- Cytomegalovirus and herpesvirus research
- Radiopharmaceutical Chemistry and Applications
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Legionella and Acanthamoeba research
- HER2/EGFR in Cancer Research
- Advanced Sensor and Energy Harvesting Materials
- Helicobacter pylori-related gastroenterology studies
- Body Composition Measurement Techniques
- Advanced Decision-Making Techniques
- Hypertrophic osteoarthropathy and related conditions
- AI in cancer detection
- Radiomics and Machine Learning in Medical Imaging
- Advanced Materials and Mechanics
- Rheumatoid Arthritis Research and Therapies
- Polyamine Metabolism and Applications
- Autoimmune Bullous Skin Diseases
- Monoclonal and Polyclonal Antibodies Research
- Customer churn and segmentation
- MXene and MAX Phase Materials
- Strategic Planning and Analysis
- Cardiovascular Health and Disease Prevention
- Colorectal Cancer Surgical Treatments
- Micro and Nano Robotics
Chinese Academy of Sciences
2020-2025
Shanghai University of Engineering Science
2024-2025
Institute of Biophysics
2022-2025
Sichuan University
2021-2024
Qilu Hospital of Shandong University
2019-2024
Southern Medical University
2024
Nanfang Hospital
2024
West China Hospital of Sichuan University
2021-2023
First Affiliated Hospital of Guangzhou Medical University
2021
State Key Laboratory of Respiratory Disease
2021
Background and aims Endoscopic diagnosis of early esophageal squamous cell cancer (ESCC) is complicated dependent on operators' experience. This study aimed to develop an artificial intelligence (AI) model for automatic ESCC. Methods Non‐magnifying magnifying endoscopic images normal/noncancerous lesions, ESCC, advanced (AEC) were retrospectively obtained from Qilu Hospital Shandong University. A total 10,988 5075 cases chosen training validation. Another 2309 1055 collected testing. One...
The trophoblast cell-surface antigen 2 (Trop2) is markedly overexpressed in breast cancers, with a particularly high incidence triple-negative cancer. therapeutic relevance of Trop2 expression underscored by the approval an antibody-drug conjugate for cancer treatment. However, there no predictive technique accurate whole-body mapping patients. In this study, we developed novel Trop2-specific molecular probe, [99mTc]Tc-MY6349, and evaluated its safety feasibility detecting using SPECT/CT...
Cytomegalovirus (CMV) reactivation is associated with adverse prognoses of critically ill patients. However, the epidemiology and predictors CMV in immunocompetent patients receiving mechanical ventilation (MV) are not clear. The aim this study was to investigate requiring MV.A single-center, prospective observational (conducted from June 30, 2017 July 01, 2018) a follow-up 90 days (September 29, that included 71 CMV-seropositive MV at 37-bed university hospital general intensive care unit...
Miss rate of colorectal neoplasia is associated with lesion histology, size, morphology, or location.We aim to compare the efficacy Linked color imaging (LCI) versus white light (WLI) for adenoma detection (ADR), sessile serrated lesions (SSLs), (SLs), advanced adenomas (AAs), diminutive (DLs), and flat (FLs) by using per-patient per-lesion analysis based on randomized controlled trials (RCTs).Systematic review meta-analysis.PubMed, Embase, Cochrane databases were searched through May 1st,...
Background Considering trophoblast cell surface antigen 2 (Trop2) is overexpressed in a wide range of human epithelial cancers, it presents an attractive target for the diagnosis and treatment multiple types cancer. Herein, we have developed Trop2-specific radiotracer, 68Ga-MY6349, present prospective, investigator-initiated trial to explore clinical values 68Ga-MY6349 PET/CT. Methods In this translational study, 90 patients with 15 cancer, who underwent PET/CT, were enrolled prospectively....
