A5100756029- Mitochondrial Function and Pathology
- Bone Tissue Engineering Materials
- Alzheimer's disease research and treatments
- Bone Metabolism and Diseases
- Oral microbiology and periodontitis research
- Advanced Optical Imaging Technologies
- ATP Synthase and ATPases Research
- Advanced Vision and Imaging
- Dental materials and restorations
- Autophagy in Disease and Therapy
- Dental Research and COVID-19
- Metabolism and Genetic Disorders
- Oral Health Pathology and Treatment
- Salivary Gland Disorders and Functions
- Dental Erosion and Treatment
- Dental Radiography and Imaging
- Graphene and Nanomaterials Applications
- Temporomandibular Joint Disorders
- Dental Implant Techniques and Outcomes
- dental development and anomalies
- Traffic Prediction and Management Techniques
- Ubiquitin and proteasome pathways
- Cancer, Hypoxia, and Metabolism
- Mesenchymal stem cell research
- Laser Applications in Dentistry and Medicine
Stomatology Hospital
2024
Sichuan University
2014-2024
State Key Laboratory of Oral Diseases
2014-2024
Guangdong Academy of Medical Sciences
2024
Southern Medical University
2024
Guangdong Provincial People's Hospital
2024
China Jiliang University
2021
XinHua Hospital
2020
Rutgers Cancer Institute of New Jersey
2014
Rutgers, The State University of New Jersey
2014
// Xiaoyan Li 1,2,* , Qifeng Yang Haiyang Yu 1 Lihua Wu 1,3 Yuhan Zhao Cen Zhang Xuetian Yue Zhen Liu Hao Bruce G. Haffty Zhaohui Feng Wenwei Hu 1,4 Department of Radiation Oncology, Rutgers Cancer Institute New Jersey, State University Brunswick, NJ, USA 2 Breast Surgery, Qilu Hospital, Shandong University, Ji’nan, China 3 First Affiliated Zhejiang Hangzhou, 4 Pharmacology, * These authors contributed equally to this work Correspondence: Hu, email: Feng, Keywords : LIF, breast cancer,...
Diabetes has adverse effects on the brain, especially hippocampus, which is particularly susceptible to synaptic injury and cognitive dysfunction. The underlying mechanisms strategies rescue such dysfunction are not well understood. Using a mouse model of type 2 diabetes (db/db mice) human neuronal cell line treated with high concentration glucose, we demonstrate aberrant mitochondrial morphology, reduced ATP production, impaired activity complex I. These abnormalities induced by imbalanced...
Oxygen deficiency is associated with various oral diseases, including chronic periodontitis, age-related alveolar bone loss, and mechanical stress-linked cell injury from orthodontic appliances. Nevertheless, our understanding of the impact hypoxia on periodontal tissues its biochemical mechanism still rudimentary. The purpose this research was to elucidate effects apoptosis human ligament stem cells (PDLSCs) in vitro underlying mechanism. Herein, we showed that cobalt chloride (CoCl2)...
Mitochondrial dysfunction and axonal degeneration are early pathological features of Alzheimer's disease (AD)-affected brains. The underlying mechanisms strategies to rescue it have not been well elucidated. Here, we evaluated mitochondrial transport function in AD subject-derived mitochondria. We analyzed kinetics human trans-mitochondrial "cybrid" (cytoplasmic hybrid) neuronal cells whose mitochondria were derived from platelets patients with sporadic compared these cybrid cell lines...
Osteogenesis and angiogenesis are tightly coupled processes during bone development formation. It is thus well known that the enhancement of vascularization great importance in tissue engineering. As a potential approach for repairing defects, constructs should therefore replicate essential components vivo microenvironments to promote cell osteogenic differentiation while at same time induce angiogenic response. In light standpoint above, combination human bone-derived scaffolds BMSCs...
Caspase-8 (CASP8) is a key controller of apoptosis, and its deregulation crucially involved in carcinogenesis. The aim the present study was to evaluate function CASP8 polymorphisms oral squamous carcinoma (OSCC) by evaluating risk associated with three single-nucleotide (SNPs) case-control Han Chinese patient population. A total 505 individuals clinically diagnosed OSCC 507 healthy controls were tested for SNPs rs3834129, rs13016963 rs1045485, using polymerase chain reaction-restriction...
Glucocorticoids (GCs) are frequently used for the suppression of inflammation in chronic inflammatory diseases. Excessive GCs usage is greatly associated with several side effects, including gingival ulceration, downward migration epithelium, attachment loss and disruption transeptal fibers. The mechanisms underlying GCs-induced impairments tissue remains poorly understood. Mitochondrial dysfunction various oral diseases, such as periodontitis, age-related alveolar bone hydrogen...
High mobility group box 1 (HMGB1) participates actively in oxidative stress damage and the latter relates closely to diabetic complications, including poor implant osseointegration. This article is aimed at investigating effects of HMGB1 on dysfunction bone marrow stromal cells (BMSCs) impaired osseointegration under environment. In vitro , BMSCs were treated with normal glucose (NG), high (HG), HG+glycyrrhizin (HMGB1 inhibitor, HG+GL). Cell proliferation, osteogenic behaviors, determined....
Abstract Background Using a rotary instrument or ultrasonic for tooth preparation is basic operation in the dental clinic that can produce significant number of droplets and aerosols. The droplet aerosol lead to transfer harmful germs. goal this study was analyze properties microbiological created by generated three common tooth-preparation instruments. Methods Streptococcus mutans UA159 used as biological tracer visualize passive sampling method map three-dimensional spatial distribution...
To analyze the effect of statins on cytokines levels in gingival crevicular fluid (GCF) and saliva clinical periodontal parameters middle-aged elderly patients with type 2 diabetes mellitus (T2DM).Systemically healthy controls (C group, n = 62), T2DM not taking (D 57) (S 24) were recruited. In each subjects (40-85 years) subclassified into h (periodontal health)group, g (gingivitis)group or p (periodontitis) group according to different conditions. 17 samples subject measured utilizing...
The traditional light-field coding algorithm used in a multi-projector-type display system requires sophisticated and complex three-dimensional modeling processes or parallax images obtained through dense capture. Here we propose an based on target pixel matching, which directly uses without process, can achieve more accurate reconstruction effect under sparse capture conditions. For the lack of information caused by capture, this compares similarity captured same object point different...
Abstract Glass-fibre-reinforced polyetherketoneketone (PEKK-GF) shows great potential for application as a dental implant restoration material; however, its surface bioinertness and poor antibacterial properties limit integration with peri-implant soft tissue, which is critical in the long-term success of restoration. Herein, functional magnesium (Mg) silver (Ag) ions were introduced into PEKK-GF by plasma immersion ion implantation (PIII). Surface characterization confirmed that morphology...