A5102818101- Sinusitis and nasal conditions
- Epigenetics and DNA Methylation
- Cancer-related gene regulation
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- IL-33, ST2, and ILC Pathways
- Advanced battery technologies research
- Advanced Battery Materials and Technologies
- RNA and protein synthesis mechanisms
- Biochemical and Structural Characterization
- Bacterial Identification and Susceptibility Testing
- RNA modifications and cancer
- Immune Response and Inflammation
- ATP Synthase and ATPases Research
- Colorectal Cancer Treatments and Studies
- Inflammasome and immune disorders
- Traditional Chinese Medicine Studies
- Immune cells in cancer
- Bacteriophages and microbial interactions
- Advanced Battery Technologies Research
- RNA Research and Splicing
- Urologic and reproductive health conditions
- Bacterial Genetics and Biotechnology
- Vibrio bacteria research studies
Wuhan University
2022-2024
Renmin Hospital of Wuhan University
2022-2024
Shenzhen University
2023-2024
Anhui Agricultural University
2024
Peking Union Medical College Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Eye & ENT Hospital of Fudan University
2024
Xinzhou Teachers University
2024
Zhengzhou University
2024
Hunan Normal University
2024
Abstract Background Tumor cell expression of Toll-like receptors (TLRs) can promote inflammation and survival in the tumor microenvironment. receptor 4 (TLR4) signaling cells mediate immune escape progression, it is regarded as one mechanisms for chronic tumorigenesis progression. The TLR4 human breast cancer line MDA-MB-231 its biological function development progression have not been investigated. We sought to characterize TLR1-TLR10 established MDA-MB-231, investigate roles growth,...
Abstract Zn interfacial issues involved dendrite evolution and undesired parasitic reactions are tough challenges to impede the progress of ion battery. Herein, dendrite‐free anode with boosted stability is achieved by four‐in‐one functional additive triethyl phosphate (TEP). Experiments theoretical calculation reveal that TEP participates in generation compact inorganic interface prevent from corrosion. Meanwhile, electrical double layer (EDL) reconstructed adsorbed molecules inner weakened...
Staphylococcus aureus is a common pathogen causing both hospital and community-acquired infections. Hemolysin one of the important virulence factors for S. causes typical β-hemolytic phenotype which called complete hemolytic as well. Recently, with an incomplete (SIHP) was isolated from clinical samples. To study microbiologic characteristics SIHP, special SIHP verified on sheep blood agar plates supplied by different manufacturers. Expression hemolysin genes hla, hlb, hlgC, hld detected...
Abstract Background Airway inflammation is the core pathological process of asthma, with key inflammatory regulators incompletely defined. Recently, fibroblast growth factor 2 (FGF2) has been reported to be an regulator; however, its role in asthma remains elusive. This study aimed investigate immunomodulatory FGF2 asthma. Methods First, expression was characterised clinical samples and house dust mite (HDM)-induced mouse chronic model. Second, recombinant (rm-FGF2) protein intranasally...
Abstract The application of zinc‐ion batteries (ZIBs) is seriously challenged by the poor stability Zn anode and cathode in aqueous solution, which closely associated with electrolyte structure water reactivity. Herein, issues both for can be simultaneously addressed via tuning solvation hybrid tripropyl phosphate (TPP) as co‐solvent. On anode, a robust poly‐inorganic solid interphase (SEI) layer comprised 3 (PO 4 ) 2 ‐ZnS‐ZnF species situ formed, effectively suppressing parasitic reaction...
Chronic rhinosinusitis with nasal polyps (CRSwNP) is caused by prolonged inflammation of the paranasal sinus mucosa. The epithelial to mesenchymal transition (EMT) involved in occurrence and development CRSwNP. T-cell immunoglobulin domain mucin 4 (TIM-4) closely related chronic inflammation, but its mechanism CRSwNP poorly understood. In our study, we found that TIM-4 was increased sinonasal mucosa patients and, especially, macrophages. positively correlated α-SMA negatively E-cadherin CRS....
