A5088845365- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Vascular Procedures and Complications
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Central Venous Catheters and Hemodialysis
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Atherosclerosis and Cardiovascular Diseases
- Peripheral Artery Disease Management
- Cancer, Hypoxia, and Metabolism
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Adipokines, Inflammation, and Metabolic Diseases
- Cell Adhesion Molecules Research
- Coronary Artery Anomalies
- Cardiac Health and Mental Health
- Angiogenesis and VEGF in Cancer
- Lipoproteins and Cardiovascular Health
Kaohsiung Chang Gung Memorial Hospital
2016-2025
Chang Gung University
2016-2025
Sin-Lau Christian Hospital
2020-2022
Yavapai College
2015
Taoyuan Chang Gung Memorial Hospital
2010
Istituto Nazionale di Fisica Nucleare, Sezione di Milano
2010
Deleted Institution
2010
Brigham and Women's Hospital
2009
Chang Gung Memorial Hospital
2003-2007
Memorial Hospital of South Bend
2003-2006
Abstract Background Heart failure (HF) continues to be the major cause of hospitalizations. Despite numerous significant therapeutic progress, mortality rate HF is still high. This longitudianl cohort study aimed investigate associations between hematologic inflammatory indices neutrophil percentage-to-albumin ratio (NPAR), neutrophil-to-lymphocyte (NLR), platelet-to-lymphocyte (PLR), and all-cause in community-dwelling adults with HF. Methods Adults aged 20 older US National Health...
Abstract Background The non‐vitamin K oral anticoagulant (NOAC), edoxaban, is approved for stroke prevention in patients with atrial fibrillation (AF) many Asian countries. Nonetheless, data on its long‐term effectiveness and safety routine clinical practice are limited Taiwan. Methods Global ETNA‐AF (Edoxaban Treatment routiNe prActice) registry an observational study that integrates of AF receiving edoxaban from multiple regional registries. Here, we report the subgroup analysis two‐year...
Background: Although recent studies suggest that percutaneous coronary intervention (PCI) with drug-eluting stents (DES) achieves clinical outcomes comparable to artery bypass graft surgery (CABG) for unprotected left main (ULMCA) disease, long-term are rarely performed. Methods and Results: This study reviewed in 363 patients undergoing CABG (n=216), PCI DES (n=94) or bare-metal stent (BMS) (n=53) ULMCA stenosis between January 2000 March 2007. The group had more diabetes (50.5%) 3-...
Few studies have reported results for transradial (TR) percutaneous coronary intervention (PCI) chronic total occlusion (CTO) lesions. The purpose of this study was to evaluate the feasibility and safety bilateral radial PCI CTO lesions.Eighty-five consecutive patients with lesions received via a TR approach. A high artery puncture (10-15 cm above styloid process) accommodating 7 Fr catheter (85 long) used retrograde approach, 6 in other an antegrade Retrograde wiring conducted primarily or...
Contrast-induced nephropathy (CIN) is a leading cause of morbidity and mortality in patients undergoing percutaneous coronary intervention (PCI). Limited data, however, are available on predictors CIN PCI for chronic total occlusion (CTO) lesions. The aim the study was to determine risk developing CTO by studying effects clinical variables, interventional techniques, lesion characteristics renal function.This retrospective analysis included consecutive referred between January 2002 December...
Cardiac amyloidosis is one form of systemic caused by abnormal amyloid fibrils deposited in the extracellular space myocardium causing heart failure because restrictive cardiomyopathy and conduction disturbances. The incidence prevalence cardiac are higher than previously noted, particularly among special populations. most common forms light chain transthyretin cardiomyopathy. Even though more 70% patients with have amyloidosis, diagnosis often delayed, suggesting significant gaps knowledge...
Atherosclerotic cardiovascular disease (ASCVD) is one of the leading causes death worldwide and in Taiwan. It highly prevalent has a tremendous impact on global health. Therefore, Taiwan Society Cardiology developed these best-evidence preventive guidelines for decision-making clinical practice involving aspects primordial prevention including national policies, promotion health education, primary risk factors, management control factors. These cover full spectrum ASCVD, chronic coronary...
