A5026487778- Veterinary Equine Medical Research
- Reproductive Physiology in Livestock
- Animal Virus Infections Studies
- Animal health and immunology
- Body Composition Measurement Techniques
- Veterinary Orthopedics and Neurology
- Hemodynamic Monitoring and Therapy
- Infectious Diseases and Mycology
- Helminth infection and control
- Congenital Anomalies and Fetal Surgery
- Actinomycetales infections and treatment
- Urological Disorders and Treatments
- Thermoregulation and physiological responses
- Viral gastroenteritis research and epidemiology
- Veterinary Oncology Research
- Hepatitis B Virus Studies
- Cardiac Arrest and Resuscitation
- Cancer-related molecular mechanisms research
- Electrical and Bioimpedance Tomography
- Herpesvirus Infections and Treatments
- Ultrasound in Clinical Applications
- Preterm Birth and Chorioamnionitis
- Plant and fungal interactions
- Infective Endocarditis Diagnosis and Management
- Tracheal and airway disorders
University of Kentucky
2020-2024
Iowa State University
2017-2024
University of California, Davis
2005-2020
New York State College of Veterinary Medicine
2013-2020
Cornell University
2013-2020
University of Tennessee at Knoxville
2020
Veterinary Medical Teaching Hospital
2011
Massey University
2011
United States Food and Drug Administration
1980
Background The original equine sepsis score provided a method of identifying foals with sepsis. New variables associated have been evaluated, but the has not updated. Objectives To evaluate sensitivity and specificity 2 updated scores systemic inflammatory response syndrome (SIRS) criteria in regard to detecting foals. Animals Two‐hundred seventy‐three ill 25 healthy control Methods Historical, physical examination, clinicopathologic findings were used calculate scores. SIRS also evaluated....
Background Three flaviviruses (equine pegivirus [EPgV]; Theiler's disease–associated virus [TDAV]; non‐primate hepacivirus [NPHV]) and equine parvovirus (EqPV‐H) are present in blood products; the TDAV, NPHV, EqPV‐H have been suggested as potential causes of serum hepatitis. Objective To determine prevalence these viruses horses with Animals Eighteen diagnosed hepatitis, enrolled from US referral hospitals. Methods In prospective case study, liver, serum, or both samples were tested for...
Objective—To evaluate selected hemodynamic, blood gas, and biochemical responses to mild moderate acute loss in standing, awake horses. Design—Prospective study. Animals—7 healthy mares. Procedures—Each horse was restrained standing stocks, its head maintained a neutral position; sedatives tranquilizers were not administered. During 1-hour period, collected into collection bags by use of suction pump. The rate approximately 16 mL/kg/h (7.3 mL/lb/h). Thirty minutes after collection, the...
Abstract Objective —To assess data regarding clinical features, clinicopathologic and blood gas variables, outcome from horse mule foals with confirmed neonatal isoerythrolysis (NI). Design —Retrospective case series. Animals —17 1 foals. Procedure —Medical records of (< 14 days old) NI were reviewed. Information collected included signalment; examination findings; results hematologic, serum plasma biochemical, venous analyses urinalysis; treatments; outcome. Results —Data 17 foal (mean...
Abstract Objective —To compare clinical, microbiologic, and clinicopathologic findings among horses infected with Clostridium difficile that had toxin A in their feces, evidence of C infection were negative for diarrhea infection. Design —Cross-sectional study. Animals —292 foals diarrhea. Procedures —Feces submitted microbial culture tested the antigen glutamate dehydrogenase a commercial ELISA. Results —Horses feces higher band neutrophil count, rectal temperature, hospitalization time...
Nasal encephaloceles (meningoceles or meningoencephaloceles) are rare and not reported to be infected coupled with a facial deformity in dogs. This report describes an older dog acute worsening of seizures due suppurative meningoencephalitis coexisting rhinitis infection meningoencephalocele. Additionally, the had for at least 5 years. The results necropsy, computed tomography, postmortem magnetic resonance imaging compared. development nasal is discussed, including potential role early...
Azithromycin is widely used in foals but has not been studied adult horses. The goals of this study were to determine the pharmacokinetic profile and make a preliminary assessment safety azithromycin was administered intravenously (5 mg/kg) intragastrically (10 six healthy mares crossover design. Serial plasma samples, blood neutrophils, pulmonary macrophages collected for measurement concentrations. also orally once day 5 days five evaluation bioavailability following intragastric...
A newborn foal was presented because it unresponsive and in cardiopulmonary arrest. Aggressive cerebral resuscitation administered to the foal, which revived foal; however, acute renal failure developed. Fluid retention azotemia occurred although alert able suckle. 6-hour replacement therapy session using hemodiafiltration a continuous machine at 3 days of age lowered foal's facilitated removal some excess body fluid. Despite therapy, developed pulmonary edema euthanized. Although this case...
The characteristics, history, clinical signs, treatment and outcome of nine horses with abscesses caused by Actinomyces species were reviewed. dna sequencing was used to determine the one isolates. 11 years age, most commonly located in submandibular retropharyngeal regions. bacterium usually cultured as sole isolate often affected autumn. Most treated antimicrobials drainage, but some them recurred. had residual scar tissue that cases did not resolve.
Multi-frequency bioelectrical impedance analysis (MF-BIA) has been used to evaluate extracellular fluid volume (ECFV), but not fluxes associated with or furosemide administration in horses. If able detect acute changes ECFV, MF-BIA would be useful monitoring therapy horses.The purpose of this study was the ability compartment We hypothesized that clinically relevant (10-20%) ECFV.Six healthy mares were study.This is an original experimental study. Mares studied 3 experiments: (1) crystalloid...
Abstract Objective —To apply the principle of sodium dilution to calculate changes in extracellular fluid (ECF) volume (ECFV) and intracellular (ICFV) that occur during dehydration rehydration horses. Animals —8 healthy horses various breeds. Procedures —Horses were dehydrated over 4 hours by withholding water administering furosemide. Saline (0.9% NaCl) solution was administered IV next 2 (20 mL/kg/h; total 40 mL/kg). Horses monitored for an additional hour following administration. Initial...
A study was performed by 15 collaborators on a method for the extraction and chromatographic separation of Staphylococcus aureus enterotoxins from foods. Enterotoxin types A--E were added to crabmeat, milk, ground beef, potato. Evaluation based solubility food eluates after enterotoxin; efficiency recovery foods; serological categorizing foods, as determined presence or absence in 8 samples studied. The collaborative results sample solubility, detection identification enterotoxin...
Background : Multi‐frequency bioelectrical impedance analysis (MF‐BIA) has been used to evaluate extracellular fluid volume (ECFV), but not fluxes associated with or furosemide administration in horses. If able detect acute changes ECFV, MF‐BIA would be useful monitoring therapy Hypothesis The purpose of this study was the ability compartment We hypothesized that clinically relevant (10–20%) ECFV. Animals Six healthy mares were study. Methods This is an original experimental Mares studied 3...
A 9-year-old Quarter Horse gelding was presented for lethargy, decreased appetite, polyuria and polydipsia (PU/PD), severe muscle wasting suggestive of immune-mediated myositis.The horse displayed fever, tachyarrhythmia, inappetence, PU/PD, epaxial gluteal wasting. Clinicopathologic findings were consistent with previously reported cases systemic calcinosis in horses, including increased enzyme activity, hyperphosphatemia, calcium-phosphorus product, hypoproteinemia, an inflammatory...
Equine premature placental separation (PPS) is poorly understood and represents an important risk factor for fetal/neonatal hypoxia.To examine transcriptomic changes in the chorioallantois (CA) from mares with clinical PPS compared CA normal foaling mares. Differential gene expression was determined ontology as well molecular pathways related to were characterised.Retrospective case: control study.CA collected Thoroughbred a history of (n = 33) 4) parturition examination transcriptional...
Ferret systemic coronaviral disease (FSCD) is a well-established cause of mortality in domestic ferrets. We describe herein novel findings case FSCD that was diagnosed and medically managed following virus detection by immunohistochemical (IHC) staining surgical biopsy samples. Hematologic changes this ferret suggested spread the to bone marrow, which confirmed IHC postmortem sample. Genotyping indicated grouped with alphacoronaviruses most closely related enteric coronavirus (FRECV) MSU-2....
Cervical remodeling is a critical component in both term and preterm labor eutherian mammals. However, the molecular mechanisms underlying cervical remain poorly understood mare. The current study compared transcriptome of equine cervix (cervical mucosa (CM) stroma (CS)) during placentitis (placentitis group, n = 5) normal prepartum mares (prepartum 3) to pregnant (control 4). Transcriptome analysis identified differentially expressed genes (DEGs) (5310 CM 907 CS) period (189 78 CS). Our...