In this communication, an electronically reconfigurable folded reflectarray antenna (ERFRA), which includes $14 \times 14$ reflecting elements and features a fully planar compact configuration wide-angle beam-scanning performance, was developed, fabricated, tested. A novel element that is able to carry out cross-polarization rotation 1 bit compensation phases first developed. After experimentally demonstrating its feasibility, the new then applied design of ERFRA, with feed in center...

M2 macrophage-mediated tissue repair plays an important role in acute myocardial infarction (AMI).Additionally, VSIG4, which is mainly expressed on tissue-resident and macrophages, crucial for the regulation of immune homeostasis; however, its effects AMI remain unknown.In this study, we aimed to investigate functional significance VSIG4 using knockout adoptive bone marrow transfer chimeric models.We also determined function cardiac fibroblasts (CFs) through gain-or loss-of-function...

In this paper, a fully electronically reconfigurable reflectarray antenna that has 14×14 reflecting elements and features higher aperture efficiency was designed, fabricated, tested. A new configuration of the element first developed so all bias circuit PIN diode are arranged on opposite side surface, avoiding potential unexpected reflection aiming at improvement efficiency. The element, which smaller size (0.365λ), then applied to design 14 × antenna. field programmable gate array...

Atherosclerosis is an inflammatory disease that associated with monocyte recruitment and subsequent differentiation into lipid-laden macrophages at sites of arterial lesions, leading to the development atherosclerotic plaques. PLC a key member signaling pathways initiated by G protein–coupled ligands in macrophages. However, role this enzyme regulation macrophage function not known. Here, we studied from mice lacking β2, β3, or both isoforms found β3 major functional β isoform murine...

Electric stimulation has been proved to be available monitor the efficacy of renal denervation (RDN). This study was evaluate effectiveness high-frequency (HFS)-guided proximal RDN.A total 13 Chinese Kunming dogs were included and allocated RDN group (n=8) control (n=5). HFS (20 Hz, 8 V, pulse width 2 ms) performed from distal artery in all dogs. Radiofrequency ablations delivered only at positive sites where systolic blood pressure (BP) increased ≥10 mm Hg during HFS. Postablation over...

Abstract Background non-rheumatic calcific aortic valve disease (nrCAVD) is a valvular characterized by progressive calcification of the that can lead to left heart failure and death. This study reports on global burden CAVD, utilizing all available data using Global Burden Disease (GBD) methodology understand epidemiology this widely prevalent disease. Methods Prior current effort, CAVD was included in GBD as non-specific contributor “valvular disease” burden. In study, distinguished its...

The aim of this study was to investigate the relationship between quantitative flow ratio (QFR) after drug-coated balloon (DCB) treatment for in-stent restenosis (ISR) and neointimal characteristics assessed by optical coherence tomography (OCT) clinical outcomes. This single-center, retrospective, observational cohort included ISR patients who underwent DCB angioplasty under OCT guidance. primary outcome a target vessel failure (TVF), defined as composite endpoint cardiovascular death,...

ABSTRACT Background Coronary artery plaque rupture (PR) is closely associated with immune‐inflammatory responses. The systemic inflammatory index (SII) and the response (SIRI) have shown potential in predicting occurrence of PR. Objective This study aims to establish a machine learning (ML) model that integrates baseline patient characteristics, SII, SIRI predict goal identify high‐risk PR patients before intravascular imaging examinations. Methods We included 337 acute coronary syndrome who...

Ovarian cancer is a highly aggressive and deadly disease. Currently, the treatment for ovarian entails cytoreductive surgery followed by chemotherapy, mainly cisplatin or carboplatin combined with paclitaxel. Although this regimen initially effective in high percentage of cases, unfortunately, after few months initial treatment, tumor relapse occurs due to platinum-resistance. DOXIL (liposomal preparation doxorubicin) choice drug recurrent cancer. However, its response rate very low...

Methods: RPM was prepared through an oil-in-water emulsion solvent evaporation method, and combined with BHA/PAA to obtain drug-loaded, slow-releasing materials. Twenty-six New Zealand white rabbits were induced establish the animal model of chronic osteomyelitis. After debridement, animals randomly divided into three groups (n=8): experimental group (with RPM-loaded BHA/PAA), control blank group. The evaluated for antibacterial activity, dynamics drug release, osteogenic ability in vitro...

Abstract Matrine is a main active constituent of Chinese herb Sophora flavescens Ait (Kushen), which has shown various pharmacological effects, and been reported to exhibit protective effects in heart failure. In the present study, underlying mechanism matrine was explored H2O2-induced H9c2 cell line. It confirmed that could alleviate injury cells. And down-regulation long non-coding RNA HOTAIR induced by H2O2 be reversed treating with matrine. Moreover, overexpression promoted viability...

