A5101392287- Atrial Fibrillation Management and Outcomes
- Cardiac tumors and thrombi
- Optimal Power Flow Distribution
- Dementia and Cognitive Impairment Research
- Advanced Surface Polishing Techniques
- Metallurgical Processes and Thermodynamics
- Metabolism, Diabetes, and Cancer
- Power System Reliability and Maintenance
- Lymphoma Diagnosis and Treatment
- Cerebral Palsy and Movement Disorders
- Pancreatic and Hepatic Oncology Research
- Natural product bioactivities and synthesis
- Inhalation and Respiratory Drug Delivery
- Integrated Energy Systems Optimization
- Electric Power System Optimization
- Minerals Flotation and Separation Techniques
- Bacteriophages and microbial interactions
- CNS Lymphoma Diagnosis and Treatment
- Sirtuins and Resveratrol in Medicine
- Pancreatic function and diabetes
- Tissue Engineering and Regenerative Medicine
- Bioactive Compounds and Antitumor Agents
- Blood Pressure and Hypertension Studies
- Vascular Tumors and Angiosarcomas
- Reproductive System and Pregnancy
Tianjin Medical University General Hospital
2025
Affiliated Hospital of Hebei University
2025
Nankai University
2024-2025
Kunming University of Science and Technology
2025
Ministry of Education of the People's Republic of China
2024
Harbin Medical University
2024
Second Affiliated Hospital of Harbin Medical University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Beijing Institute of Technology
2024
Jiangxi Academy of Sciences
2024
Abstract Self‐assembly in living cells represents one versatile strategy for drug delivery; however, it suffers from the limited precision and efficiency. Inspired by viral traits, we here report a cascade targeting‐hydrolysis‐transformation (THT) assembly of glycosylated peptides holistically resembling infection efficient cargo delivery combined tumor therapy. We design peptide via incorporating β‐galactose‐serine residue into bola‐amphiphilic sequences. Co‐assembling with two counterparts...
ConspectusEmulating the structural features or functions of natural systems has been demonstrated as a state-of-the-art strategy to create artificial functional materials. Inspired by assembly and bioactivity proteins, self-assembly peptides into nanostructures represents promising approach for creating biomaterials. Conventional assembled peptide biomaterials are typically formulated in solution delivered pathological sites implementing theranostic objectives. However, this translocation...
Despite significant progress achieved in artificial self-sorting solution, operating the body remains a considerable challenge. Here, we report an vivo peptide system via situ assembly evolution for combined cancer therapy. The
Abstract Aberrant signaling in tumor cells induces nonmetabolic functions of some metabolic enzymes many cellular activities. As a key glycolytic enzyme, the function hexokinase 2 (HK2) plays role immune evasion. However, whether HK2, dependent its activity, human pancreatic ductal adenocarcinoma (PDAC) tumorigenesis remains unclear. Here, we demonstrated that HK2 acts as protein kinase and phosphorylates IκBα at T291 PDAC cells, activating NF‐κB, which enters nucleus promotes expression...
Abstract Background Left ventricular thrombus (LVT) is a serious complication after myocardial infarction. However, due to its asymptomatic nature, early detection challenging. We aimed explore the differences in clinical correlates of LVT found acute subacute and chronic phases Methods collected data from 153 patients who were diagnosed with infarction at Affiliated Hospital Qingdao University January 2013 December 2022. Baseline information, inflammatory markers, transthoracic...
Primary vitreoretinal lymphoma (PVRL) is often associated with central nervous system involvement, contributing to a heightened mortality rate, thus imaging features that are characteristic enough be potential biomarkers of PVRL important, either in diagnosis or assessment disease activity. This report details the case 68-year-old male who presented blurred vision both eyes persisting for 2 months. Fundus examination demonstrated vitreous opacity and multiple subretinal yellow nodular...
Sapphire crystals are extensively used in laser high-energy weapon systems due to their exceptional optical properties. However, achieving high surface quality and minimal damage sapphire is extremely challenging. This paper presents a novel method, force magnetic shear combined with chemical rheological polishing (FMS-CRP), designed enhance the of sapphire. A model pressure (Pd) FMS-CRP zone was developed based on Reynolds magnetisation equation. The material removal rate (MRR) derived from...
Abstract With the increasingly severe environmental pollution problem, Integrated Energy System (IES) with power system as core can promote consumption of renewable energy. Among them, energy storage will become an important resource in future system. However, due to cost constraints equipment investment, large-scale deployment is difficult. Therefore, this article based on “sharing concept” study optimization technology regional integrated operation that takes into account shared storage....
Objectives This study aimed to explore the value of D-dimer levels in predicting treatment efficacy and prognosis advanced esophageal squamous cell carcinoma (ESCC) treated with programmed death protein-1/programmed death-ligand 1 (PD-1/PD-L1) inhibitors. Methods The retrospectively analyzed 233 ESCC patients who received PD-1/PD-L1 optimal cut-off values for platelets, fibrinogen, were calculated based on maximally selected rank statistics patients’ overall survival. Univariate multivariate...
Lower limb spasticity and clonus are common sequelae after cerebral stroke. An important part of their etiopathogenesis has been related to the peripheral component spasticity. Rheological properties tissues seem be involved. Several studies highlighted anatomical functional changes in connective structures. The fasciae might implicated pathological process. Thus, this study intends investigate effect Fascial Manipulation (FM) technique on triceps surae stroke patients through a clinical...
Purpose: To investigate the effect of norcantharidin (NCTD) on cyclophosphamide (CY)-induced immunosuppression and leukopenia in mice.
 Methods: Cyclophosphamide (80 mg/kg/day) was intraperitoneally administered to mice from day 1 3 9, 4 10, NCTD (1, 2 mg/kg) administered. The counts white blood cells (WBC), red (RBC) platelets (PLT) peripheral were determined, followed by evaluation mouse spleen thymus indices. Histopathological examination performed using hematoxylin-eosin (H & E)...