Hyperglycaemia causes endothelial dysfunction, which is the initial process in development of diabetic vascular complications. Upon injury, cells undergo an endothelial-to-mesenchymal transition (EndMT), lose their specific marker, and gain mesenchymal phenotypes. This study investigated effect liraglutide, a glucagon-like peptide 1 (GLP-1) receptor agonist, on EndMT inhibition neointima formation mice induced by streptozotocin. The with wire-induced injury right carotid artery were treated...
The study population consisted of 234 consecutive patients hospitalized for acute exacerbation congestive heart failure secondary to non-ischemic cardiomyopathy. Of the patients, there were 55 in-hospital deaths. Their medical records deliberatively reviewed and association 38 clinical, hemodynamic biochemical variables with mortality was evaluated by multiple stepwise logistic regression analysis. following statistically associated mortality: profound cardiogenic shock, severe hyponatremia,...
Abstract Although sporadic successful cases using the transradial approach (TRA) for carotid stenting have been reported, safety and feasibility of either TRA or a transbrachial (TBA) not fully investigated. Recently, we developed safe feasible method cerebrovascular angiographic studies. This study investigated whether TBA 7‐French (F) Kimny guiding catheter is patients with severe stenosis. Thirteen were enrolled into this (age range, 63–78 years). Seven these 13 had peripheral vascular...
Percutaneous coronary intervention (PCI) is considered an excellent alternative treatment for unprotected left main artery (ULMCA) stenoses. Most PCIs ULMCA stenoses are performed via the transfemoral approach. The feasibility and safety of transradial approach this particular entity unknown. present study assessed feasibility, 1-year outcomes stenting stenoses.Of 131 consecutive patients who underwent stenoses, 113 (86.3%) received using All procedures were with 6 or 7 French (Fr) catheters...
The prognostic value of interleukin (IL)-18 in patients with ST-segment elevation acute myocardial infarction (STEMI) is currently unclear. Thus, the purpose this study was to test whether circulating IL-18 level can predict prognosis STEMI undergoing primary percutaneous coronary intervention (PCI).A prospective cohort conducted 267 consecutive onset <12 h who were PCI. Blood samples for plasma collected catheterization laboratory following vascular puncture. also evaluated 25 healthy and...
There is no data about the utilisation of a single guiding catheter for current routine, transradial, right and left coronary diagnosis intervention. We investigated feasibility safety using 6Fr, Ikari (IL) 3.5 this purpose.This prospective single-centre study enrolled 621 consecutive patients referred transradial angiography with ad hoc The radial artery was successfully accessed in 96.8% patients. Right coronaries were engaged 98.1% cases. Engagement good back-up at (device success)...
ABSTRACT Elevation of free fatty acids (FFAs) is known to affect microvascular function and contribute obesity‐associated insulin resistance, hypertension, microangiopathy. Proliferative synthetic vascular smooth muscle cells (VSMCs) increase intimal thickness destabilize atheromatous plaques. This study aimed investigate whether saturated palmitic acid (PA) monounsaturated oleic (OA) modulate autophagy activity, cell proliferation, tissue remodeling in an aortic VSMC line. Exposure PA OA...
Background. The study aimed to verify the effect of primary percutaneous coronary intervention (PPCI) with <60 min door-to-balloon time on ST segment elevation myocardial infarction (STEMI) patients’ prognoses. Methods. Outcomes patients receiving PPCI were compared those 60–90 min. Result. Totally, 241 STEMI (191 Killip classes I or II) and 104 (71 received min, respectively. II had better thrombolysis in (TIMI) flow (9.2% fewer TIMI <3, <mml:math...
For the primary prevention of atherosclerotic cardiovascular disease (ASCVD), recommended treatment target for each modifiable risk factor is as follows: reducing body weight by 5-10%; blood pressure < 130/80 mmHg (systolic 120 in high-risk individuals); low-density lipoprotein cholesterol (LDL-C) 100 mg/dL individuals, LDL-C 115 moderate-risk 130 low-risk and 160 those with a minimal; complete persistent abstinence from cigarette smoking; hemoglobin A1C 7.0%; fulfilling amounts six food...