A5100675140- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Systemic Lupus Erythematosus Research
- Pelvic floor disorders treatments
- Gout, Hyperuricemia, Uric Acid
- Monoclonal and Polyclonal Antibodies Research
- Toxin Mechanisms and Immunotoxins
- Chronic Lymphocytic Leukemia Research
- Viral Infections and Immunology Research
- Stroke Rehabilitation and Recovery
- Sexual function and dysfunction studies
- Pelvic and Acetabular Injuries
- Optimism, Hope, and Well-being
- Urticaria and Related Conditions
- Hernia repair and management
- Connective tissue disorders research
- Psoriasis: Treatment and Pathogenesis
- Clinical practice guidelines implementation
- Liver Disease Diagnosis and Treatment
- Wnt/β-catenin signaling in development and cancer
- Menopause: Health Impacts and Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Inflammasome and immune disorders
- Immune Cell Function and Interaction
- Virus-based gene therapy research
Shanghai University of Sport
2025
Beijing Friendship Hospital
2024
Capital Medical University
2024
Obstetrics and Gynecology Hospital of Fudan University
2024
China Medical University
2008-2022
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
2020
Liaoning University of Traditional Chinese Medicine
2020
Peking Union Medical College Hospital
2018
Chinese Academy of Medical Sciences & Peking Union Medical College
2018
The Royal Melbourne Hospital
2017
Background: Sexual activity is an integral part of life; it important to address sexual health after stroke, but this often poorly done.Objective: To assess the effectiveness a structured rehabilitation programme compared with written information alone regarding and psychological functioning (anxiety, depression, stress), functional independence quality life in Australian stroke cohort.Methods: A total 68 participants were randomized (treatment group; n = 35) or (control 33).Outcome measures...
miR-410-3p acts as an oncogene or a tumor suppressor in some malignancies. However, its role rheumatoid arthritis (RA) is unknown. The study was conducted to investigate the effect of on pathogenesis RA. Real-time RT-PCR used determine mRNA levels synovial tissues and fibroblast-like synoviocytes (FLSs). An ELISA performed examine production necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, matrix metalloproteinase (MMP)-9. Western blotting protein IκB-α, p-IκBα, p65, p-p65. Nuclear...
Background: Virtual reality (VR) is a useful therapeutic tool in various patient populations. Patients with cancer may benefit from VR during chemotherapy to address concerns like negative affect, stress, and physical side effects.Objectives: The aim of this study was evaluate the effects on pain, affect patients receiving chemotherapy.Methods: Ninety were randomized into control groups. group received 12-minute session while undergoing chemotherapy. Participants took surveys measuring...
This study aimed to assess the association between perceived social support (PSS) and fatigue roles of hope, optimism, general self-efficacy resilience as mediators or moderators on PSS-fatigue among Rheumatoid Arthritis (RA) patients in China.A multi-center, cross-sectional was conducted withinpatients diagnosed with RA northeast China, which 305 eligible inpatients were enrolled. The Multidimensional Fatigue Inventory, Scale Perceived Social Support, Herth Hope Index, Life Orientation Test...
As negative regulators in Wnt signaling, Secreted Frizzled-Related Proteins (SFRPs) are downregulated a series of human cancers; and specifically, some matrix metalloproteinases (MMPs), including MMP-2, MMP-7, MMP-9 MT1-MMP, frequently overexpressed gastric cancer. The aim this study is to determine the expression status SFRP5 cancer explore correlation between both that these MMPs Expression SFRP5, MT1-MMP was determined by real-time PCR, RT-PCR or Western blotting. methylation detected...
To evaluate the safety, tolerability, and efficacy of SHR4640, a highly selective urate transporter-1 inhibitor, in combination with febuxostat, patients primary hyperuricemia.In this randomized, double-blind, parallel-controlled phase II study, whose fasting serum uric acid (sUA) levels were ⩾ 480 μmol/L at screening gout or sUA 420 lasting for least 3 months without gout, either 540 comorbidities screening, enrolled. Patients randomized (1:1:1) to receive SHR4640 10 mg plus febuxostat 80...
BACKGROUND Pelvic organ prolapse (POP) involves pelvic herniation into the vagina due to floor tissue laxity, and vaginal structure is an essential factor. In POP, walls exhibit abnormal collagen distribution decreased fibroblast levels functions. The intricate etiology of POP prohibition transvaginal meshes in reconstruction surgery present challenges targeted therapy development. Human umbilical cord mesenchymal stromal cells (hucMSCs) limitations, but their exosomes (hucMSC-Exo) are...
This study aimed to investigate the current status and changing trend of nosocomial infection in a tertiary general hospital China, provide reference for prevention control healthcare-associated/acquired (HAI).A retrospective investigation clinical data HAI patients Dongying People's Hospital China from January 1, 2018, December 31, 2021, was carried out. The incidence different units sites, distribution pathogenic microorganisms, antimicrobial use were investigated.The 0.93%. It on rise...
Although malignancy and chronic inflammatory diseases seem to be associated with one another, gastric carcinoma (GC) systemic lupus erythematosus (SLE) remains a very rare association. A 63-year-old man presented 4-month history of unintentional decreased appetite, weight loss, fatigue, but no fever, abdominal pain, or other discomfort symptoms. Endoscopic examination revealed an irregular 5-cm mucosal lesion on the flexure. The pathology poorly differentiated adenocarcinoma (mainly signet...
In this historical cohort study, 236 patients with primary rheumatoid arthritis were treated the tumor necrosis factor inhibitors, etanercept or infliximab (n = 80), by conventional methods 156). Results revealed that 11 developed varying types of peripheral neuropathy at 1-2 years post-treatment (mean 16 months). The incidence in inhibitors treatment group was 8.8% (7/80), which significantly higher than (2.6%; 4/156). relative risk developing 3.41 (95% confidence interval: 1.03-11.31)....
BACKGROUND Pelvic organ prolapse (POP) involves pelvic herniation into the vagina due to floor tissue laxity, and vaginal structure is an essential factor. In POP, walls exhibit abnormal collagen distribution decreased fibroblast levels functions. The intricate etiology of POP prohibition transvaginal meshes in reconstruction surgery present challenges targeted therapy development. Human umbilical cord mesenchymal stromal cells (hucMSCs) limitations, but their exosomes (hucMSC-Exo) are...
Abstract Background the role of uric acid (UA) in chronic kidney disease (CKD) remains controversial. In this study, effects UA levels on risk function (KF) decline patients with normal or mildly decreased KF at baseline were investigated. Methods Data extracted from community-based Tongzhou Cohort Study. The cohort 4246 was divided into group (estimated glomerular filtration rate [eGFR] ≥ 90 mL/min/1.73 m2) (60 ≤ eGFR < m2). primary endpoint decline, which defined as a composite 30%...
pressure was 7.75cmH 2 O, average use rate 55.7%, and time 151.3 minutes.There no difference of AHI (P = 0.527) CPAP 0.136) between before after suvorexant.Improvement were observed in 0.004) 4 hours above 0.001) suvorexant.A rise 90% suvorexant.Discussion: In our current study, by administering suvorexant to patients using with poor adherence, adherence improved exacerbation OSAS noticed.Hence, it is effective administer this suggests the possibility that can be used safely.