Chaoxue Zhang

ORCID: 0000-0002-3037-8819
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About
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Research Areas
  • Radiomics and Machine Learning in Medical Imaging
  • Liver Disease Diagnosis and Treatment
  • MRI in cancer diagnosis
  • Thyroid Cancer Diagnosis and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • AI in cancer detection
  • Liver Disease and Transplantation
  • Ultrasound Imaging and Elastography
  • Photoacoustic and Ultrasonic Imaging
  • Ultrasound and Hyperthermia Applications
  • Congenital Heart Disease Studies
  • Reproductive Biology and Fertility
  • Organ Transplantation Techniques and Outcomes
  • Tracheal and airway disorders
  • Ultrasonics and Acoustic Wave Propagation
  • Ovarian cancer diagnosis and treatment
  • Cleft Lip and Palate Research
  • Endometrial and Cervical Cancer Treatments
  • Fetal and Pediatric Neurological Disorders
  • Advanced X-ray and CT Imaging
  • Renal cell carcinoma treatment
  • Hepatitis B Virus Studies
  • Intestinal Malrotation and Obstruction Disorders
  • Thyroid and Parathyroid Surgery
  • Cardiovascular Disease and Adiposity

First Affiliated Hospital of Anhui Medical University
2010-2025

Anhui Medical University
2013-2025

Wannan Medical College
2024

East China Normal University
2024

Abstract Background Patients with alpha-fetoprotein (AFP)-positive hepatocellular carcinoma (HCC) have aggressive biological behavior and poor prognosis. Therefore, survival time is one of the greatest concerns for patients AFP-positive HCC. This study aimed to demonstrate utilization six machine learning (ML)-based prognostic models predict overall Methods Data on HCC were extracted from Surveillance, Epidemiology, End Results database. Six ML algorithms (extreme gradient boosting...

10.1186/s12967-024-05203-w article EN cc-by Journal of Translational Medicine 2024-05-13

Berry syndrome is a rare combination of cardiac malformations, which characterized by the following including aortopulmonary window, aortic right pulmonary origin, interrupted arch or hypoplastic coarctation aorta, and an intact ventricular septum. There are few reviews on prenatal diagnosis fetal echocardiography. We used sequential cross-sectional scanning from apex to bottom heart find arch. This process like opening Chinese scroll painting, picture gradually extends reveal whole picture....

10.1097/ruq.0000000000000700 article EN Ultrasound Quarterly 2025-01-21

A large percentage of patients undergoing esophagogastroduodenoscopy (EGD) screening do not have esophageal varices (EV) or only small EV. We evaluated a large, international, multicenter cohort to develop novel score, termed FIB-4plus, by combining the fibrosis-4 (FIB-4) liver stiffness measurement (LSM), and spleen (SSM) identify high-risk EV (HRV) in compensated cirrhosis. This international study involved with cirrhosis from 17 Chinese hospitals one Croatian institution (NCT04546360)....

10.3350/cmh.2024.0898 article EN cc-by-nc Clinical and Molecular Hepatology 2025-02-05

Abstract Background To develop a model based on intra- and peritumoral radiomics features derived from B-mode ultrasound (BMUS), strain elastography (SE), shear wave (SWE) for cervical lymph node metastasis (LNM) prediction in papillary thyroid cancer (PTC) to determine the optimal size. Methods PTC Patients were enrolled two medical centers. Radiomics extracted intratumoral four regions with widths of 0.5–2.0 mm tri-modality (US) images. Boruta algorithm XGBoost classifier used selection...

10.1186/s40644-025-00832-w article EN cc-by Cancer Imaging 2025-02-13

Objectives This study aimed to explore the performance of a model based on Chinese Thyroid Imaging Reporting and Data Systems (C-TIRADS), clinical characteristics, other ultrasound characteristics for prediction Bethesda III/IV thyroid nodules before fine needle aspiration (FNA). Materials methods A total 855 from 810 patients were included. All underwent examination FNA. categorized according C-TIRADS criteria classified into two groups, non-III/IV nodules, using cytologic diagnosis as gold...

10.3389/fendo.2025.1442575 article EN cc-by Frontiers in Endocrinology 2025-03-03

Abstract Predicting low nuclear grade DCIS before surgery can improve treatment choices and patient care, thereby reducing unnecessary treatment. Due to the high heterogeneity of limitations biopsies in fully characterizing tumors, current diagnostic methods relying on invasive face challenges. Here, we developed an ensemble machine learning model assist preoperative diagnosis DCIS. We integrated clinical data, ultrasound images, mammography Radiomic scores from 241 cases. The model, based...

10.1038/s41598-025-92080-y article EN cc-by Scientific Reports 2025-03-03

ObjectivesWhile several indicators have been studied, the association of body roundness index (BRI) with non-alcoholic fatty liver disease (NAFLD) remains unclear. We aimed to explore between BRI and ultrasound-defined NAFLD.MethodsThe sample dataset was extracted from National Health Nutrition Examination Survey (NHANES) during period 2017–2018. The diagnosis NAFLD determined based on controlled attenuated parameter (CAP≥248 dB/m) score ultrasound transient elastography (LUTE). Participants...