Augmentation index ( AI x) and subendocardial viability ratio SEVR ) are widely accepted indices of wave reflection myocardial oxygen demand relative to supply. This study aimed validate a new tonometric device IIM ‐2010A) for obtaining x from radial artery. A total 68 outpatients (32 men 36 women) aged 20 76 years (44.7±16.6 years) recruited health screening center participated in the study. was obtained pressure using HEM ‐9000 ‐2010A devices, while measured carotid with method by device....
Abstract Background and Aim Cresyl violet (CV) is a topical dye that allows simultaneous chromoendoscopy in vivo confocal laser endomicroscopy identification of neoplastic changes the lower gastrointestinal tract without intravenous injection fluorescein, but as yet no investigation has reported its application diagnosis gastric intestinal metaplasia (GIM). This study aims to assess feasibility well accuracy CV for GIM by using probe‐based (pCLE). Methods In this prospective, open‐label,...
Abstract Background and Aim The study aims to evaluate the feasibility of body mass index (BMI)‐based individualized small bowel preparation for computed tomography enterography (CTE). Methods In this prospective randomized controlled study, patients undergoing CTE were randomly assigned group or standardized group. Those in given different volumes mannitol solution based on BMI (1000 mL with < 18.5 kg/m 2 , 1500 ≤ 25 2000 ≥ ) while all asked consume 1500‐mL solution. images reviewed by...
Soft actuators are limited by single-mode driving technology, which poses challenges in dealing with complex and multidimensional movements. In this study, a multiresponsive soft actuator was fabricated integrating microwrinkling structure into an MXene-based film, enabling programmable motions. To achieve this, we introduced n-hexane the film preparation process utilized its rapid volatilization to accelerate shrinkage difference between substrate. This resulted anisotropic folding...
A 28-year-old woman had suffered from 6 years of chronic anemia symptoms and 4 repeated bouts incomplete small-intestine obstruction with unclear cause. retained video capsule endoscopy (VCE) 15 months previously shown multiple circular ulcers in the small intestine. She no history previous medication usage, including nonsteroidal anti-inflammatory drugs (NSAIDs). Laboratory tests showed iron deficiency (hemoglobin 65 g/L), slight hypoalbuminemia (36.6 positive occult blood her stool, while...
Abstract Background: Cytomegalovirus (CMV) reactivation is associated with adverse prognoses of critically ill patients. However, the epidemiology and predictors CMV in immunocompetent patients receiving mechanical ventilation (MV) are not clear. The aim this study was to investigate requiring MV. Methods: A single-center, prospective observational (conducted from June 30, 2017 July 01, 2018) a follow-up 90 days (September 29, that included 71 CMV-seropositive MV at 37-bed university...
Objective To investigate the effect of intra-articular tumor necrosis factor (TNF) inhibitor injection in patients with moderate to severe rheumatoid arthritis (RA) and values power Doppler ultrasonography evaluating injection. Methods RA knee and/or elbow ankle referred Department Rheumatology First Affiliated Hospital Xi'an Jiaotong University were enrolled receive 50 mg or 25 recombinant human factor-α receptor Ⅱ: IgG Fc fusion protein(TNFR: Fc) for after synovial fluid aspiration....
Abstract Background: Prophylactic interventions against osteoporosis require a determination of the factors that influence bone status during adulthood. This study aimed to investigate associations between body composition parameters (body height (BH), weight (BW), fat free mass (FFM), (FM), lower limb muscle (LLMM), (LLFM)), countermovement jump (CMJ) performance, and calcaneal stiffness (SI) in population young adults. Methods: The included 560 Chinese adults (369 females), aged 20-40...
Abstract Background: Cytomegalovirus (CMV) reactivation can seriously affect the clinical prognoses of critically ill patients. However, epidemiology and predictors CMV in immunocompetent patients with mechanical ventilation are not very clear. Methods: A single-center, prospective observational study (conducted from June 30, 2017 to July 01, 2018) a follow-up 90 days (September 29, that included 71 CMV-seropositive at 37-bed university hospital general intensive care unit (ICU) China....