A5100653755- Histone Deacetylase Inhibitors Research
- Neuroblastoma Research and Treatments
- Cancer-related molecular mechanisms research
- Parallel Computing and Optimization Techniques
- Crystallography and molecular interactions
- Peptidase Inhibition and Analysis
- Software System Performance and Reliability
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Distributed systems and fault tolerance
- Birth, Development, and Health
- Real-Time Systems Scheduling
- Embedded Systems Design Techniques
- RNA Research and Splicing
- Distributed and Parallel Computing Systems
- Signaling Pathways in Disease
- Cancer, Hypoxia, and Metabolism
- Immunotherapy and Immune Responses
- Advanced Data Storage Technologies
- Pregnancy and preeclampsia studies
- Pediatric Urology and Nephrology Studies
- Gestational Diabetes Research and Management
- Immune cells in cancer
- Security and Verification in Computing
- Software Testing and Debugging Techniques
Wuhan Children's Hospital
2022-2025
Huazhong University of Science and Technology
2017-2025
Union Hospital
2017-2023
Union Hospital
2022-2023
Peking University
2002-2022
First Affiliated Hospital of Xi'an Jiaotong University
2022
Sichuan University
2015-2022
Inner Mongolia University
2022
Chengdu University
2017-2022
Beijing Center for Disease Prevention and Control
2021
To describe the trends of incidence and mortality cervical cancer in different age groups regions from 1990 to 2019.An international comparative study based on Global Burden Disease (GBD) estimates.Data were publicly available individuals not involved.We collected detailed information GBD between 2019. Average annual percentage changes (AAPCs) age-standardised rate (ASIR ASMR) cancer, by group region, calculated quantify temporal trends.Globally, absolute numbers incident cases deaths...
Energy poverty is one of the main challenges facing humanity in 21st century. Research on energy becoming a common focus scholars many areas. Bibliometrics can help researchers dig deep into information specific research fields from quantitative perspective. In this study, we collected 1018 papers field published period 1999–2019 Web Science databases and conducted bibliometric analysis them. Cleaning screening sample papers, matrix construction, visualization were performed using...
Emerging evidence links per- and polyfluoroalkyl substances (PFAS) exposure metabolic disruptions to fetal growth retardation. However, earlier studies on singletons couldn't fully account for genetic factors. Therefore, we used a co-twin control study design identify cord metabolomic signatures of PFAS assess its mediating role in twin birthweight discordance. We analyzed 204 neonates born from the Wuhan Twin Birth Cohort (August 2016-January 2018). Cord serum concentrations untargeted...
Most test suite reduction techniques aim to select, from a given suite, minimal representative subset of cases that retains the same code coverage as suite. Empirical studies have shown, however, suites reduced in this manner may lose fault detection capability. Techniques been proposed retain certain redundant so reduce loss fault-detection capability, but these still do concede some degree loss. Thus, be applicable only where loose demands are placed on upper limit In work we present an...
This paper introduces a programming interface called PARRAY (or Parallelizing ARRAYs) that supports system-level succinct for heterogeneous parallel systems like GPU clusters. The current practice of software development requires combining several low-level libraries Pthread, OpenMP, CUDA and MPI. Achieving productivity portability is hard with different numbers models GPUs. extends mainstream C novel array types distinct features: 1) the dimensions an type are nested in tree, conceptually...
Rationale: T-cell-redirecting bispecific antibodies (bsAbs) and trispecific (tsAbs) designed to recognize different epitopes or antigens have emerged as promising cancer therapies.Current approaches are all include another antibody specific the site of primary antibody, molecular structures generally established.However, dimensions target molecule epitope location play a key role in efficiency immunological synapse (IS) formation subsequent activities, therefore connection flexibility these...
Abstract Background Limited evidence exists regarding the association between gestational diabetes mellitus (GDM) and elevated levels of thyroid-stimulating hormone (TSH) in newborns. Therefore, this study aimed to investigate potential risk TSH infants exposed maternal GDM, considering type number abnormal values obtained from 75-gram oral glucose tolerance test (OGTT). Methods A population-based, prospective birth cohort was conducted Wuhan, China. The included women who underwent GDM...
Fatty acid synthase (FASN) promotes tumor progression in multiple cancers. In this study, we comprehensively examined the expression, prognostic significance, and promoter methylation of FASN, its correlation with immune cell infiltration pan-cancer. Our results demonstrated that elevated FASN expression was significantly associated an unfavorable prognosis many cancer types. