Hongbo Li

ORCID: 0000-0001-7633-8786
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About
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Research Areas
  • Cannabis and Cannabinoid Research
  • Ureteral procedures and complications
  • Anesthesia and Pain Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Inflammatory mediators and NSAID effects
  • Congenital Diaphragmatic Hernia Studies
  • Knee injuries and reconstruction techniques
  • Anesthesia and Sedative Agents
  • Total Knee Arthroplasty Outcomes
  • Tracheal and airway disorders
  • Sleep and Wakefulness Research
  • Congenital Anomalies and Fetal Surgery
  • Neuroscience of respiration and sleep
  • Bladder and Urothelial Cancer Treatments
  • Spinal Cord Injury Research
  • Cardiac Structural Anomalies and Repair
  • Pain Mechanisms and Treatments
  • Adenosine and Purinergic Signaling
  • Cancer Cells and Metastasis
  • Plant chemical constituents analysis
  • Immune Response and Inflammation
  • Medicinal Plants and Neuroprotection
  • Orthopaedic implants and arthroplasty
  • Testicular diseases and treatments
  • Fungal Biology and Applications

Jiangxi Provincial People's Hospital
2021-2024

The Second Nanning People's Hospital
2024

Guangxi Medical University
2024

First Affiliated Hospital of Jiangxi Medical College
2024

Temple University
2012-2023

Beijing United Family Hospital
2019-2023

Xi'an Medical University
2023

Honghu People’s Hospital
2022

Chongqing Medical University
2018-2021

China International Science and Technology Cooperation
2020-2021

Aspergillus flavus is a well-known pathogenic fungus for both crops and human beings. The acquisition of resistance to azoles by A. leading more failures occurring in the prevention infection flavus. In this study, we found that thymol, one major chemical constituents essential oil Monarda punctate, had efficient fungicidal activity against led sporular lysis. Further studies indicated thymol treatment induced generation ROS NO spores, whereas accumulation was far later than response thymol....

10.1371/journal.pone.0155647 article EN cc-by PLoS ONE 2016-05-19

Chemokine, monocyte chemoattractant protein-1 (MCP-1), is a potential factor to cause cancer-induced bone pain (CIBP). NF-κB signaling very important in mediating the expression of chemokines and may have role CIBP. However, mechanism still unclear. This study investigates CIBP by regulating MCP-1/chemokine CC motif receptor-2 (CCR2) pathway.A rat model was established injecting Walker-256 cells into tibia medullary cavity. Nine days later, animals were intrathecally administrated with MCP-1...

10.1177/1744806918788681 article EN cc-by-nc Molecular Pain 2018-01-01

Infiltration of tumor-associated macrophages (TAMs) can promote tumorigenesis and development. C-C motif chemokine ligand 3 (CCL3) was reported to be derived from TAMs tumor cells facilitate the progression several cancers. Nevertheless, whether CCL3 colon adenocarcinoma (COAD) is unclarified. Peripheral blood monocytes-derived were polarized by conditioned medium COAD establish TAM-like (TAM1/2). RT-qPCR western blotting used for detection expression levels its receptors receptor 1 (CCR1)...

10.1002/tox.23675 article EN Environmental Toxicology 2022-11-08

Abstract Background Many surgeries have not reversed or prevented progressive symptomatic knee arthritis, and there is no consensus regarding the ideal repair reconstruction technique for meniscal root treatment. Additionally, a lack of studies comparing clinical efficacy evaluation different techniques. The aim present study to compare healing rates meniscus in treatment medial posterior tear (MMPRT) with arthroscopically assisted gracilis autograft transtibial pull-out technique. Methods...

10.1186/s12891-022-06067-1 article EN cc-by BMC Musculoskeletal Disorders 2022-12-14

Abstract The controversy surrounding whether serum total cholesterol is a risk factor for the graded progression of knee osteoarthritis (KOA) has prompted this study to develop an authentic prediction model using machine learning (ML) algorithm. objective was investigate plays significant role in KOA. This cross-sectional utilized data from public database DRYAD. LASSO regression employed identify factors associated with Additionally, six ML algorithms were conjunction clinical features and...

10.1038/s41598-024-69906-2 article EN cc-by Scientific Reports 2024-08-14

Abstract The standard treatment for aplastic anemia (AA) in young patients is a matched sibling hematopoietic stem cell transplant. Transfusion of chronic AA patient with allogeneic bone marrow–derived mesenchymal stromal cells (BMMSCs) currently being developed as cell-based therapy, and the safety efficacy such transfusions are continuously improved. Nevertheless, mechanisms by which BMMSCs exert their therapeutic effects remain to be elucidated. In this study, (MSCs) obtained from marrow...

