A5048203781- Bacterial biofilms and quorum sensing
- Salmonella and Campylobacter epidemiology
- Antimicrobial Resistance in Staphylococcus
- Aquaculture disease management and microbiota
- Moringa oleifera research and applications
- Clostridium difficile and Clostridium perfringens research
- Bacteriophages and microbial interactions
- Streptococcal Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- Microbial infections and disease research
- Infective Endocarditis Diagnosis and Management
- Oral microbiology and periodontitis research
- Plant Pathogenic Bacteria Studies
- Aquaculture Nutrition and Growth
- Fish Biology and Ecology Studies
- Animal Nutrition and Physiology
- Probiotics and Fermented Foods
- Medicinal Plants and Neuroprotection
- Viral gastroenteritis research and epidemiology
- Pharmacological Effects of Natural Compounds
- Nanoparticles: synthesis and applications
Zagazig University
2018-2025
University of Tennessee at Knoxville
2018-2025
Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen associated with severe morbidity and mortality poses significant threat to public health worldwide. The genetic diversity based on sequence types of MRSA strains was illustrated in previous studies; meanwhile, the along predominant type, especially Egypt, remains unknown. purpose current study determine clone ST239-MRSA (n = 50) isolated from different hosts clinical samples illustrate correlation between resistance...
Phytogenic feed additives have been gaining considerable interest due to their ability improve gut health and thereby performance of broiler chickens. The impact Glycyrrhiza glabra (licorice) extract (GE) on expression genes coding for tight junction proteins protection Campylobacter jejuni colonization in broilers has not discussed until now. Thus, the current study assessed effective dose GE maximum growth chickens, clear-cut molecular mechanisms related integrity intestine, controlling C....
The aim of the present study was to evaluate mannan oligosaccharides (MOS) or glycerol (GLY) as a carbon source on biofloc systems Nile tilapia (O. niloticus) juveniles. Fish (n = 750) were reared in open flow (Controls) (B-GLY and B-MOS) fed with plant fish protein over period twelve weeks. Total ammonia nitrogen nitrate decreased groups, while volume increased B-MOS. Compared controls, B-MOS B-GLY exhibited higher weight gain improved feed conversion, irrespectively diet. Serum level...
Surface-growing antibiotic-resistant pathogenic bacteria such as Escherichia coli and Staphylococcus aureus are emerging a global health challenge due to dilemmas in clinical treatment. Furthermore, their pathogenesis, including increasingly serious antimicrobial resistance biofilm formation, makes them challenging treat by conventional therapy. Therefore, the development of novel antivirulence strategies will undoubtedly provide path forward combatting these resistant bacterial infections....
Introduction Enterococcus faecalis , a common inhabitant of the feline gastrointestinal tract, has emerged as significant pathogen causing urinary tract infections (UTIs) in domestic cats. The rise multidrug-resistant E. strains and their propensity to form biofilms pose challenges treatment. This study investigated antibacterial antibiofilm activities hexagonal zinc oxide nanoparticles (ZnONPs) alone combination with streptomycin Moringa oleifera leaf extract (MOLe) against isolates from...
Shiga toxin-producing Escherichia coli (STEC) is causing outbreaks worldwide and a rapid detection method urgently needed. Loop-mediated isothermal amplification (LAMP) has attracted attention in the development of pathogen methods; however, current methods for LAMP amplicon suffer some drawbacks. In this study, we designed new by incorporating peroxidase-mimicking G-quadruplex DNAzyme simple colorimetric amplicon. As produces containing two molecules per unit, was termed Dual (cDDLAMP)....
Staphylococcus schleiferi and coagulans are opportunistic pathogens of animals humans. They were previously classified as subs . , respectively, recently reclassified separate species. S is frequently associated with dogs, whereas more commonly isolated from Coagulase activity status a defining characteristic the otherwise closely related However, use coagulase tests originally developed to distinguish aureus non-coagulase-producing staphylococci, for this purpose questionable basis their...
Campylobacter species are common commensals in the gastrointestinal tract of livestock animals; thus, animal-to-human transmission occurs frequently. We investigated for first time, class 1 integrons and associated gene cassettes among pan drug-resistant (PDR), extensively (XDR), multidrug-resistant (MDR) isolated from animals humans Egypt. were detected 58.11% analyzed chicken samples represented as 67.53% jejuni(C. jejuni) 32.47% coli (C. coli). C. jejuni isolates reported 51.42%, 74.28%,...
Coagulase activation of prothrombin by staphylococcus induces the formation fibrin deposition that facilitates establishment infection Staphylococcus species. activity is a key characteristic pseudintermedius; however, no coagulase gene or associated protein has been studied to characterize this activity. We report recombinant sharing 40% similarity aureus produced from putative S. pseudintermedius gene. Prothrombin was measured with chromogenic assay using thrombin tripeptide substrate....
Clostridium perfringens (C. perfringens) is an important pathogen in livestock animals and humans causing a wide array of systemic enteric diseases. The current study was performed to investigate the inhibitory activity myricetin (MYR), polyvinyl alcohol (PVA), zinc oxide (ZnO) nanocomposite against growth α-hemolysin C. isolated from beef meat chicken sources.The overall occurrence 29.8%. prevalence higher (38.3%) than products (10%). antimicrobial susceptibility testing revealed that...
The success of staphylococci as pathogens has been attributed, in part, to their ability evade hosts’ immune systems. Although the proteins involved evasion have extensively studied affecting humans little characterization done with Staphylococcus pseudintermedius, an important cause pyoderma dogs. aureus binder immunoglobulin (Sbi) interferes innate recognition by interacting multiple host proteins. In this study, a S. pseudintermedius gene that shares 38% similarity Sbi was cloned from...
Animal-to-human transmission is frequently linked to commensal bacteria in the gastrointestinal tract, as Campylobacter species. We provide a better insight into existence of cytolethal distending toxin (cdt) and flagellinA (flaA) genes different antimicrobial resistance patterns (pandrug-resistance (PDR), extensive drug-resistance (XDR) multidrug-resistance (MDR)] species recovered from chickens, milk, human sources Egypt. isolation rate was 89.44%, being 79.50% 20.50% for C. jejuni coli,...
Infectious coryza (IC), an acute respiratory disease of chickens, is caused by Avibacterium paragallinarum (A. paragallinarum). Herein, we evaluated the efficacy a polyvalent oil adjuvant IC vaccine against circulating A. field isolates recovered from chickens in Egypt. Thirty two were 165 chicken samples (19.39%) then identified phenotypic and polymerase chain reaction (PCR) assays. Serotyping hemagglutination inhibition (HI) test revealed identification both serotypes A C. The results...