- Acupuncture Treatment Research Studies
- Functional Brain Connectivity Studies
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Transcranial Magnetic Stimulation Studies
- Spondyloarthritis Studies and Treatments
- EEG and Brain-Computer Interfaces
- Bone and Joint Diseases
- Ophthalmology and Eye Disorders
- Biofield Effects and Biophysics
- Neuroscience and Music Perception
- Mental Health Research Topics
- Neuroscience and Neuropharmacology Research
- Heart Rate Variability and Autonomic Control
- Traditional Chinese Medicine Studies
- Neural dynamics and brain function
- Glaucoma and retinal disorders
- Neural and Behavioral Psychology Studies
- Psychosomatic Disorders and Their Treatments
- Schizophrenia research and treatment
- Ocular Surface and Contact Lens
- Neurological Disorders and Treatments
- Autoimmune and Inflammatory Disorders Research
- Complementary and Alternative Medicine Studies
- Vestibular and auditory disorders
Sichuan University
2010-2025
Zhongshan Hospital of Xiamen University
2025
West China Hospital of Sichuan University
2008-2024
Lyell Immunopharma (United States)
2023-2024
Fudan University Shanghai Cancer Center
2023
Southern Medical University
2014-2021
Nanfang Hospital
2017-2021
Guangdong Provincial People's Hospital
2019-2021
Creative Commons
2017
BT Research
2017
Autophagy is confirmed to be involved in the onset and development of depression, some antidepressants took effect by influencing autophagic process. Electroacupuncture (EA), as a common complementary treatment for may share mechanism autophagy hippocampus like antidepressants. To investigate that, sixty Sprague-Dawley rats firstly went through chronic unpredictable mild stress (CUMS) model establishment, 15 were assigned control group. After modeling, 45 successfully CUMS-induced randomly...
Studies have shown that basic fibroblast growth factor (FGF2) is a neurotrophic associated with depression. Electroacupuncture (EA) has been to be an effective treatment for In the current study, we observed effects of EA on hippocampal FGF2 and astrocytes, further investigated mechanism underlying antidepressant effect EA. The chronic unpredictable mild stress (CUMS) method were selected induce depressive-like behaviors rats. Paroxetine commonly used was as positive control drug in this...
This study aimed to assess the role of fibrinogen (Fib) albumin (ALB) ratio (FAR) in ankylosing spondylitis (AS) and its association with disease activity.135 AS patients 76 age - gender matched healthy controls were collected this retrospective study. Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) score was used divide into remission group (BASDAI < 4) active ≥ 4). The between FAR BASDAI evaluated by Spearman correlation. Receiver operating characteristic (ROC) curve made...
To explore the effect of acupuncture at HT7 on heart rate variability (HRV) in healthy volunteers.120 subjects were divided into four groups using a random number table. The following interventions used: verum acupuncture; non-penetrating sham point; and no acupuncture. HRV was recorded 10 min before, during after each stimulation an Actiheart ECG recorder.The group had higher very-low frequency, low frequency high components compared with control but not also SD normal intervals needling...
Acupuncture is increasingly used in the treatment for Parkinson's disease (PD). This multi-center randomized controlled trial investigated use of acupuncture conjunction with western medication Madopar (levodopa and benserazide) to evaluate effect integrated therapy on improving motor non-motor symptoms PD patients. Seventy-six patients from three hospitals were randomly assigned a group (acupuncture + Madopar, n = 38) or control (Madopar, participated 12-week (2 four-week courses...
To investigate the clinical effects of electroacupuncture (EA) on head points for improving gnosia in patients with vascular dementia (VD). 90 VD were randomly divided into a drug group, an EA group and plus group. Scoring MMSE scale detecting relevant potentials done before treatment after 6-week treatment. Gnosia was improved all three groups no significant difference by intergroup comparison. The above therapies can improve gnosia, reduce psychological stress, strengthen attention shorten...
Objectives To investigate the antidepressant effects of electroacupuncture (EA) on chronic unpredictable mild stress (CUMS) in rats, as well EA hippocampal neurons, synaptic morphology, and 5-hydroxytryptamine (HT) receptor expression. Methods Forty adult male Wistar rats were randomly divided into normal control, CUMS, EA, paroxetine groups. CUMS modeling was performed for 21 days, followed by 14 days intervention: group underwent stimulation GV20 GV29 acupuncture points 30 minutes daily;...
The C-reactive protein (CRP) to albumin (ALB) ratio (CAR) has emerged as a novel inflammatory biomarker. This study was designed investigate the role of CAR in disease activity axial spondyloarthritis (axSpA). A total 241 patients and 61 healthy controls were retrospectively enrolled this study. AxSpA further divided into inactive group (n = 176) active 65) according Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) cutoff value 4. Laboratory data clinical assessment indices...
The acute effect of acupuncture on Alzheimer's disease, i.e., brain activation during treatment, has been reported. However, the long-term in disease is unclear. Therefore, this study, we performed needling at Zusanli (ST36) or a sham point (1.5 mm lateral to ST36) rat model, for 30 minutes, once per day, days. rats underwent 18F-fluorodeoxyglucose positron emission tomography scanning. Positron images were processed with SPM2. areas activated after ST36 included left hippocampus, orbital...
The present study aims to detect the specific and common impairment index relative evoked brain potentials (EBPS ) in deficit schizophrenia (DS) nondeficit (NDS), investigates relationship between EBPs clinical variables.The used 21 patients with DS, 38 NDS, 50 healthy controls (HCs) investigate P300 waves, mismatch negative (MMN), sensory gating (SG) P50 contingent variation (CNV). A comparison of three groups variables were performed using general linear model analyses partial correlation,...
A noninferiority trial was conducted to evaluate the efficacy of a single evening dose fixed-combination latanoprost 50 μg/mL and timolol 0.5 mg/mL (Xalacom®; LTFC), in Chinese patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH) who were insufficiently controlled on β-blocker monotherapy β-blocker-based dual therapy.This 8-week, randomized, open-label, parallel-group, study compared once-daily dosing LTFC unfixed combination latanoprost, one drop evening, timolol,...
Background: Schizophrenia is a highly heterogeneous disease. Event-related potentials have been regarded to establish intermediate phenotypes of schizophrenia. Our previous study found that patients with deficit schizophrenia (DS) are relatively homogeneous and show significantly longer onset latency contingent negative variation (CNV) expectancy wave. Aims: To further examine CNV in first-episode drug-naïve DS or bipolar I disorder (BP I) psychotic features, also investigate correlations...
To observe the therapeutic effects of electro-acupuncture (EA) combined with psychological intervention on symptom somzatization or obsession and mental depression anxiety P50 Auditory Evoked Potential (AEP) internet addiction disorder (IAD). One hundred twenty cases IAD were randomly divided into an EA group, a psycho-intervention (PI) group comprehensive therapy (EA plus PI) group. Patients in treated EA. PI cognition behavior therapy. intervention. Scores IAD, scores checklist 90...
The study attempted to explore that the synergistic effect of acupoints combination is not a simple superposition single acupoint's by comparing and analyzing changes blood pressure (BP), SF-36, brain regions after acupuncture treatment. 47 patients were randomly divided into LR3+KI3 group, LR3 KI3 group. Subjects received Rs-fMRI scan, BP measurement, SF-36 questionnaires before treatment short-term After treatment, there no significant differences in among 3 groups, compared case SBP...