Background: Ferroptosis is a form of programmed cell death triggered by iron-dependent lipid peroxidation, characterized iron accumulation and elevated reactive oxygen species (ROS), leading to membrane damage. It associated with variety diseases. However, the cellular molecular links between ferroptosis, immune inflammation, brain-peripheral blood axis in Alzheimer's disease (AD) remain unclear. Methods: We integrated bulk RNA-seq data from AD brain tissue peripheral refined screening...
Chronic rhinosinusitis with nasal polyps (CRSwNP) can be classified into eosinophilic CRSwNP (eCRSwNP) and non-eosinophilic (non-eCRSwNP) by tissue biopsy, which is difficult to perform preoperatively. Clinical biomarkers have predictive value for the classification of CRSwNP. We aimed evaluate application artificial neural network (ANN) modeling in distinguishing different endotypes based on clinical biomarkers.Clinical parameters were collected from 109 patients, their ability was...
To investigate the clinical effects of mindfulness-based stress reduction (MBSR) intervention combined with early cardiac rehabilitation (CR) on patients acute myocardial infarction (AMI) assisted an intra-aortic balloon pump (IABP).A total 100 AMI IABP assistance due to hemodynamic instability at Wuhan Asia Heart Hospital were enrolled in study. The participants divided into two groups using random number table method (n = 50 each group). Patients receiving routine CR assigned control...
Staphylococcus aureus (S. aureus) is an important human pathogen, which commonly causes the acquired infectious diseases in hospital and community. Effective simple antibiotic treatment against S. aureus-related disease becomes increasingly difficult. Developing a safe effective vaccine has become one of world's hot spots once again. The key issue developing how to find ideal pathogenic gene aureus. It was previously suggested that EsxA might be very factor abscess formation mice, but...
Purpose: To investigate the correlation between traditional Chinese medicine (TCM) constitution and pregnancy outcomes in elderly primiparae.Methods: A cross-sectional case-control study was conducted on 113 primiparae who were delivered Jinshan Hospital of Fudan University, Shanghai, China from January 2019 to December 2019. The group. Using a random ratio 1:3, 393 primiparous women suitable age hospital at same period selected as control questionnaire used collect clinical data,...
Duck adenovirus Type 3 (DAdV-3) severely affects the health of ducks; however, its pathogenicity in chickens remains unknown. The objectives this study were to evaluate and major pathological changes caused by DAdV-3 chickens. Viral DNA was extracted from liver Muscovy duck,
Abstract The rise of the Internet has brought about a rapid growth unstructured data recorded in form text and audio. Two key techniques that can be used to process are proposed this study, which applies deep learning processing. First, transformer feature extractor is characterize dynamic word vectors. Then, MCNN neural network combined with it perform information screening construct classification model based on transformer. features extracted from BERT input into VAEGRU module,...
Allergic rhinitis (AR) represents a hallmark of obvious hypersensitivity with an imbalance immune responses, including abnormal macrophage activity in local tissues. It has been reported that alternatively activated macrophages (M2) may contribute to allergic pathogenesis. Ten-eleven translocation (Tet) enzymes can oxidize 5-methylcytosine (m5C) mRNA, implying the epigenetic regulation post-transcriptional RNA modification. Our previous study suggested decreased Tet2 impairs function...
Fowl adenovirus serotype 4 (FAdV-4) is the main causative agent of hydropericardium hepatitis syndrome (HHS), which has resulted in huge economic losses to poultry industry recent years. Hence, a rapid and simple visual detection method needed for identification FAdV-4. In this study, three multienzyme isothermal amplification (MIRA) assays, basic MIRA, MIRA-qPCR MIRA-LFD were developed The primers reaction conditions optimized, specificity sensitivity assays evaluated. MIRA specific FAdV-4...