A5008840427- Veterinary Equine Medical Research
- Veterinary Pharmacology and Anesthesia
- Animal health and immunology
- Sepsis Diagnosis and Treatment
- Streptococcal Infections and Treatments
- Reproductive Physiology in Livestock
- Hemodynamic Monitoring and Therapy
- Renal function and acid-base balance
- Antibiotics Pharmacokinetics and Efficacy
- Clinical Laboratory Practices and Quality Control
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Bacterial Identification and Susceptibility Testing
- Microbial infections and disease research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Vector-Borne Animal Diseases
- Ecology and Conservation Studies
- Urological Disorders and Treatments
- Venous Thromboembolism Diagnosis and Management
- Herpesvirus Infections and Treatments
- Pleural and Pulmonary Diseases
- Veterinary Medicine and Surgery
- Botulinum Toxin and Related Neurological Disorders
- Pediatric Urology and Nephrology Studies
- Thermal Regulation in Medicine
- Congenital Diaphragmatic Hernia Studies
University of Illinois Urbana-Champaign
2015-2025
Illinois College
2003-2024
Rood and Riddle Equine Hospital
2016-2022
University of Illinois System
2012-2022
Foley Hoag (United States)
2016-2022
University of Glasgow
2020-2022
University of Prince Edward Island
2020-2022
Council of Science Editors
2020-2022
University of Veterinary Medicine
2000-2021
Purdue University West Lafayette
2021
Background The original equine sepsis score provided a method of identifying foals with sepsis. New variables associated have been evaluated, but the has not updated. Objectives To evaluate sensitivity and specificity 2 updated scores systemic inflammatory response syndrome (SIRS) criteria in regard to detecting foals. Animals Two‐hundred seventy‐three ill 25 healthy control Methods Historical, physical examination, clinicopathologic findings were used calculate scores. SIRS also evaluated....
Abstract Objective —To detect subclinical disseminated intravascular coagulation (DIC) in horses with colitis and to determine any association between the diagnosis of DIC outcome or occurrence complications colitis. Design —Prospective study. Animals —37 admitted a veterinary teaching hospital for treatment acute Procedure —Coagulation profiles were obtained on each horse 0, 24, 48 hours after admission. Six tests performed: platelet count, plasma fibrinogen concentration, prothrombin time,...
The discordance between extremely high seroprevalence of Taenia solium antibodies in disease-endemic populations, relatively few symptomatic cases neurocysticercosis, and background levels putatively inactive brain lesions (mainly calcifications) seronegative controls have confused researchers, clinicians, epidemiologists the last decade. We reviewed longitudinal serologic data from general population serosurveys 3 different areas Peru Colombia found that approximately 40% seropositive...
Abstract Case Description —5 horses were evaluated because of decreased appetite, weight loss, fever, cough, tachypnea, and respiratory distress. Clinical Findings —Tachycardia, increased effort, lethargy, poor body condition, nasal discharge detected in various combinations on initial physical examination. Evaluation the lower portion tract via radiography ultrasonography revealed a severe nodular interstitial pattern. Histologic examination lung tissue expansion alveolar parenchyma with...
Summary Background Meconium impaction/retention is a significant cause of colic in foals. Historically, limitations both medical and surgical treatment are noted. Outcomes meconium have not recently been reported. Objective To describe case characteristics outcomes foals with impaction/retention. Study design Retrospective, single referral hospital. Methods Medical records from 2006 to 2024 were searched for ≤3 days old history straining defecate, abdominal distention, colic, weakness and/or...
ABSTRACT Background Sepsis has been defined in humans as the concurrent proven or suspected presence of microbial infection and systemic inflammatory response syndrome (SIRS). is leading cause morbidity mortality neonatal foals. The clinical utility using SIRS its individual components to predict critically ill foals currently unknown. Objectives Assess ability history signalment, findings, laboratory results, SIRS‐related indices Animals Retrospective, multi‐center, cross‐sectional study a...
Summary Clinical, pathological, immunohistochemical, serological and microbiological findings are described for 2 geographically temporally distinct equine arteritis virus (EAV) epidemics in newborn foals. Outbreak A occurred at a commercial Standardbred breeding facility; B began group of research animals. Clinical signs were severe primarily referrable to the respiratory tract. Fever leucopenia and/or thrombocytopenia observed foals surviving more than 24 h. The most common gross...
Summary Reasons for performing the study: Admission L‐lactate concentration is a useful and commonly measured biomarker not previously prospectively evaluated in large multicentre study of critically ill neonatal foals. Objectives: To evaluate overall outcome association survival at admission ([LAC] ADMIT ) by periparturient history, presenting complaint clinicians' major diagnosis Methods: Thirteen university private equine referral hospitals enrolled 643 foals over 2008 foaling season....
