A5100385374- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Ureteral procedures and complications
- Uterine Myomas and Treatments
- Endometrial and Cervical Cancer Treatments
- Mesenchymal stem cell research
- Gynecological conditions and treatments
- Ovarian cancer diagnosis and treatment
- Reproductive System and Pregnancy
- Assisted Reproductive Technology and Twin Pregnancy
- Gestational Diabetes Research and Management
- Sarcoma Diagnosis and Treatment
- Advanced biosensing and bioanalysis techniques
- Genomics and Chromatin Dynamics
- Mosquito-borne diseases and control
- Renal and related cancers
- Malaria Research and Control
- Prenatal Screening and Diagnostics
- Anorectal Disease Treatments and Outcomes
- Cervical Cancer and HPV Research
- Diverticular Disease and Complications
- Cancer Diagnosis and Treatment
- Endometriosis Research and Treatment
- Angiogenesis and VEGF in Cancer
- RNA modifications and cancer
Second Affiliated Hospital of Shantou University Medical College
2022-2024
Shantou University
2019-2024
Hangzhou Women’s Hospital
2024
Rongcheng City People's Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Shandong University
2024
Shandong Provincial Hospital
2024
Shandong First Medical University
2024
Beijing Luhe Hospital Affiliated to Capital Medical University
2023
Jining Medical University
2023
Background: Syncytin, a retroviral envelope protein, is specifically expressed on trophoblast cells and mediates formation of the syncytiotrophoblast through fusogenic activity. Decreased expression Syncytin was found in fetal growth restriction placentas. Results: By generating an inducible knockout syncytin-a gene mice, we show specific disruption placental angiogenesis with abnormal two layers. Consistent defects observed vivo, conditioned medium collected from cells, following Syncytin-1...
Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is a promising candidate antigen for blood-stage malaria vaccine. However, antigenic variation and diversity of PfAMA-1 are still major problems to design universal vaccine based on this antigen, especially against domain I (DI). Detail understanding the gene polymorphism can provide useful information potential component. Here, general characteristics genetic structure effect natural selection DIs among Bioko P. isolates were...
Our purpose was to establish an in vitro model of the human placental barrier based on placenta slice culture and Ussing chamber. The villous morphology, beta-human chorionic gonadotropin (β-hCG), mRNA efflux function P-glycoprotein (P-gp), permeability fluorescent marker were confirmed. results showed that syncytiotrophoblast cells with abundant endoplasmic reticulum mitochondria covered a dense microvillus slice. β-hCG secretion levels chamber 274.13 ± 13.52 mIU/mL at 5 h, significantly...
Abstract Objectives To compare the efficacy and safety of percutaneous microwave ablation (PMWA) transcervical resection myoma (TCRM) for submucosal fibroids. Methods From January 2019 to 2021, we conducted a randomized controlled study involving patients with symptomatic uterine Questionnaires were also used measure fibroid symptom (UFS) scores quality life (QoL) before after treatment at 3, 6, 12 months. Outcomes, adverse events, hemoglobin recovery, volume both groups compared. Operation...
Abstract Background The assessment of retroperitoneal lymph node status in patients with locally advanced cervical cancer is still a problem. This study aimed to explore the choice these methods. Methods Laparoscopic lymphadenectomy was performed 96 cancer. positive rates metastasis were analyzed. values computed tomography minimum axial diameter (MAD) and squamous cell carcinoma antigen (SCC-Ag), their combination predicting compared. High-risk factors for common iliac (CILN) and/or...
Gestational diabetes mellitus (GDM) is a serious pregnancy complication that impacts both the mother's and infant's health. Its incidence escalating annually, posing risk to well-being of expectant mothers newborns. This paper delves into methylation patterns Pancreatic Duodenal Homeobox 1 (PDX1) gene, exploring its link outcomes in GDM patients. Methodologically, we rigorously selected participants based on specific inclusion exclusion criteria, gathering detailed clinical biochemical data....
Background This study aimed to investigate the perinatal factors and early neonatal outcomes of abnormal birth weight (ABW) in Hangzhou, China from 2015 2021. Methods A retrospective cohort was designed analyse data 76 847 newborns, which case groups included 3042 cases low (LBW) 2941 fetal macrosomia (MAC), 70 864 normal were as reference group. Results The incidence LBW MAC 3.96% 3.83% Prematurity (<37 weeks), multiple births, hospitalisation >7 days, anomalies, caesarean section,...
Objective To evaluate the clinical value of holographic image navigation in urological laparoscopic and robotic surgery. Methods The data patients were reviewed retrospectively for whom accepted surgery from Jan. 2019 to Dec. Beijing United Family Hospital other 18 medical centers, including 78 cases renal tumor, 2 bladder cancer, adrenal gland 1 cyst, case prostate sweat carcinoma with lymph node metastasis, pelvic metastasis after radical cystectomy. All underwent operations. In...
Mutation of the DNAJC12 gene is typically associated with non-progressive Parkinsonism, but also detectable in breast carcinoma where its contribution and mechanisms are unexplored. In carcinoma, ESR1 was positively correlated ERBB4, ERBB4. We used GEO2R tool to compare differential expression MCF-7 cells, following knockdown (GEO database, E-GEOD-27473 array), found decreased ERBB4 ESR1-silenced cells. The number identical genes having correlativity ESR1, DNAJC12, or 12,165 (66.41%). These...
Objective: To explore the indication and surgery scope for laparoscopic extraperitoneal lymphadenectomy in locally advanced cervical cancer. Methods: Laparoscopic was initially performed on patients with The results of preoperative computed tomography (CT) images serum level squamous cell carcinoma antigen (SCC-Ag) were analyzed, diagnostic efficiencies minimum axial diameter (MAD) lymph node CT≥0.5 cm, ≥1.0 SCC-Ag alone or combined to predict metastases compared. high-risk factors common...
The present study was to investigate the effects of toll-like receptor 4 on transplanted bone marrow stem cells in ischemic brain. Focal cerebral ischemia induced by permanent occlusion middle artery gene knockout mice and wild type control mice. Bone were injected into lateral ventricle. cylinder tests, vivo image, polymerase chain reaction array, etc. applied evaluate neurological function underlying mechanisms. On 10th d after artery, ratio right limb movement group 1 significantly higher...