A5071561023- Surgical site infection prevention
- Traumatic Ocular and Foreign Body Injuries
- Surgical Sutures and Adhesives
- Tuberculosis Research and Epidemiology
- Venomous Animal Envenomation and Studies
- Global Maternal and Child Health
- Fiscal Policy and Economic Growth
- Leech Biology and Applications
- Trauma and Emergency Care Studies
- Infection Control in Healthcare
- Disaster Response and Management
- Ethics in medical practice
- Climate Change and Health Impacts
- Regional Economics and Spatial Analysis
- Global Health and Surgery
- Biotechnology and Related Fields
- Pharmaceutical Economics and Policy
- Telemedicine and Telehealth Implementation
- Ethics in Clinical Research
- Delphi Technique in Research
- Antenna Design and Analysis
- Full-Duplex Wireless Communications
- Migration, Health and Trauma
- Inhalation and Respiratory Drug Delivery
- E-Government and Public Services
Médecins Sans Frontières
2014-2022
Médecins Sans Frontières
2012-2018
Wake Forest University
2008-2010
University of Pennsylvania
1996-2006
University City Science Center
2001
BackgroundAround 500 000 people worldwide develop rifampicin-resistant tuberculosis each year. The proportion of successful treatment outcomes remains low and new treatments are needed. Following an interim analysis, we report the final safety efficacy TB-PRACTECAL trial, evaluating oral regimens for tuberculosis.MethodsThis open-label, randomised, controlled, multi-arm, multicentre, non-inferiority trial was conducted at seven hospital community sites in Uzbekistan, Belarus, South Africa,...
Armed conflicts are a major contributor to injury and death globally. Conflict-related injuries associated with high risk of wound infection, but it is unknown what extent infection directly relates sustainment life restoration function. The aim this study was investigate the outcome resource consumption among civilians receiving acute surgical treatment due conflict-related injuries. Patients without infections were compared. We performed cohort using routinely collected data from 457...
Humanitarian organisations often work alongside those responsible for serious wrongdoing. In these circumstances, accusations of moral complicity are sometimes levelled at decision makers. These can carry a strong if unfocused charge and frequently the source significant unease. this paper, we explore meaning usefulness its relation to accountability. We also examine impact concerns about on motivation humanitarian staff risk that may lead retreat into narcissism. Moral narcissism is...
Abstract Background Malaria epidemics in highland areas of Kenya cause significant morbidity and mortality. Methods To assess treatment-seeking behaviour for malaria these areas, a questionnaire was administered to 117 randomly selected households the area Kipsamoite, Kenya. Self-reported episodes occurred 100 adults 66 children. Results The most frequent initial sources treatment children were medical facilities (66.0% 66.7%) local shops (19.0% 30.3%). Adults who initially visited facility...
Fluid therapy in severely malnourished children is hypothesized to be deleterious owing compromised cardiac function. We evaluated World Health Organization (WHO) fluid resuscitation guidelines for hypovolaemic shock using myocardial and haemodynamic function safety endpoints. A prospective observational study of two sequential management strategies was conducted at East African hospitals. Eligible participants were children, aged 6–60 months, with secondary gastroenteritis. Group 1 received...
In armed conflict, injuries among civilians are usually complex and commonly affect the extremities. Negative pressure wound therapy (NPWT) is an alternative to standard treatment of acute conflict-related extremity wounds. We aimed compare safety effectiveness NPWT with that treatment.In this pragmatic, randomised, controlled superiority trial done at two civilian hospitals in Jordan Iraq, we recruited patients aged 18 years or older, presenting a within 72 h after injury. Participants were...
This article explores the implications of moving public participation GIS (PPGIS) onto World Wide Web. It discusses potential benefits and impediments using Web for PPGIS application; it then uses a project developed solely on as case study to illustrate various issues such projects may face. finds that cost-benefit calculus in this transition is ambivalent: whereas some costs decrease, other threshold actually increase. Moving will not undermine traditional intermediation role but, rather,...
Prospective surveillance is a recognised approach for measuring death rates in humanitarian emergencies. However, there limited evidence on how such should optimally be implemented and data are actually used by agencies. This case study investigates the implementation utilisation of mortality Médecins Sans Frontières (MSF) eastern Chad. We aimed to describe analyse community-based system, trends these guide MSF's operational response. The included 5 MSF sites including 2 refugee camps 3...
