A5101877007- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- COVID-19 Clinical Research Studies
- Infectious Encephalopathies and Encephalitis
- Respiratory viral infections research
- Anesthesia and Neurotoxicity Research
- Silymarin and Mushroom Poisoning
- Healthcare Technology and Patient Monitoring
- COVID-19 diagnosis using AI
- Selenium in Biological Systems
- Lipid metabolism and disorders
- Aerosol Filtration and Electrostatic Precipitation
- Thermal Regulation in Medicine
- Pediatric Pain Management Techniques
- Neonatal and Maternal Infections
- Infection Control and Ventilation
- Nosocomial Infections in ICU
- Whipple's Disease and Interleukins
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Fungal Infections and Studies
Children's Hospital of Chongqing Medical University
2014-2025
Chongqing Medical University
2014-2025
Peking University Third Hospital
2020
Peking University
2020
Shandong Agricultural University
2006-2009
There is a scarcity of data regarding coronavirus disease 2019 (COVID-19) infection in children from southeast and south Asia. This study aims to identify risk factors for severe COVID-19 among the region. an observational with hospitals contributing Pediatric Acute Critical Care Registry Laboratory-confirmed cases were included this registry. The primary outcome was severity as defined by World Health Organization (WHO) (mild, moderate, severe, or critical). Epidemiology, clinical...
The Pediatric Acute Lung Injury Consensus Conference developed a pediatric specific definition for acute respiratory distress syndrome (PARDS). In this definition, severity of lung disease is stratified into mild, moderate, and severe groups. We aim to describe the epidemiology patients with PARDS across Asia evaluate whether risk stratification accurately predicts outcome in PARDS.A multicenter, retrospective, descriptive cohort study.Ten multidisciplinary PICUs Asia.All mechanically...
Although multiple risk factors have been reported for adverse outcomes in children with severe pertussis, their predictive values and the benefits of interventions such as exchange transfusion remain poorly understood. Therefore, we aimed to comprehensively evaluate associated mortality pertussis assess potential therapy. A retrospective analysis 170 patients admitted Pediatric Intensive Care Unit (PICU) between January 2018 June 2024 was performed. Among patients, 38 (22.35%) died. The...
Objective: Hyperglycaemia is common amongst children with traumatic brain injury (TBI). We aim to investigate the association between early hyperglycaemia and poor clinical outcomes in moderate severe TBI.Methods: performed a retrospective study tertiary paediatric hospital May 2012 October 2014 of all patients TBI who were aged <16 years Glasgow Coma Scale (GCS) ≤13. The primary outcome was death. Secondary 14 ventilation-free, intensive care unit (PICU)-free 28 hospital-free days. defined...
Objectives: Extrapulmonary pediatric acute respiratory distress syndrome and pulmonary are poorly described in the literature. We aimed to describe compare epidemiology, risk factors for mortality, outcomes extrapulmonary syndrome. Design: This is a secondary analysis of multicenter, retrospective, cohort study. Data on ventilation, therapies, were collected analyzed. Patients classified into two mutually exclusive groups (extrapulmonary syndrome) based etiologies. Primary outcome was PICU...
Hand, foot, and mouth disease (HFMD) is an acute viral infection occurring mostly in infants children. Enterovirus 71 (EV71) occurs children < 5 years of age. Severe cases, however, are usually encountered under the age 3 years, exceedingly rare teenagers > 14 adults. We report a case HFMD 16-year-old male teenager residing Chonqing, China. The clinical presentation was typical included vesicular lesions oral mucosal ulcers, macular on palms soles. He developed severe neurological...
Abstract Background and purpose Pertussis is a serious infectious disease in young infants, severe cases frequently cause death. Our study explored risk factors for death from pertussis. Method A case-control of infants with pertussis admitted to the paediatric intensive care unit (PICU) Children’s Hospital Chongqing Medical University, China, January 1, 2013, June 30, 2019, was conducted. confirmed by clinical features laboratory examinations. Severe defined as patients resulting PICU...
To investigate the value of systemic inflammatory response syndrome (SIRS), pediatric sequential organ failure assessment (pSOFA) and critical illness score (PCIS) in predicting mortality sepsis intensive care units (PICU) from Southwest China.
To investigate respiratory virus infection in children with septic shock pediatric care units (PICU) China and its influence on clinical outcomes.
