Yuchen Wu

ORCID: 0000-0002-5314-9920
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About
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Research Areas
  • Inflammatory Biomarkers in Disease Prognosis
  • Pancreatic and Hepatic Oncology Research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Organ Transplantation Techniques and Outcomes
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Gastric Cancer Management and Outcomes
  • Cancer-related gene regulation
  • RNA Research and Splicing
  • Epigenetics and DNA Methylation
  • Airway Management and Intubation Techniques
  • Trace Elements in Health
  • Economic and Financial Impacts of Cancer
  • Direction-of-Arrival Estimation Techniques
  • Esophageal Cancer Research and Treatment
  • Global Cancer Incidence and Screening
  • Erythrocyte Function and Pathophysiology
  • Inflammasome and immune disorders
  • Drug-Induced Hepatotoxicity and Protection
  • Multiple and Secondary Primary Cancers
  • Kawasaki Disease and Coronary Complications
  • Colorectal Cancer Screening and Detection
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Colorectal Cancer Surgical Treatments
  • Ovarian cancer diagnosis and treatment

Hangzhou Medical College
2024

Zhejiang Provincial People's Hospital
2024

Zhejiang Cancer Hospital
2022-2024

Jilin University
2024

National Taiwan University
2024

University of Chinese Academy of Sciences
2022-2023

Wenzhou Medical University
2022-2023

Xiamen University
2023

Cancer Hospital of Chinese Academy of Medical Sciences
2023

Chinese Academy of Sciences
2023

This prospective randomized clinical study is aimed to evidence the reproductive impairment of frequent scrotal heat exposure. A total 20 normozoospermic subjects were randomly divided into two groups undergo testicular warming in a 43 °C water bath 10 times, for 30 min each time; group 1 underwent consecutive days and those 2 once every 3 days. Sperm chromatin structure assay (SCSA), sperm mitochondrial membrane potential (MMP), apoptosis, seminal plasma-soluble Fas (sFas) analyzed before...

10.1111/andr.12228 article EN Andrology 2016-07-13

Background Previous studies have suggested that the ratios of immune-inflammatory cells could serve as prognostic indicators in ovarian cancer. However, which these is superior indicator cancer remains unknown. In addition, on value platelet to neutrophil ratio (PNR) are still limited. Methods A cohort 991 patients was analyzed present study. Receiver operator characteristic (ROC) curves were utilized choose optimal cut-off values inflammatory biomarkers such lymphocyte (NLR), monocyte...

10.3389/fimmu.2023.1177403 article EN cc-by Frontiers in Immunology 2023-06-30

Objectives It is significant to develop effective prognostic strategies and techniques for improving the survival rate of gallbladder carcinoma (GBC). We aim prediction model from multi-clinical indicators combined artificial intelligence (AI) algorithm prognosis GBC. Methods A total 122 patients with GBC January 2015 December 2019 were collected in this study. Based on analysis correlation, relative risk, receiver operator characteristic curve, importance by AI between clinical factors...

10.3389/fonc.2023.1171837 article EN cc-by Frontiers in Oncology 2023-05-10

Differences in epidemiology, pathological features, and molecular pathogeneses have been observed according to primary tumor location colorectal cancer (CRC). However, predicting CRC survival by remains controversial. Therefore, we compared the characteristics, prognoses of right-side colon (RCC), left-side (LCC), rectal (RECC) among Chinese patients with CRC. We evaluated 4,426 stage I-III between January 2008 July 2014from Fudan University Shanghai Cancer Center. All were grouped locations...

10.18632/oncotarget.16305 article EN Oncotarget 2017-03-17

Abstract We aimed to develop machine learning (ML)-based algorithms assist physicians in ultrasound-guided localization of cricoid cartilage (CC) and thyroid (TC) cricothyroidotomy. Adult female volunteers were prospectively recruited from two hospitals between September December, 2020. Ultrasonographic images collected via a modified longitudinal technique. You Only Look Once (YOLOv5s), Faster Regions with Convolutional Neural Network features (Faster R-CNN), Single Shot Detector (SSD)...

10.1007/s10278-023-00929-3 article EN cc-by Deleted Journal 2024-01-10

Background: Breast cancer imposes a significant economic burden on families, often leading to catastrophic health expenditure (CHE). Patients face complex treatments and increased medical costs, particularly among the elderly population.Methods: The study utilized data from 600 households with breast survivors in Chinese hospitals, collected under "System of Health Accounts 2011 (SHA 2011)" project 2021. Employing retrospective cross-sectional design, logistic regression backpropagation...

10.2139/ssrn.4812479 preprint EN 2024-01-01

Coactivator-associated arginine methyltransferase 1 (CARM1) is significant as a key member of the PRMT family, crucial for regulating methylation, and its association with colorectal cancer underscores potential therapeutic target. Consequently, CARM1 inhibitors have emerged agents in treatment valuable chemical tools research. Despite steady progress inhibitor research, challenges persist discovering effective, isoform-selective, cell-permeable, vivo-active cancer. This review summarizes...

10.1080/07357907.2024.2354798 article EN Cancer Investigation 2024-05-27

Objectives This study aimed to explore the value of D-dimer levels in predicting treatment efficacy and prognosis advanced esophageal squamous cell carcinoma (ESCC) treated with programmed death protein-1/programmed death-ligand 1 (PD-1/PD-L1) inhibitors. Methods The retrospectively analyzed 233 ESCC patients who received PD-1/PD-L1 optimal cut-off values for platelets, fibrinogen, were calculated based on maximally selected rank statistics patients’ overall survival. Univariate multivariate...

10.1177/03936155241262045 article EN cc-by-nc The International Journal of Biological Markers 2024-06-17

Background and Aims. There is currently a lack of suitable hematological markers as complement to pathological factors in predicting the prognosis patients with gallbladder cancer. The study aimed investigate clinical value preoperative fibrinogen levels assessing cancer after radical surgery. Methods. retrospectively analyzed 260 who underwent resection. Time-dependent receiver operating characteristic (ROC) curves were used calculate optimal cut-off values carcinoembryonic antigen (CEA),...

10.1155/2022/5370539 article EN cc-by Advanced Gut & Microbiome Research 2022-09-26
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