Alex Almuedo-Riera
A5101411383- COVID-19 Clinical Research Studies
- Mosquito-borne diseases and control
- Long-Term Effects of COVID-19
- Parasites and Host Interactions
- SARS-CoV-2 and COVID-19 Research
- Malaria Research and Control
- Viral Infections and Vectors
- Trypanosoma species research and implications
- Travel-related health issues
- Research on Leishmaniasis Studies
- Intensive Care Unit Cognitive Disorders
- Thermal Regulation in Medicine
- Vector-borne infectious diseases
- Respiratory Support and Mechanisms
- Hepatitis Viruses Studies and Epidemiology
- Dermatological diseases and infestations
- Cardiomyopathy and Myosin Studies
- Insect and Pesticide Research
- Sepsis Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Adrenal Hormones and Disorders
- COVID-19 epidemiological studies
- Parasitic Diseases Research and Treatment
- Zoonotic diseases and public health
- SARS-CoV-2 detection and testing
Universitat de Barcelona
2019-2025
Barcelona Institute for Global Health
2019-2025
Hospital Clínic de Barcelona
2020-2025
Evidence (Italy)
2021
Hospital Universitari i Politècnic La Fe
2020
Hospital Universitario de La Princesa
2020
Complejo Hospitalario de Pontevedra
2020
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2020
Hospital Clínico Universitario de Valencia
2020
Hospital General de Granollers
2017-2019
The main characteristics of mechanically ventilated ARDS patients affected with COVID-19, and the adherence to lung-protective ventilation strategies are not well known. We describe outcomes confirmed in COVID-19 managed invasive mechanical (MV).
Abstract Background Awake prone positioning (awake-PP) in non-intubated coronavirus disease 2019 (COVID-19) patients could avoid endotracheal intubation, reduce the use of critical care resources, and improve survival. We aimed to examine whether combination high-flow nasal oxygen therapy (HFNO) with awake-PP prevents need for intubation when compared HFNO alone. Methods Prospective, multicenter, adjusted observational cohort study consecutive COVID-19 acute respiratory failure (ARF)...
Abstract Background Critically ill patients with coronavirus disease 19 (COVID-19) have a high fatality rate likely due to dysregulated immune response. Corticosteroids could attenuate this inappropriate response, although there are still some concerns regarding its use, timing, and dose. Methods This is nationwide, prospective, multicenter, observational, cohort study in critically adult COVID-19 admitted into Intensive Care Units (ICU) Spain from 12th March 29th June 2020. Using...
Ivermectin has recently shown efficacy against SARS-CoV-2 in-vitro. We retrospectively reviewed severe COVID-19 patients receiving standard doses of ivermectin and we compared clinical microbiological outcomes with a similar group not ivermectin. No differences were found between groups. recommend the evaluation high-doses in randomized trials SARS-CoV-2.
Etiological diagnosis of febrile illnesses in returning travelers is a great challenge, particularly when presenting with no focal symptoms [acute undifferentiated (AUFI)], but crucial to guide clinical decisions and public health policies. In this study, we describe the frequencies predictors main causes fever travelers.Prospective European multicenter cohort study international (November 2017-November 2019). A predefined diagnostic algorithm was used ensuring systematic evaluation all...
Data on the clinical patterns and histopathology of SARS-CoV-2 related skin lesions, as well their relationship with severity COVID-19 are limited.Retrospective analysis a prospectively collected cohort patients infection in teaching hospital Barcelona, Spain, from 1 April to May 2020. Clinical, microbiological therapeutic characteristics, clinicopathological direct immunofluorescence immunohistochemical findings biopsies were analyzed.Fifty-eight out 2761 (2.1%) either consulting emergency...
We aimed to describe changes in characteristics and treatment strategies of hospitalised patients with COVID-19 detail the mortality trend over time.
Abstract Background The use of remdesivir has demonstrated a significant reduction in the time to recovery patients with COVID-19. However, impact on mortality is still controversial. Therefore, it necessary evaluate whether there specific subgroup whom an active antiviral therapy also reduces mortality. Methods Patients admitted for >48 h our hospital SARS-CoV-2 confirmed or suspected infection from February 2020 2021 were retrospectively analysed. primary outcome study was at 30...
Abstract Hospitalized patients with coronavirus disease 2019 (COVID-19) experiencing respiratory symptoms have different complications (inflammatory, co-infection, and thrombotic) that are identifiable by analytics patterns. Personalized treatment decisions decreased early mortality (odds ratio [OR] .144; 95% confidence interval [CI] .03–.686; P = .015). Increasing age (OR 1.06; .038) therapeutic effort limitation 9.684; < .001) were associated higher mortality.
Abstract Background In some patients the immune response triggered by SARS-CoV-2 is unbalanced, presenting an acute respiratory distress syndrome which in many cases requires intensive care unit (ICU) admission. The limitation of ICU beds has been one major burdens management worldwide; therefore, clinical strategies to avoid admission are needed. Objective We aimed describe influence tocilizumab on need transfer or death non-critically ill patients. Methods A retrospective study 171 with...
Objectives. In some patients the immune response triggered by SARS-CoV-2 is unbalanced, presenting an acute respiratory distress syndrome which in many cases requires intensive care unit (ICU) admission. The limitation of ICU beds has been one major burdens management around world; therefore, clinical strategies to avoid admission are needed. We aimed describe influence tocilizumab on need transfer or death non-critically ill patients. Material and methods. A retrospective study 171 with...
Abstract Background Identifying the causes of Acute Undifferentiated Febrile Illness (AUFI) is key to improve management returning travellers with fever. We evaluated a BioFire®FilmArray® prototype panel multiplex nucleic acid amplification tests (NAAT) targeting different relevant pathogens in Methods Prospective, multicentre study evaluate whole blood samples adult international presenting AUFI three European travel Clinics/Hospitals (November 2017–November 2019). 15 target analytes:...
Abstract Dexamethasone and tocilizumab have been associated with reduction in mortality, however, the beneficial effect is not for all patients impact on viral replication well defined. We hypostatized that C-reactive protein (CRP) could help identification of requiring anti-inflammatory therapy. Patients admitted > 48 h our hospital a confirmed or suspected infection by SARS-CoV-2 from February 2020 to 2021 were retrospectively evaluated. The primary outcome was mortality at 30 days....
Severe imported P. falciparum malaria is a source of morbi-mortality in non-endemic regions. WHO criteria don't accurately classify patients at risk complications. There need to evaluate new tools such as biomarkers better identify with severe malaria. A case-control study was conducted Barcelona, from January 2011–January 2021. Adult microbiologically confirmedP. were classified according criteria. Patients non-malarial fevers included controls. In each group, angiopoietin-1 (Ang-1),...
Background. Patterns of SARS‐CoV‐2 spread have varied by geolocation, with differences in seroprevalence between urban and rural areas, waves. Household is a known source new COVID‐19 infections, areas sub‐Saharan Africa being more prone than to transmission because limited access water some delayed health‐ seeking behaviour poor care. Objectives. To explore infection incidence households South (SA). Methods. We conducted prospective household cluster investigation 13 April 21 July 2021 the...
Abstract Background Diagnosis of undifferentiated non-malaria fevers (NMF) in returning travellers is a great challenge. Currently, there no consensus about the use empirical antibiotics with NMF. Although studies endemic areas showed that wide range pathogens implicated NMF are treatable doxycycline, role doxycycline fever still has to be explored. Methods Prospective European multicentre cohort study febrile international (November 2017—November 2019). Immunological and molecular...