Raquel Gómez Bravo
A5020633136- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- COVID-19 and healthcare impacts
- Breast Cancer Treatment Studies
- Intimate Partner and Family Violence
- Advanced Breast Cancer Therapies
- Anorectal Disease Treatments and Outcomes
- HER2/EGFR in Cancer Research
- Colorectal Cancer Screening and Detection
- Social Media in Health Education
- Health Systems, Economic Evaluations, Quality of Life
- Adolescent Sexual and Reproductive Health
- Healthcare cost, quality, practices
- Mobile Health and mHealth Applications
- Telemedicine and Telehealth Implementation
- Cancer Immunotherapy and Biomarkers
- COVID-19 and Mental Health
- Advanced Graph Theory Research
- Long-Term Effects of COVID-19
- COVID-19 Pandemic Impacts
- Social Sciences and Policies
- Vaccine Coverage and Hesitancy
- Pharmaceutical Practices and Patient Outcomes
- Dementia and Cognitive Impairment Research
- Hate Speech and Cyberbullying Detection
Centre Hospitalier de Luxembourg
2023-2025
University of Luxembourg
2016-2025
Hospital Clínic de Barcelona
2014-2024
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2017-2024
ESCP Business School
2023
Universidade Federal Fluminense
2018-2023
University of Birmingham
2023
ESCP Business School
2023
NIHR Birmingham Biomedical Research Centre
2023
National University of Avellaneda
2023
The main characteristics of mechanically ventilated ARDS patients affected with COVID-19, and the adherence to lung-protective ventilation strategies are not well known. We describe outcomes confirmed in COVID-19 managed invasive mechanical (MV).
Abstract Background Awake prone positioning (awake-PP) in non-intubated coronavirus disease 2019 (COVID-19) patients could avoid endotracheal intubation, reduce the use of critical care resources, and improve survival. We aimed to examine whether combination high-flow nasal oxygen therapy (HFNO) with awake-PP prevents need for intubation when compared HFNO alone. Methods Prospective, multicenter, adjusted observational cohort study consecutive COVID-19 acute respiratory failure (ARF)...
In oldest-old patients (>80), few trials showed efficacy of treating hypertension and they included mostly the healthiest elderly. The resulting lack knowledge has led to inconsistent guidelines, mainly based on systolic blood pressure (SBP), cardiovascular disease (CVD) but not frailty despite high prevalence in oldest-old. This may lead variation how General Practitioners (GPs) treat hypertension. Our aim was investigate treatment GPs oldest-olds across countries identify role that...
Early-stage triple-negative breast cancer (TNBC) displays clinical and biological diversity. From a standpoint, immune infiltration plays crucial role in TNBC prognosis. Currently, there is lack of genomic tools aiding treatment decisions for TNBC. This study aims to assess the effectiveness B-cell/immunoglobulin signature (IGG) alone, or combination with tumor burden, predicting prognosis response patients
Intimate partner violence (IPV) causes substantial physical and psychological trauma. Restrictions introduced in response to the COVID-19 pandemic, including lockdowns movement restrictions, may exacerbate IPV risk reduce access support services. This cross-sectional study examines during restrictions 30 countries from International Sexual HeAlth REproductive Health (I-SHARE) conducted July 20th, 2020, February, 15th, 2021. was a primary outcome measure adapted World Organization...
Most COVID-19 patients were treated in primary health care (PHC) Europe.To demonstrate the scope of PHC workflow during pandemic emphasising similarities and differences patient's clinical pathways Europe.Descriptive, cross-sectional study with data acquired through a semi-structured questionnaire 30 European countries, created ad hoc agreed upon among all researchers who participated study. GPs from each country answered approved questionnaire. Main variable: acute pathway. All variables...
Abstract Background During the COVID-19 pandemic, majority of patients received ambulatory treatment, highlighting importance primary health care (PHC). However, there is limited knowledge regarding PHC workload in Europe during this period. The utilization indicators could facilitate efficient monitoring and coordination pandemic response. objective study to describe for disease surveillance COVID-19’s impact Europe. Methods Descriptive, cross-sectional employing data obtained through a...
This article reflects on an experience during a predoctoral internship in Luxembourg, focused the development of scientific, intercultural, and professional skills. The took place two key institutions: Hospital Center Neuro-Psychiatrique Ettelbruck Luxembourg Centre for Systems Biomedicine (LCSB), both which offered international multidisciplinary perspective. Through participation innovative projects, such as Long COVID study, improvements were made skills project management, teamwork,...
