A5012045841- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Quantum Chromodynamics and Particle Interactions
- Radiation Detection and Scintillator Technologies
- Particle Detector Development and Performance
- Medical Imaging Techniques and Applications
- Atomic and Subatomic Physics Research
- Dark Matter and Cosmic Phenomena
- Computational Physics and Python Applications
- Nuclear Physics and Applications
- Luminescence Properties of Advanced Materials
- Cosmology and Gravitation Theories
- Neutrino Physics Research
- Advanced Semiconductor Detectors and Materials
- Advanced X-ray and CT Imaging
- Photonic and Optical Devices
- Photonic Crystals and Applications
- Radiation Therapy and Dosimetry
- Radioactivity and Radon Measurements
- Black Holes and Theoretical Physics
- Astrophysics and Cosmic Phenomena
- Optical Coatings and Gratings
- Particle Accelerators and Free-Electron Lasers
- Terahertz technology and applications
- Perovskite Materials and Applications
European Organization for Nuclear Research
2016-2025
Instituto de Instrumentación para Imagen Molecular
2020-2024
University of Antwerp
2024
A. Alikhanyan National Laboratory
2022-2024
Institute of High Energy Physics
2021-2024
Universitat Politècnica de València
2020-2024
Huazhong University of Science and Technology
2023
National Nuclear Energy Commission
2023
Imperial College London
2021
University of Milano-Bicocca
2018-2019
For a long time the discovery of new scintillators has been more serendipitous than driven by deep understanding mechanisms at origin scintillation process. This situation dramatically changed since 1990's with an increased demand for better performance large particle physics experiments as well medical imaging. It is now possible to design scintillator specific purpose. The bandgap can be adjusted, traps energy levels and their concentration finely tuned influence damped or on contrary...
This paper presents new developments in inorganic scintillators widely used for radiation detection. It addresses major emerging research topics outlining current needs applications and material sciences issues with the overall aim to provide an up-to-date picture of field. While traditional forms have been crystals ceramics, on films, nanoparticles, microstructured materials is discussed as these can bring functionality therefore find The last part contribution reports very recent...
There is an increasing demand for high sensitivity multiparametric medical imaging approaches. High precision time-of-flight positron emission tomography (TOFPET) scanners have a very potential in this context, providing improvement the signal-to-noise ratio of reconstructed image and possibility to further increase already (at pico-molar level) PET scanners. If present state-of-the art coincidence time resolution about 500 ps can be improved, it will open way particular significant...
Solid state photodetectors like silicon photomultipliers (SiPMs) are playing an important role in several fields of medical imaging, life sciences and high energy physics. They able to sense optical photons with a single photon detection time precision below 100 ps, making them ideal candidates read the generated by fast scintillators flight positron emission tomography (TOF-PET). By implementing novel high-frequency readout electronics, it is possible perform completely new evaluation best...
Since the seventies, positron emission tomography (PET) has become an invaluable medical molecular imaging modality with unprecedented sensitivity at picomolar level, especially for cancer diagnosis and monitoring of its response to therapy.More recently, combination X-ray computed (CT) or magnetic resonance (MR) added high precision anatomic information in fused PET/CT PET/MR images, thus compensating modest intrinsic spatial resolution PET.Nevertheless, a number challenges call further...
Scintillator based radiation detectors readout by SiPMs successively break records in their reached time resolution. Nevertheless, new challenges of flight positron emission tomography (TOF-PET) and high energy physics are setting unmatched goals the 10 ps range. Recently it was shown that frequency (HF) significantly improves measured single photon resolution (SPTR), allowing to evaluate intrinsic performance large area devices; e.g. FBK NUV-HD mm2 40 m avalanche diode (SPAD) size achieve...
The coincidence time resolution (CTR) of scintillator based detectors commonly used in positron emission tomography is well known to be dependent on the scintillation decay () and number photons detected (), i.e. . However, it still an open question what extent rise other fast or prompt photons, e.g. Cherenkov at beginning process influence CTR. This paper presents measurements rate for different LSO type crystals, LSO:Ce, LYSO:Ce, LSO:Ce codoped Ca LGSO:Ce. For various LSO-type samples...
Time of flight (TOF) in positron emission tomography (PET) has experienced a revival interest after its first introduction the eighties. This is due to significant progress solid state photodetectors (SiPMs) and newly developed scintillators (LSO derivatives). Latest developments at Fondazione Bruno Kessler (FBK) lead NUV-HD SiPM with very high photon detection efficiency around 55%. Despite large area 4×4 mm2 it achieves good single time resolution (SPTR) 180±5ps FWHM. Coincidence (CTR)...
