Yi Chen

ORCID: 0000-0002-3901-4800
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Research Areas
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Wound Healing and Treatments
  • Pressure Ulcer Prevention and Management
  • Cystic Fibrosis Research Advances
  • Inhalation and Respiratory Drug Delivery
  • Infection Control and Ventilation
  • Neonatal Respiratory Health Research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Advanced Drug Delivery Systems
  • Radiomics and Machine Learning in Medical Imaging
  • COVID-19 diagnosis using AI
  • Advanced Breast Cancer Therapies
  • Lung Cancer Diagnosis and Treatment
  • Immune cells in cancer
  • Stoma care and complications
  • Botulinum Toxin and Related Neurological Disorders
  • Chronic Lymphocytic Leukemia Research
  • Marine Sponges and Natural Products
  • Ophthalmology and Visual Health Research
  • Nutrition and Health in Aging
  • Heavy Metal Exposure and Toxicity
  • Restless Legs Syndrome Research
  • Respiratory Support and Mechanisms
  • Hidradenitis Suppurativa and Treatments
  • Neutropenia and Cancer Infections

Guiyang Medical University
2022-2025

Fudan University
2024-2025

Shanxi Medical University
2021-2024

First Hospital of Shanxi Medical University
2021-2024

First Affiliated Hospital of Henan University
2023

First Affiliated Hospital of Soochow University
2017-2023

Soochow University
2014-2023

Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2023

Asus (China)
2022

Lanzhou University
2022

SARS-CoV-2 and other respiratory viruses spread via aerosols generated by infected people. Face masks can limit transmission. However, widespread use of disposable consumes tremendous resources generates waste. Here, a novel material for treating blown polypropylene filtration media used in medical-grade to impart antimicrobial activity is reported. To produce thin copper@ZIF-8 core-shell nanowires (Cu@ZIF-8 NWs), Cu NWs are stabilized using pluronic F-127 block copolymer, followed growth...

10.1002/adfm.202008054 article EN Advanced Functional Materials 2020-12-13

Aims and objectives This study aimed to determine the effect of home‐based lower limb resistance training (LLRT) in patients with stable COPD. Background Pulmonary rehabilitation (PR) COPD has been substantially investigated, but components differ among studies. Few works have focused on LLRT. Furthermore, few studies assessed muscle strength functional status by isokinetic/isometric extensor peak torque (PT) five‐repetition sit‐to‐stand test (FTSST), respectively. Design A randomised...

10.1111/jocn.14131 article EN Journal of Clinical Nursing 2017-10-27

Pseudomonas aeruginosa (PA) is a major pathogen causing morbidity and ultimately mortality in patients afflicted with cystic fibrosis (CF) lung disease. One important virulence factor, pyocyanin (PCN), blue, redox-active compound that secreted such copious amounts by PA the CF lungs it determines colour of expectorated sputum. In this study, we discovered physiological concentrations PCN inactivate airway epithelial vacuolar ATPase, resulting reduced expression trafficking transmembrane...

10.1111/j.1462-5822.2006.00696.x article EN Cellular Microbiology 2006-02-24

Pulmonary emphysema is a fatal lung disease caused by the progressive thinning, enlargement and destruction of alveoli that closely related to inflammation oxidative stress. Oxymatrine (OMT), as bioactive constituent traditional Chinese herbal Sophora flavescens, has great potential alleviate pulmonary via its anti-inflammatory antioxidative activities. administration most preferable way for treatment diseases. To improve in vivo stability retention OMT, OMT-loaded liposome with...

10.3390/molecules27113610 article EN cc-by Molecules 2022-06-04

Introduction: Early detection of lung cancer is one way to improve outcomes. Improving the nodules on chest CT scans important. Previous artificial intelligence (AI) modules show rapid advantages, which improves performance detecting in some datasets. However, they have a high false-positive (FP) rate. Its effectiveness clinical practice has not yet been fully proven. We aimed use AI assistance decrease FP. Materials and methods: images 60 patients were obtained. Five senior doctors who...

10.7150/ijms.69400 article EN cc-by-nc International Journal of Medical Sciences 2022-01-01

Objective: To develop and validate a radiomics nomogram for preoperative prediction of tumor necrosis in patients with clear cell renal carcinoma (ccRCC). Methods: In total, 132 pathologically confirmed ccRCC one hospital were enrolled as training cohort, while 123 from another served the independent validation cohort. Radiomic features extracted corticomedullary nephrographic phase contrast-enhanced computed tomography (CT) images. A signature based on optimal selected by consistency...

