors, including prolonged hospitalization invasive procedures. Methods A retrospective study was performed a French BICU over eight years, analyze epidemiology factors for bloodstream (BSI). Results In total, 1402...
Abstract Background Dipeptidyl peptidase-3 (DPP3) is a metallopeptidase which cleaves bioactive peptides, notably angiotensin II, and involved in inflammation regulation. DPP3 has been proposed to be myocardial depressant factor circulatory failure acute illnesses, possibly due II cleavage. In this study, we evaluated the association between plasmatic level outcome (mortality hemodynamic failure) severely ill burn patients. Methods biomarker analysis of prospective cohort included adult...
Burn-induced shock can lead to tissue hypoperfusion, including the gut. We performed this study describe burn patients at risk of acute mesenteric ischemia (AMI) with aim identify potential modifiable factors.Retrospective case-control adult severely burned between August 2012 and March 2017. Patients who developed AMI were matched without a ratio 1:3 (same year admission, Abbreviated Burn Severity Index [ABSI], Simplified Acute Physiology Score II [SAPSII]). Univariate multiple regression...
We determined whether an audit on the adherence to guidelines for hospital-acquired pneumonia (HAP) can improve outcomes of patients in intensive care units (ICUs).This study was conducted at 35 ICUs 30 hospitals. included consecutive, adult hospitalized 3 days or more. After a 3-month baseline period followed by dissemination recommendations, compliance recommendations (audit period) cluster-randomized trial. randomly assigned either receive and feedback (intervention group) participate...
The metabolic consequences in vivo of various balanced solutions are poorly known critically ill patients. main objective this study was to describe the Plasmalyte versus Ringer lactate (RL) burn patients, with a special focus on plasma clearance buffer anions (i.e., gluconate, acetate, and lactate). We conducted randomized trial between August 2017 October 2018 tertiary teaching hospital Paris, France. Patients total body surface area >30% were receive or RL. primary end point base...
Intravascular haemolysis has been associated with acute kidney injury (AKI) in different clinical settings (cardiac surgery, sickle cell disease). Haemolysis occurs frequently critically ill burn patients. The aim of this study was to assess the predictive value haptoglobin at admission predict major adverse events (MAKE) and AKI patients.We conducted a retrospective, single-centre cohort critical care unit tertiary centre, including all consecutive severely burned patients (total body...
To evaluate the interchangeability of oxygen consumption variations measured with Fick equation (ΔVO2Fick) and indirect calorimetry (ΔVO2Haldane) in critically ill burns patients.Prospective observational single-center study conducted a university hospital. Twenty-two consecutive patients circulatory insufficiency hyperlactatemia (>2 mmol/L) who required fluid challenge (FC) were included. All had cardiac output monitoring (transpulmonary thermodilution technique) ventilated sedated....
Patients with extensive burns are at risk of developing candidemia.To identify potentially modifiable factors and outcomes candidemia in critically ill patients.Retrospective matched cohort study including adult patients. who developed were patients Candida spp colonisation sepsis or septic shock without a ratio 1:3 (same severity scores index). Univariate multiple regression analyses performed.Of 130 severely burned least one episode shock, 14 diagnosed candidemia. In the group, had median...
We report the case of a patient with severe COVID-19 ARDS, suggesting possible therapeutic intervention by applying continuous lower abdominal compression. In order to assess ventilation distribution, lung CT scan was performed and without
We report the case of sixty-years-old men who necessitated intubation and mechanical ventilation for severe COVID-19. After 3 days under ventilation, in semi recumbent position, despite being ventilated with 5.5 ml/kg/IBW 8 cmH2O positive end expiratory pressure (PEEP), deeply sedated paralyzed, his plateau (Pplat) was markedly elevated at 41 cmH2O.