Innate γδ T cells play critical roles in mucosal immunity such as regulating intestinal epithelial homeostasis. In addition, are significantly increased the inflamed mucosa of patients with ulcerative colitis. However, a heterogeneous population. IL-17-producing versus IFNγ-producing differential different disease settings. Therefore, dissecting exact role subsets colitis is essential for understanding immunopathogenesis. current study, we found that TCR δ-deficient mice had more severe...

Abstract Most high‐efficiency polarization converters in literatures are based on reflective structures. Here we report the designs and experiments of transmissive using novel compact frequency‐selective surfaces (FSSs). By combining common dipole square ring band‐pass FSSs, a FSS can be generated, whose pass bands phases for two orthogonal polarizations tuned by changing dimensions structure. As demonstrations concept, cross converter (a half‐wave plate) linear‐to‐circular (LP‐CP)...

Atrial fibrosis is an important factor in initiating and maintaining atrial fibrillation. The purpose of this study was to test the hypothesis that angiotensin-converting enzyme-2 (ACE2) overexpression might inhibit collagen accumulation improve remodeling a canine pacing model.Thirty-two mongrel dogs both genders were divided randomly into 4 groups: sham-operated, control, gene therapy with adenovirus-enhanced green fluorescent protein (Ad-EGFP), Ad-ACE2. All Ad-EGFP, Ad-ACE2 groups paced...

This study investigates Al-Mg2Si-Si alloy joints produced via resistance spot welding (RSW) with and without the use of Al-Si interlayers. The joint microstructures both interlayers consist three zones: base material (BM), heat affected zone (HAZ) weld nugget (WN). WN is oval, increases in current increase size methods. RSW an interlayer have larger WNs than those under same conditions. Relationships between are established by Gaussian fitting Lorentz fitting. A comparison two approaches...

Heart failure (HF) has been proposed as a potential indication of renal denervation (RDN). However, the mechanisms enabling RDN to attenuate HF are not well understood, especially central effects RDN. The aim this study was decipher mode operation in treatment using canine model right ventricular rapid pacing-induced heart failure. Accordingly, 24 Chinese Kunming dogs were randomly grouped receive sham procedure (Sham-operated group), bilateral (RDN pacing induce (HF-control and plus (RDN+HF...

Abstract This paper presents a wideband high‐gain dual‐circularly‐polarized (CP) antenna with simple configuration. Instead of improving the gain using dual‐CP element array, Fabry‐Perot resonator concept is applied in this work. By designing dual‐linearly‐polarized and linear‐to‐circular polarization (LP‐CP) metasurface polarizer separately combining them, can be achieved. Structural simplicity less design difficulty are advantages design. Experimental results validate concept. It exhibits...

In recent years, researches on Electrical Discharge Machining (EDM) plasma mainly focus the reasons and characteristics of oscillation discharge wave oscillation. The mechanism EDM channel oscillation, however, has not been explained in detail. This paper chiefly analyzes geometry change gap, diameter electromagnetic field plasma. These three factors contribute to after affected by one another. On base analyzing, a new method machining active-oscillation-pulse put forward....

Cardiac macrophages with different polarization phenotypes regulate ventricular remodeling and neovascularization after myocardial infarction (MI). Annexin A2 (ANXA2) promotes macrophage to the repair phenotype regulates neovascularization. However, whether ANXA2 plays any role in post-MI its underlying mechanism remains obscure. In this study, we observed that expression levels of were dynamically altered mouse hearts upon MI peaked on second day post-MI. Using adeno-associated virus...

This paper presents a novel multibeam fully-planar folded transmitarray antenna (FTA) for massive MIMO applications. The FTA is composed of planar metasurface-based transmitarray, reflectarray and five small identical feeders. Both are able to twist the polarization incoming electromagnetic (EM) waves 90° while could also provide transmission compensation phase at same time. A example designed simulated. results successfully demonstrate functionality, with appropriate aperture efficiency...

<title>Abstract</title> The aim of this study was to investigate the relationship between quantitative flow ratio (QFR) after drug-coated balloon (DCB) treatment for in-stent restenosis (ISR) and neointimal characteristics assessed by optical coherence tomography (OCT) clinical outcomes. This single-center, retrospective, observational cohort included ISR patients who underwent DCB angioplasty under OCT guidance. primary outcome a patient-oriented composite endpoint (POCE), defined as...

To fully leverage the potential flexibility resources of a source-network-load-storage (SNLS) system and achieve green transformation multi-source systems, this paper proposes an economic low-carbon operation strategy for SNLS system, considering joint ladder-type certificate trading (GCT)–carbon emission (CET), integrated demand response (IDR). Firstly, focusing on load side electricity–heat–cooling–gas coupling, comprehensively considers three types flexible loads: transferable,...