Lactate concentration in blood or plasma ([LAC]) and change [LAC] are associated with survival sick foals.[LAC] over time at 96 hours discharge neonatal foals. Furthermore correlate culture results pressure admission.Two hundred twenty-five foals consecutively admitted to a Neonatal Intensive Care Unit.Retrospective case review. Foals <or=30 days of age from arterial (190) umbilical (35) gas analysis ([LAC](BG)) admission, 24, 48 hours. [LAC](BG), pressure, status, outcome (survival versus...
Abstract Background Prognostic indicators for equine multinodular pulmonary fibrosis (EMPF), an interstitial fibrosing lung disease, are poorly described. Hypothesis/Objectives Describe diagnostic findings and outcome predictors EMPF. Animals Forty‐six adult horses with Methods Retrospective multicenter case series from 2009 to 2019. Radiographic (n = 27) ultrasonographic studies 19) EMPF bronchoalveolar lavage fluid (BALF) cytology 6 13 asthma cases were independently reviewed blinded...
Abstract Background Polycythaemia and coagulopathy are identified risk factors for non‐survival in critically ill horses. Assessment of coagulation is recommended critical care monitoring but may be affected by concurrent polycythaemia. Objective To evaluate the effects induced polycythaemia on parameters as measured a point‐of‐care viscoelastic device (VCM Vet™). Study design Prospective interventional study. Methods Healthy adult horses ( n = 7) were given 6 mcg/kg phenylephrine IV over 15...
Background : Blood lactate concentration [LAC] is considered a useful indicator of disease severity in horses. Agreement point‐of‐care (POC) monitors with laboratory standards has not been established for clinically abnormal Hypothesis It was hypothesized that results from POC monitor would be agreement laboratory‐based measurement [LAC]. Animals The study included adult horses presented emergency evaluation. Methods A prospective observational performed. measured whole blood (AWB) and...
Coagulopathy is a potentially underrecognized complication of sepsis and septic shock in critically ill neonatal foals.Critically foals have abnormalities coagulation that are associated with disease severity outcome.Foals <72 hours old admitted to intensive care unit.Prospective, observational study. Blood was collected at admission, 24, 48 for platelet count, prothrombin time, activated partial thromboplastin antithrombin activity concentrations fibrin degradation products, fibrinogen...
In several species, there is a strong correlation between indicators of red cell mass (RCM) and thromboelastometry results. The horse has reliable, temporary, polycythemia in response to phenylephrine infusion. Our objective was evaluate the effects an in-vivo increase circulating RCM on results equine model transient polycythemia. Six healthy research horses had whole blood with contact activator tissue factor initiation after recalcification citrated samples. Additional samples were frozen...
Evaluation of serial blood lactate concentrations [LAC] are prognostic value for morbidity and mortality in critically ill human patients neonatal foals, but have not been prospectively evaluated a large multicentre study foals. To evaluate the sequential analysis foals with risk mortality. Prospective, observational study. Thirteen university private equine referral hospitals enrolled 643 over 2008 foaling season was measured at admission ([LAC]ADMIT ) 24 ([LAC]24 ), 48 ([LAC]48 72 ([LAC]72...
Background: Blood lactate concentration [LAC] is considered a useful indicator of disease severity in horses. Agreement point-of-care (POC) monitors with laboratory standards has not been established for clinically abnormal Hypothesis: It was hypothesized that results from POC monitor would be agreement laboratory-based measurement [LAC]. Animals: The study included adult horses presented emergency evaluation. Methods: A prospective observational performed. measured whole blood (AWB) and...
Abstract Objective – To determine if changes in viscoelastic variables are associated with abnormalities observed the standard coagulation profile and patient outcome foals suspected septicemia. Design Prospective clinical trial during 2003 2004 foal season. Setting Neonatal intensive care unit at a veterinary teaching hospital. Animals Thirty critically ill <72‐hour‐old admitted sequentially meeting criteria for systemic inflammatory response infection. Interventions Hemostatic...
Abstract Objective – To investigate the association between blood lactate concentration, measured at admission and following 12–36 hours of treatment, age, diagnosis, survival in neonatal foals. Design Retrospective, observational study. Setting Two equine referral hospitals. Animals One hundred twelve foals ≤96 age were included. Interventions Arterial or venous samples obtained from all surviving hours. Measurements The concentration (LAC) was recorded 2 time points: (LAC‐Admission)...
Inflammatory airway disease has a high prevalence in horses, but is often diagnostic challenge. Flowmetric plethysmography and histamine bronchoprovocation (FP/HBP) simple effective tool for diagnosis, reproducibility of these measurements made over time not been established.We hypothesize that the measurement responsiveness horses using FP/HBP consistent both short long periods time.Twenty-nine healthy adult from 2 university herds.In this prospective experimental study, was determined each...
Summary Reasons for performing study : The incidence and implications of positive blood cultures in mature horses with diarrhoea is unknown. diagnosis bacteraemia may alter treatment prognosis. Hypothesis proportion that are culture higher than previously assumed a has negative impact on survival. Methods Blood were taken at admission 24 h after from 31 diarrhoea. Results Nine (29%) within admission. Organisms isolated included Corynebacterium spp. (n = 6), Streptococcus 2), Pantoea...