In 2009, Médecins Sans Frontières (MSF) started a pilot trial of store-and-forward telemedicine to support field workers. One network was operated in French and one English; third, Spanish brought into operation 2012. The three pilots were then combined form single multilingual tele-expertise system, tailored MSF staff. We conducted retrospective analysis all cases referred from April 2010 March 2014. also carried out survey users December 2013. A total 1039 referrals received 41 countries,...
Hand hygiene adherence monitoring and feedback can reduce health care-acquired infections in hospitals. Few low-cost hand tools exist low-resource settings.To pilot an open-source application for mobile devices interactive analytical dashboard the collection visualization of care workers' data.This prospective multicenter quality improvement study evaluated preintervention postintervention with 5 Moments Hygiene, as suggested by World Health Organization, among workers from April 23 to May...
Kiran Jobanputra and colleagues describe an ethics framework to support the oversight of innovation projects in medical humanitarian contexts.
Clinical outcomes after negative-pressure wound therapy (NPWT) and standard treatment of conflict-related extremity wounds are similar. In resource-limited settings, cost affects the choice treatment. We aimed to estimate treatment-related costs NPWT in comparison with for wounds.We derived outcome data from a randomized, controlled superiority trial that enrolled adult (≥ 18 years) patients acute (≤ 72 h) at two civilian hospitals Jordan Iraq. Primary endpoint was mean healthcare (adjusted...
Globally, armed conflict is a major contributor to mortality and morbidity. The treatment of war-associated injuries largely experience-based. Evidence weak due difficulty in conducting medical research war settings. A qualitative method could provide insight into the specific challenges associated with providing health care injured civilians. aim this study was explore hospital-based physicians encounter wound management, focusing on surgical intervention antibiotic use. Semi-structured,...
Healthcare-associated infections (HAIs) constitute a major contributor to morbidity and mortality worldwide, with greater burden on low- middle-income countries. War-related injuries generally lead large tissue defects, high risk of infection. The aim this study was explore how physicians in country an emergency setting perceive HAI antibiotic resistance (ABR). Ten at Jordanian hospital supported by Médecins Sans Frontières were interviewed face-to-face. recorded interviews transcribed...
Brown recluse spider ( Loxosceles ) bites cause lesions ranging from chronic necrotic ulcers to acute life‐threatening sepsis. Based on our experience in treating and wounds with negative pressure, we postulated that vacuum‐assisted closure (VAC) would be valuable this application. Chester pigs were procured injected purified brown venom, 1 µl of venom two anterior sites 0·1 posterior their dorsum. For each concentration treatment consisted either VAC or dry, non adherent dressings (control...
Abstract A point-prevalence survey of mothers and neonates admitted to an obstetrics emergency hospital in Port-au-Prince, Haiti, revealed that 13 127 gram-negative bacteria isolates (10%) from rectal swabs were ESBL-positive women 30 59 (51%) neonates. Length stay antibiotic consumption risk factors for ESBL colonization.
Abstract Background The UK government committed to undertaking impact assessments of its policies on the health populations in low and middle-income countries cross-government strategy “Health is Global”. To facilitate this process, Department Health, collaboration with National Heart Forum, initiated a project pilot use global assessment guidance framework toolkit for policy-makers. This paper aims stimulate debate about desirability feasibility by describing drawing lessons from first...
Brown recluse spider (Loxosceles sp) bites continue to be a significant challenge manage clinically. Sequelae from these lesions range chronic necrotic ulcers that persist for months an acute life-threatening course of sepsis. Negative pressure wound therapy using vacuum-assisted closure (VAC) has been described use in both and wounds. We present novel application the this retrospective review eight clinical cases treated with VAC.
Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous malignancy. Intraoperative imprint cytology (IIC) can potentially avoid second operations for completion lymphadenectomy when nodal metastases are found during staging with sentinel lymph node biopsy (SLN). This represents the first series of IIC MCC we aware and our initial experience. Patients biopsy-proven underwent SLN (at time wide excision) using double indicator technique 99technetium sulfur colloid isosulfan blue. were...
In armed conflict, injuries commonly affect the extremities and contamination with foreign material often increases risk of infection. The use negative-pressure wound therapy has been described in treatment acute conflict-related wounds, but reports are retrospective limited follow-up.The objective this study is to investigate effectiveness safety patients extremity wounds.This a multisite, superiority, pragmatic randomized controlled trial. We considering for inclusion 18 years age older...