Introduction: Evidence supporting non-invasive ventilation (NIV) in paediatric acute respiratory distress syndrome (PARDS) remains sparse. We aimed to describe characteristics of patients with PARDS supported NIV and risk factors for failure. Materials Methods: This is a multicentre retrospective study. Only on were included. Data epidemiology clinical outcomes collected. Primary outcome was failure which defined as escalation invasive mechanical within the first 7 days PARDS. Patients...
基于对镇痛和镇静作用认识的深入以及新药不断推出，中华医学会儿科学分会急救学组等于2018年对"儿童重症监护治疗病房镇痛和镇静治疗专家共识（2013版）"进行了更新修订。2018版共识在镇痛和镇静的指征中增加了器官功能保护的内容；强调早期舒适镇痛、最小化镇静和人文关怀；更新和调整了儿童镇静的主观评估方法；增列了新的镇痛和镇静药物；并特别提出要重视儿童谵妄问题。.
There is wide variation in the overall clinical impact of novel coronavirus disease 2019 (COVID-19) across countries worldwide. Changes adopted pertaining to management pediatric patients, particular, provision respiratory support during COVID-19 pandemic poorly described Asia. We performed a multicenter survey 20 Asian hospitals determine workflow changes pandemic. Data from centers high-income (HIC), upper middle income (UMIC), and lower (LMIC) were compared. All sites over nine (HIC:...
Abstract Background Sepsis is a severe condition characterized by acute organ dysfunction resulting from an imbalanced host immune response to infections. Apolipoprotein H (APOH) critical plasma protein that plays crucial role in regulating various biological processes. However, the precise of APOH immunopathology paediatric sepsis remains unclear. Methods In this study, we evaluated concentration patients with and healthy individuals. experimental model caecal ligation puncture (CLP),...
镇痛镇静治疗是儿童重症监护病房患儿的基本治疗措施，而器官功能支持与保护是镇痛镇静治疗的核心目的。镇痛镇静治疗与血流动力学支持、机械通气、持续肾脏替代治疗等具有同样的临床地位，已成为脑保护、肺保护、休克治疗以及器官功能衰竭防治的重要手段。.
To investigate the clinical features, pathogen composition, and prognosis of septic shock in pediatric intensive care units (PICU) China.
<title>Abstract</title> Objective High white blood cell (WBC) counts has been identified as a risk factor for adverse outcomes in pertussis patients, but the predictive value of it and efficacy interventions such exchange transfusion remain poorly understood. Therefore, we endeavored to investigate impact on mortality severe children assess potential benefits therapy. Methods A retrospective analysis 170 patients admitted Pediatric Intensive Care Unit (PICU) between January 2018 June 2024...
Background and aims: Distribution drug resistance profile of pathogenic bacterium isolated from pediatric wound infections following the 2008 Wenchuan earthquake. Aims: May 12, 2008, earthquake occurred in Sichuan, China. Within 1 month after earthquake, 98 earthquakes injured children were admitted to Children's Hospital Chongqing Medical University hospital. Methods: According clinical manifestations, 50 cases diagnosed as infection. Wound secretions put into bacterial culture. Pathogens...
Intracranial hypertension is one of the most common critical diseases in children that associated with worse outcome including severe brain injury, cerebral hernia and leading cause mortality morbidity children.The management strategies are aimed at treating underlying diseases, controlling elevated intracranial pressure, maintaining adequate perfusion pressure preventing hernia.Medical decreasing widely used clinical practice should be caution. Key words: Intracranial...
Invasive fungal disease(IFD) in children can be life-threatening.Because of no differential clinical manifestations, the early treatment is difficult.In this paper, according to relevant literatures and practices recent years, we reviewed commonly used antifungal drugs choices invasive disease children. Key words: Invasive infections; Children; Treatment,
Most critically ill children have severe stress, the metabolic changes are specific and complex. Enternal nutrition early enternal can maintenance metabolism protect intestinal mucosal barrier digestive function. It also improve perfusion of tissue, regulate immune, significantly reduce infection incidence multiple organ dysfunction syndrome, occurrence infection, so as to prognosis. has broad prospects for clinical application. Early enteral is focus this paper, in order provide some...
As the preferred treatment for most patients with hemodynamic instability in intensive care unit(ICU), fluid resuscitation can be limited by cardiac function, that makes has no responsiveness and may cause risk of pulmonary edema increase.So, good is basic condition to make therapy successfully.For those patients, order lower correctly evaluate responsiveness, there are a large number studies direct at static dynamic pre-load parameters animals clinical patients.Those show how avoid...