Galymzhan Issabekov
- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Neonatal and fetal brain pathology
- Pain Management and Treatment
- EEG and Brain-Computer Interfaces
- Musculoskeletal pain and rehabilitation
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Anesthesia and Pain Management
Saitama Prefectural Kumagaya Girls High School
2024
Capital Medical University
2019-2023
Capital University
2020
Abstract Objective To develop and validate a model to predict seizure freedom in children undergoing cerebral hemispheric surgery for the treatment of drug‐resistant epilepsy. Methods We analyzed 1267 surgeries performed pediatric participants across 32 centers 12 countries identify predictors at 3 months after surgery. A multivariate logistic regression was developed based on 70% dataset (training set) validated 30% (validation set). Missing data were handled using multiple imputation...
This study was undertaken to determine whether the vertical parasagittal approach or lateral peri-insular/peri-Sylvian hemispheric surgery is superior technique in achieving long-term seizure freedom. We conducted a post hoc subgroup analysis of HOPS (Hemispheric Surgery Outcome Prediction Scale) study, an international, multicenter, retrospective cohort that identified predictors freedom through logistic regression modeling. Only patients undergoing parasagittal, peri-insular/peri-Sylvian,...
Although hemispheric surgeries are among the most effective procedures for drug-resistant epilepsy (DRE) in pediatric population, there is a large variability seizure outcomes at group level. A recently developed HOPS score provides individualized estimation of likelihood freedom to complement clinical judgement. The objective this study was develop freely accessible online calculator that accurately predicts probability any patient 1-, 2-, and 5-years post-hemispherectomy. Retrospective...
PurposeEpilepsy is a prevalent neurological disorder characterised by repetitive seizures. It categorised into three types: generalised epilepsy (GE), focal (FE), and combined epilepsy. Correctly subtyping the important to select appropriate treatments. The types are mainly determined (i.e., diagnosed) their semiologies supported clinical examinations, such as electroencephalography magnetoencephalography (MEG). Although these examinations traditionally based on visual inspections of...
Background: A subset of pediatric epilepsy patients suffer from syndromes related to multi-lobar or hemispheric epileptogenic networks and diseases. Most these are refractory anti-seizure drug treatment, resulting in persistent disabling seizures, neurocognitive delay impaired quality life. In well-selected patients, surgery is associated with excellent seizure freedom rates relatively low complication rates. Nevertheless, 30% develop recurrence after cerebral surgery. The purpose this study...