10.1016/j.heliyon.2023.e23429 article EN cc-by-nc-nd Heliyon 2023-12-10

Introduction: To explore whether ultrasonic radiomics extracted by machine learning method can noninvasively evaluate lupus nephritis (LN) activity. Materials and Methods: This retrospective study included 149 patients with LN diagnosed renal biopsy. They were divided into a training cohort (n=104) test (n=45). Ultrasonic features from the ultrasound images, constructed. Furthermore, five algorithms compared to The performance of binary classification model was evaluated area under receiver...

10.2147/jir.s398399 article EN cc-by-nc Journal of Inflammation Research 2023-02-01

Coherent plane-wave compounding (CPWC) is an effective method to improve the image quality of ultrasound imaging (PWI), which coherently sums delay-and-sum (DAS) beamforming outputs PWI at different steering angles. However, due data-independent nature, DAS obtains limited resolution and contrast. Therefore, various adaptive methods have been presented achieve improved quality. In this paper, weighting factor named normalized autocorrelation (NAF), derived by function (NACF), proposed for...

10.1109/access.2018.2852641 article EN cc-by-nc-nd IEEE Access 2018-01-01

Distinguishing the degree of differentiation, hepatocellular carcinoma (HCC) has important clinical significance in therapeutic decision-making and patient prognosis evaluation.We developed a deep-learning radiomics (DLR) model based on contrast-enhanced ultrasound (CEUS) to evaluate differentiation HCC noninvasive. We retrospectively analyzed patients who had undergone resection CEUS one week preoperatively between November 2015 August 2022. Enrolled were randomly divided into training...

10.2147/jhc.s400166 article EN cc-by-nc Journal of Hepatocellular Carcinoma 2023-02-01

Abstract Background In terms of embryonic origin, vascular ring is a congenital anomaly in which the aortic arch and its branches completely or incompletely encircle compress trachea esophagus. Early accurate diagnosis key to treatment. Prenatal mainly relies on fetal echocardiography, but rate missed misdiagnosis still very high, prognosis has not been evaluated. The aim this study was investigate accuracy prenatal evaluate semi-quantitatively according shape distance between vessel...

10.1186/s12884-023-05637-y article EN cc-by BMC Pregnancy and Childbirth 2023-05-02

Abstract Testicular microcirculation is closely related to spermatogenic function and seminiferous tubular function. The diagnosis monitoring of testicular diseases can be associated with microcirculation; however, there are currently no effective non‐invasive methods for super‐resolution imaging microcirculation. In this study, we introduced state‐of‐the‐art graph‐based tracking the Kalman motion model algorithm non‐invasively image human first time a regular frame‐rate clinical ultrasound...

10.1002/viw.20230093 article EN cc-by View 2024-01-11

Objective This paper aims to investigate clinical value of intrahepatic and intra-stent hemodynamic changes after transjugular portosystemic shunt (TIPS), by using color Doppler ultrasound during the diagnosis hepatic encephalopathy (HE) in patients with hepatitis B cirrhosis.Methods A retrospective analysis cirrhotic portal hypertension, who underwent TIPS The First Affiliated Hospital Anhui Medical University from January 2018 2021, was conducted. 22 developed HE within 3 months comprised...

10.1080/00365521.2022.2029938 article EN Scandinavian Journal of Gastroenterology 2022-01-29

Background: Breast cancer is the most common tumor globally.Automated Volume Scanner (ABVS) and strain elastography (SE) can provide more useful breast information.The use of radiomics combined with ABVS SE images to predict has become a new focus.Therefore, this study developed validated analysis lesions in combination coronal plane improve differential diagnosis benign malignant diseases.Patients Methods: 620 pathologically confirmed from January 2017 August 2021 were retrospectively...

10.2147/bctt.s410356 article EN cc-by-nc Breast Cancer Targets and Therapy 2023-05-01

Free portal pressure measurement is a reliable method for assessment of in patients with cirrhosis. Intrahepatic circulatory time analysis sonographic contrast agent can assess liver fibrosis and its severity. The purposes this pilot study were to the correlation between intrahepatic free whether be used predict venous severity.The measured 31 hepatitis B virus-related disease. Pearson was pressure.The hepatic vein-hepatic artery interval times significantly shorter hypertension group than...

10.7863/jum.2011.30.2.205 article EN Journal of Ultrasound in Medicine 2011-02-01

To investigate the performance of a radiomics model based on gray-scale ultrasonography (US) for preoperative non-invasive prediction ipsilateral axillary lymph node (ALN) metastasis in patients with breast cancer (BC).A total 192 pathologically confirmed BC were included this study. The training set was comprised 132 from hospital 1 and test 60 2. All underwent US before percutaneous core biopsy results ALN status reported by radiologist 12 years experience recorded. Radiomic features...

10.21037/gs-21-315 article EN Gland Surgery 2021-06-01
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