10.1038/srep42488 article EN cc-by Scientific Reports 2017-02-14

Despite advancements in dental pain management, one of the most common reasons for emergency care is orofacial pain. Our study aimed to determine effects non-psychoactive Cannabis constituents treatment and related inflammation. We tested therapeutic potential two constituents, cannabidiol (CBD) β-caryophyllene (β-CP), a rodent model associated with pulp exposure. Sham or left mandibular molar exposures were performed on Sprague Dawley rats treated either vehicle, phytocannabinoid CBD (5...

10.3390/biom13050846 article EN cc-by Biomolecules 2023-05-16

Abstract Background Intravenous dexmedetomidine is known to attenuate stress response in patients undergoing laparoscopic surgery. We investigated whether the addition of highly selective alpha-2 adrenergic agonist into ropivacaine for ultrasound-guided transversus abdominis plane block could inhibit during surgery, and determined optimal dose it. Methods One hundred twenty-five gynecological surgery were included this prospective randomized double-blind study. Patients received general...

10.1186/s12871-019-0859-7 article EN cc-by BMC Anesthesiology 2019-10-11

The robot-assisted laparoscopic management of post-chemotherapy retroperitoneal metastasis and inferior vena cava tumor thrombus secondary to testicular cancer is a challenging task for urologists. A pathological examination 36-year-old Caucasian man who had undergone right radical orchiectomy showed mixed germ cell (70% embryonal 30% seminoma); he four prior courses cisplatin, etoposide, bleomycin chemotherapy was found have residual enlarged lymph nodes close the renal hilum 9.8 cm (pT1,...

10.1186/s13256-019-2200-y article EN cc-by Journal of Medical Case Reports 2019-08-26

INTRODUCTION: Spinal cord injury (SCI) is a significant public health problem. Our group has been exploring the role of cannabinoid receptor modulation in murine model SCI. previous work demonstrated improvement both motor and bladder function recovery mice treated with CB2-agonist (O-1966), CB1-antagonist (SR141716). In this study, we explore combined effects selective CB1 inhibition CB2 activation. METHODS: Female C57/BL6 were randomized into experimental control groups. The received IP...

10.1227/01.neu.0000333487.18324.36 article EN Neurosurgery 2008-06-01

Objective To evaluate the clinical value of holographic image navigation in urological laparoscopic and robotic surgery. Methods The data patients were reviewed retrospectively for whom accepted surgery from Jan. 2019 to Dec. Beijing United Family Hospital other 18 medical centers, including 78 cases renal tumor, 2 bladder cancer, adrenal gland 1 cyst, case prostate sweat carcinoma with lymph node metastasis, pelvic metastasis after radical cystectomy. All underwent operations. In...

10.3760/cma.j.issn.1000-6702.2020.02.010 article EN 2020-02-15

Objective To evaluate the clinical value of three-dimensional (3D) image reconstruction in urologic robot-assisted laparoscopic surgery. Methods From Sept. 2017 to Jun. 2018, 7 patients(3 male cases, 4 female cases) diagnosed with genitourinary tumors Beijing United Family Hospital were involved this study. The median age was 55 years(IQR 36-64 years). There 1 case renal tumor, adrenal gland retroperitoneal metastatic tumor post-nephrectomy, bladder neuroendocrine and urachal tumor....

10.3760/cma.j.issn.1000-6702.2018.09.012 article EN Zhonghua miniao waike zazhi 2018-09-15

Abstract Background: Intravenous dexmedetomidine is known to attenuate stress response in patients undergoing laparoscopic surgery. We investigated whether the addition of highly selective alpha-2 adrenergic agonist into ropivacaine for ultrasound-guided transversus abdominis plane block could inhibit during surgery, and determined optimal dose it. Methods: One hundred twenty-five gynecological surgery were included this prospective randomized double-blind study. Patients received general...

10.21203/rs.2.388/v3 preprint EN cc-by Research Square (Research Square) 2019-09-30

Abstract Background: Intravenous dexmedetomidine is known to attenuate stress response in patients undergoing laparoscopic surgery. We investigated whether the addition of highly selective alpha-2 adrenergic agonist into ropivacaine for ultrasound-guided transversus abdominis plane block could inhibit during surgery, and determined optimal dose it. Methods: One hundred twenty-five gynecological surgery were included this prospective randomized double-blind study. Patients received general...

10.21203/rs.2.388/v2 preprint EN cc-by Research Square (Research Square) 2019-04-25
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