Abstract Background Most studies have shown that maternal age is associated with birth weight. However, the specific relationship between each additional year of and weight remains unclear. The study aimed to analyze association Methods Raw data for all live births from 2015 2018 were obtained Medical Birth Registry Xi’an, China. A total 490,143 mother-child pairs full-term singleton ranging 20 40 years old included in our study. weight, gestational age, neonatal date, residence ethnicity...

Background: Naringenin, a member of the dihydroflavone family, has been shown to have protective function in multiple diseases.We previously demonstrated that naringenin played role hypertensive myocardial hypertrophy by decreasing angiotensin-converting enzyme (ACE) expression.The kidney is primary target organ hypertension.The present study tested effect on renovascular damage and explored underlying mechanism.Methods Results: An animal model hypertension was established performing...

Abstract Background Age at menarche (AAM) directly affects female estrogen levels, which play a vital role in bone metabolism. The exact relationship between mineral density (BMD) and AAM remains controversial. Thus, this study aimed to determine the association lumbar spine (LS) BMD postmenopausal women. Methods Our data were based on National Health Nutrition Examination Survey (NHANES) 2011–2018. was divided into three categories including ≤ 12, 13–15, ≥ 16 years, 12 years old category...

Objective: To study the effect of blood glucose variability on cardiac fibrosis and its mechanism in a model diabetic cardiomyopathy. Methods: A total 45 Sprague Dawley rats were randomly divided into three groups: control, control diabetes mellitus fluctuated groups. Fluctuated was induced by daily subcutaneous insulin intraperitoneal injections at different time points. Blood lipids glycosylated haemoglobin A1c assessed. Super oxide dismutase activity malondialdehyde level rat heart...

Quercetin, a flavonoid found in fruits and vegetables, is widely distributed as secondary metabolite the plant kingdom. Oxidative stress plays role pathogenesis of diabetes mellitus (DM). The present study investigated effects quercetin dietary supplementation on streptozotocin- (STZ-) induced hyperglycemic Arbor Acre (AA) broilers by determining levels fasting blood glucose (FBG), insulin (FINS), biochemical indicators, oxidative markers, inflammatory cytokines content, antioxidant enzymes...

Abstract Background Pregnancy has been considered a risk factor for the development of osteoporosis. Despite much research in this field, relationship between parity and bone mineral density (BMD) is still controversial. Therefore, we conducted study to investigate whether there was an association BMD femoral neck lumbar spine postmenopausal women. Methods Cross-sectional using data from National Health Nutrition Examination Survey (NHANES). Three linear regression models, Model 1...

The objective of the present study is to assess performance fasting blood glucose (FBG), postprandial (PBG), and glycated hemoglobin (HbA1c) as screening for coronary heart disease (CHD) in an inpatient population undergoing angiography. 1852 consecutive patients scheduled angiography were classified into Normal Glucose Tolerance (NGT), Impaired Regulation (IGR), diabetes, based on FBG, PBG, HbA1c. Correlations Gensini score with metabolism insulin resistance analyzed. associations between...

Abstract Aim/Introduction Both glucocorticoids and 5‐hydroxytryptamine (5‐ HT ) have been shown to induce insulin resistance ( IR in hepatocytes adipocytes. Here, we explore whether there is a correlation between them. Materials Methods Except for the control group, male rats were exposed dexamethasone treated with or without para‐chlorophenylalanine pCPA ), carbidopa 20 days. buffalo rat liver 3A BRL ‐3A) cells 24 h, , carbidopa, clorgiline 48 5‐ fluoxetine h. Whole‐body was determined by...

Abstract Background There was a wider disparity in the diet characterization among most studies on and pregnancy outcomes different countries, research northern China is limited. Therefore, purpose of present study that conducted northwest to understand dietary characteristics periconceptional women explore relationship between specific patterns with adverse outcomes. Methods A nested case-control from October 2017 November 2018 Shaanxi, China. Based prospective cohort 368 who were pregnant...

Abstract Background Clonidine stimulation test has been widely used in the diagnosis of growth hormone deficiency children with short stature a high level reliability. However, it may cause hypotension, which usually appears as headache, dizziness, bradycardia, and even syncope. It is well known that elevating beds to make patients’ feet above their cardiac might relieve this discomfort. real efficiency method remains be proved while best angle for elevated bed still unclear. Methods A total...