Since the emergence of SARS-CoV-2, an increasing number people report long-term physical and psychological impairments. Research on immunological sequalae long COVID (LC) is growing, though its relationship with mental health remains underexplored. We investigated impairments associated LC, identify related symptom clusters, their symptoms pandemic-related variables. Cross-sectional descriptive study, using online questionnaire (September 2020 - December 2022) in German French, assessing...
Telemedicine is an important way to fill in the access gap in-person health care services during challenging times like pandemics. This study aimed investigate role that telemedicine played COVID-19 pandemic by multicountry comparison of use prior and pandemic. analyzes data from second wave International Sexual Health Reproductive study. included collected between April 2021 July 2022 8 countries, including Armenia (n=296), Egypt (n=889), Germany (n=138), Moldova (n=311), Nigeria (n=205),...
Abstract Background General practitioners (GPs) should regularly review patients’ medications and, if necessary, deprescribe, as inappropriate polypharmacy may harm health. However, deprescribing can be challenging for physicians. This study investigates GPs’ decisions in 31 countries. Methods In this case vignette study, GPs were invited to participate an online survey containing three clinical cases of oldest-old multimorbid patients with potentially polypharmacy. Patients differed terms...
Digital health technologies (DHTs) have become increasingly commonplace as a means of delivering primary care. While DHTs been postulated to reduce inequalities, increase access, and strengthen systems, how the implementation has realized in sub-Saharan Africa (SSA) care environment remains inadequately explored. This study aims capture multidisciplinary experiences professionals using explore strengths weaknesses, well opportunities threats, regarding use SSA settings. A combination...
Abstract Background: CDK7 has 3 critical roles in cancer: enhanced transcription of oncogenes and upregulation anti-apoptotic genes, acceleration the cell cycle through phosphorylation other CDKs driving estrogen receptor (ER) resistance to hormonal therapy. Inhibition is therefore a potential novel anti-cancer therapeutic strategy. Samuraciclib (CT7001), once daily oral inhibitor demonstrated favorable safety profile clinical activity combination with fulvestrant (SERD) patients HR+/HER2-...
Abstract Background For patients with mid and distal rectal cancer, robust evidence on long-term outcome causal treatment effects of transanal total mesorectal excision (TaTME) is lacking. This multicentre retrospective cohort study aimed to assess whether TaTME reduces locoregional recurrence rate compared laparoscopic (LapTME). Methods Consecutive cancer within 12 cm from the anal verge clinical stage II-III were selected three institutional databases. Outcome after (Nov 2011 - Feb 2018)...
This article describes the management of human resource and vaccination strategies in primary care twelve European countries relation to COVID-19 pandemic. All have found solutions increase their workforce care. Other healthcare professionals were incorporated support family doctors assuming tasks, under supervision coordination. The Commission had a crucial role production, purchase distribution vaccines. engagement campaign has an unequal participation different countries, although...
Abstract Background Neoadjuvant chemotherapy (NACT) and endocrine therapy (NET) are sometimes used to shrink hormone receptor-positive (HoR+)/HER2-negative breast cancer (BC) before surgery. These treatments can change the tumor on a molecular level, but impact patient outcomes remains unclear. There is also lack of detailed comparison between changes induced by both therapies. Methods We studied 186 patients with early-stage BC treated at our Institution either NACT or NET. Changes in...
Abstract This study examines the biological effects of palbociclib and ribociclib in hormone receptor-positive breast cancer, pivotal to HARMONIA prospective phase III clinical trial. We explore downstream impacts these CDK4/6 inhibitors, focusing on cell lines patient-derived tumor samples. treated HR+ cancer (T47D, MCF7, BT474) with or (100 nM 500 nM), alone combined fulvestrant (1 over periods 24, 72, 144 h. Our assessments included PAM50 gene expression, RB1 phosphorylation, Lamin-B1...
Abstract Background This article aims to examine patient safety in general practice during COVID-19. Methods In total, 5489 GP practices from 37 European countries and Israel filled the online self-reported PRICOV-19 survey between November 2020 December 2021. The outcome measures include 30 indicators on structure, process, outcome. Results data showed that structural problems often impeded COVID-19, as 58.6% of (3209/5479) reported limitations related their building or infrastructure....
Abstract Aim To identify the impact of COVID-19 measures on sexual behaviors and satisfaction in Luxembourg residents. Methods We conducted a cross-sectional online survey adults (> 18 years age) residing Luxembourg, while restrictions were place. The was available from January 15 to February 12, 2021 four languages (French, German, English Portuguese). Survey questions focused masturbation, cuddling, condom use, sex frequency, sexting, cybersex, watching porn, satisfaction. Results 557...