10.3389/fonc.2020.00592 article EN cc-by Frontiers in Oncology 2020-05-29

Abstract This retrospective study investigated the predictive value of Controlling Nutritional Status (CONUT) score in patients with intermediate-stage hepatocellular carcinoma (HCC) who received transarterial chemoembolization (TACE). Nomograms were developed to predict progression-free and overall survival (PFS, OS). The medical data 228 HCC treated TACE collected. apportioned 2 groups according CONUT score: low or high (<4, ≥4). Univariate multivariate analyses performed using Cox...

10.1017/s000711452100492x article EN British Journal Of Nutrition 2021-12-09

Comparing the efficacy of transarterial chemoembolization (TACE) combined with lenvatinib plus tislelizumab (TLT) TACE (TL) for unresectable hepatocellular carcinoma, particularly in determining which patients can benefit more from TLT treatment.

10.3389/fimmu.2024.1449663 article EN cc-by Frontiers in Immunology 2024-10-01

PURPOSE: The purpose of this study was to explore the perceptions and experiences patients with wound healing by secondary intention after removal a thoracic drainage tube. DESIGN: A qualitative phenomenological study. SUBJECTS AND SETTING: After tube, who were attending nursing clinic that provides WOC care population around 1 million people in Suzhou, China, invited participate. METHODS: Semistructured interviews digitally audio-recorded transcribed verbatim. Analysis data performed using...

10.1097/won.0000000000000617 article EN Journal of Wound Ostomy and Continence Nursing 2020-01-24

Purpose: Fatty oil of Descurainia Sophia (OIL) has poor stability and low solubility, which limits its pharmacological effects. We hypothesized that fatty nanoparticles (OIL-NPs) could overcome this limitation. The protective effect OIL-NPs against monocrotaline-induced lung injury in rats was studied. Methods: prepared by wrapping with polylactic-polyglycolide (PLGA-NPs) conducted vivo vitro experiments to explore anti-pulmonary hypertension (PH) effect. In vitro, we induced malignant...

10.2147/ijn.s436866 article EN cc-by-nc International Journal of Nanomedicine 2023-12-01

Background The score of Dyspnea, Eosinopenia, Consolidation, Acidemia and Atrial Fibrillation (DECAF) can be used to predict the in-hospital mortality patients with acute exacerbation chronic obstructive pulmonary disease (AECOPD). It is worth noting that DECAF first scoring standard combining biomarkers clinical variables. application helpful for improving accuracy system. In recent years, more reports studies paid attentions procalcitonin (PCT) in respiratory infectious diseases its value...

10.7754/clin.lab.2019.190612 article EN Clinical Laboratory 2020-01-01

Objective To explore experiences of patients with chronic obstructive pulmonary disease (COPD) to take up the home-based resistance training. Methods Twenty-two COPD who completed 12 weeks training were interviewed deeply, phenomenological analysis method was used. Results Though reading, analysis, reflection, separation, theme refining, two themes drawn: self-perceived benefits; pyhcological, social and healthy status barriers on taking persisting in...

10.3760/cma.j.issn.1672-7088.2016.05.001 article EN ˜The œJournal of practical nursing 2016-02-11

Objective To evaluate the application of a mobile platform-based system in management fundus disease outpatient settings. Methods In departments disease,premature babies requiring eye examination under general anesthesia and adults intraocular surgery were enrolled as subjects. According to existing clinical practices,we developed that met requirements practices optimized management. Based on FileMaker database,the tablet computers used platform could also be run iPad PC terminals.Results...

10.3881/j.issn.1000-503x.2016.04.014 article EN PubMed 2016-08-01

Objective To investigate the parents′ requirement of children with acute leukemia during period lumbar puncture. Methods A total 105 parents puncture were selected by purposive sampling to complete questionnaire. Results The requirements was 3.53, in which top three ensuring safe and comfortable (3.92±0.54) score, information acquisition (3.79±0.65) score receiving support help (3.68±0.71) score. The had different specific care before after puncture. Conclusions Doctors...

10.3760/cma.j.issn.1674-2907.2015.17.014 article EN 2015-06-16

Objective To explore life experience in chronic obstructive pulmonary disease (COPD) patients with the habit of exercise for more than 5 years, to enhance confidence participating rehabilitation other patients, help medical staff pay attention guide COPD take up exercise. Methods The narrative research method qualitative was used analyze collected data. Results The study found that coping approach contradiction between and dyspnea, ability live together peacefully enthusiasm...

10.3760/cma.j.issn.1672-7088.2016.10.009 article EN ˜The œJournal of practical nursing 2016-04-01
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