Objective: Our study aimed to estimate the number of hypertension patients with or without elevated body mass index (BMI), and assess their mortality risk. Methods: We used data from China Health Retirement Longitudinal Study (CHARLS) population hypertensive BMI. The risk BMI was estimated by using Nutrition Survey (CHNS) data. Cox proportional hazards models were hazard ratios 95% confidence intervals (CI). Results: In total, 23.02% adults, representing 117.74 (95% CI: 108.79, 126.69)...

Abstract Background: Most studies have shown that maternal age is associated with birth weight. However, the specific relationship between each additional year of and weight remains unclear. The study aimed to analyze association Methods: Raw data for all live births from 2015 2018 were obtained Medical Birth Registry Xi’an, China. A total 490143 mother-child pairs full-term singleton ranging 20 40 years old included in our study. weight, gestational age, neonatal date, residence ethnicity...

Background: Even today, thyroid cancer (THCA) remains an important threat to global health. For THCA patients, differentiated is the most commonly identified pathological subtype, and those diagnosed with papillary generally have good overall prognosis. poorly subtype THCA, patients aggressive disease course, higher risk of distant organ metastasis inferior Methods: RNA-seq data from TCGA GTEx databases are collected analyzed via R. The correlation between SEMA6B expression level as well...

Abstract Background: Most studies have shown that maternal age is associated with birth weight. However, the specific relationship between each additional year of and weight remains unclear. The study aimed to analyze association Methods: Raw data for all live births from 2015 2018 were obtained Medical Birth Registry Xi’an, China. A total 490143 mother-child pairs full-term singleton ranging 20 40 years old included in our study. weight, gestational age, neonatal date, residence ethnicity...

Abstract Research background Traditional risk factors for hypertrophic cardiomyopathy (HCM) have limited ability to predict poor survival outcomes in the medium long term after surgical septal myectomy (septal myectomy) patients with obstructive (HOCM) undergoing myectomy. Additionally, there is a lack of studies reporting relationship between left ventricular mass index (LVMI), an remodeling cardiomyopathy, and long-term prognostic methods: From June 2011 July 2016, 490 HOCM who completed...

Lorcaserin is a serotonergic agonist specific to the 5-hydroxytryptamine 2c receptor (5-HT 2C R) that FDA approved for long-term management of obesity with or without at least one weight-related comorbidity. can restrain patients’ appetite and improve insulin sensitivity hyperinsulinemia mainly through activating 5-HT R in hypothalamus. It known mCPP, kind agonist, decreases plasma concentration mice previous research our laboratory found mCPP inhibited glucose-stimulated secretion (GSIS) by...

Objective To investigate the effects of information services on lymphedema after breast cancer surgical treatment.Methods 120 patients were divided into two groups by convenience sampling method. The experimental group was provided risk reduction practices. factors considered included incidence lymphedema, symptoms, cognition and behavior in prevention, quality life.Results There no significant difference lymphedema(χ2=2.004,P>0.05). sense pain significantly less than control...

Abstract Background: Most studies have shown that maternal age is associated with birth weight. However, the specific relationship between each additional year of and weight remains unclear. The study aimed to analyze association Methods: Raw data for all live births from 2015 2018 were obtained Medical Birth Registry Xi’an, China. A total 490143 mother-child pairs full-term singleton ranging 20 40 years old included in our study. weight, gestational age, date newborns, date, residence...

Abstract Background Most studies have shown that maternal age was associated with birth weight. However, specific relationships between each additional year of and weight remain unclear. The study aimed to analyze the association at Methods Raw data for all live births from 2015 2018 obtained Medical Birth Registry Xi’an, China. 490143 mother-child pairs full-term singleton ranged 20 40 years old were included in our study. weight, gestational age, date newborns, date, residence, ethnicity...

Abstract Background: Maternal diet is critical to the development of gestational diabetes mellitus (GDM), but sparse studies have applied Chinese Dietary Balance Index for Pregnancy (DBI-P) assess maternal dietary quality and its relationship with GDM. We aimed examine GDM risk using newly developed DBI-P. Methods: included 1122 pregnant women from Tongji Birth Cohort (TJBC) in Wuhan, China. The semi-quantitative food frequency questionnaire (FFQ) was used obtain information during...

The incidence of diabetes mellitus (DM) was increasing in recent years, and it is important to screen those nondiabetic populations through health examination detect the potential risk factors for DM. We aimed find predictive effect on DM.We used public database from Rich Healthcare Group China evaluate onset colinear regression estimating relationship between dynamics index incident year time-dependent ROC calculate best cutoff predicting DM follow-up year. Kaplan-Meier method Cox were HR...