The coincidence time resolution (CTR) becomes a key parameter of 511keV gamma detection in flight positron emission tomography (TOF-PET). This is because additional information obtained through timing leads to better noise suppression and therefore signal ratio the reconstructed image. In this paper we present results CTR measurements on two different SiPM technologies from FBK coupled LSO:Ce codoped 0.4%Ca crystals. We compare performed at separate test setups, i.e. CERN FBK, showing that...
Scintillation crystals have a wide range of applications in detectors for high energy and medical physics. They are recquired to not only good resolution, but also excellent time resolution. In applications, L(Y)SO commonly used flight positron emission tomography (TOF-PET). This study aims at determining the experimental theoretical limits timing using based scintillators coupled silicon photomultipliers (SiPMs). Measurements on time-over-threshold method coincidence setup utilizing...
A key step to improve the coincidence time resolution of positron emission tomography detectors that exploit small populations promptly emitted photons is improving single photon (SPTR) silicon photomultipliers (SiPMs). The influence electronic noise has previously been identified as dominant factor affecting SPTR for large area, analog SiPMs. In this work, we measure achievable with front end readout minimizes noise. With circuit, measured one FBK NUV avalanche photodiode (SPAD) was also...
Comparison of the timing performance different silicon photomultipliers (SiPMs) can be useful for applications that employ these devices. In our study, we characterize some currently available SiPMs to compare single photon time resolution (SPTR) values measured using a 420 nm laser with pulse width 42 ps FWHM. SPTR in range 175–330 FWHM were most 3 × mm2 and 4 devices varied producer type SiPM. Factors influencing including area, cell non-uniformity SPAD (single avalanche diode) jitter...
Bismuth germanate (BGO) shows good properties for positron emission tomography (PET) applications, but was substituted by the development of faster crystals like lutetium oxyorthosilicate (LSO) time-of-flight PET (TOF-PET). Recent improvements in silicon photomultipliers (SiPMs) and fast readout electronics make it possible to access Cherenkov photon signal produced upon 511 keV interaction, which makes BGO a cost-effective candidate TOF-PET. Tails time-delay distribution, however, remain...
The emergence of new solid-state avalanche photodetectors, e.g. SiPMs, with unprecedented timing capabilities opens ways to profit from ultrafast and prompt photon emission in scintillators. In time flight positron tomography (TOF-PET) high energy detectors based on scintillators the ultimate coincidence resolution (CTR) achievable is proportional square root scintillation rise time, decay reciprocal light yield, CTR∝τrτd∕LY. Hence, precise study very first tens picoseconds indispensable...
Abstract The technological challenge imposed by the time resolution essential to achieve real-time molecular imaging calls for a new generation of ultrafast detectors. In this contribution, we demonstrate that CdSe-based semiconductor nanoplatelets can be combined with standard scintillator technology 80 ps coincidence on hybrid functional pixel. This result contrasts fact overall detector light output is considerably affected loss index-light-guiding. Here, exploit principle 511 keV energy...
Achieving fast timing in positron emission tomography (PET) at the level of few tens picoseconds is limited by photon rate existent materials with standard scintillation mechanisms. This has led to consider quantum confined excitonic sub-1 ns semiconductors as a viable solution enhance amount fast-emitted photons produced per gamma event. However introduction nanocrystals and nanostructures into domain radiation detectors challenging problem. In order move forward along this line, bulk...
We report on the progress a first generation of realistic size metascintillators for time-of-flight PET. These heterostructures combine dense LYSO or BGO plates, interleaved with fast scintillator layers producing bunch prompt photons from energy leakage recoil photoelectric electron. From Geant4 simulation sharing distribution between and 42 LYSO-based BGO-based configurations, detailed study timing performance has been performed selection most promising 12 14 metascintillators. A Monte...
Scintillators are important materials for radiographic imaging and tomography (RadIT), when ionizing radiations used to reveal internal structures of materials. Since its invention by R\"ontgen, RadIT now come in many modalities such as absorption-based X-ray radiography, phase contrast imaging, coherent diffractive high-energy X- $\gamma-$ray radiography at above 1 MeV, computed (CT), proton (IT), neutron IT, positron emission (PET), electron muon tomography, etc. Spatial, temporal...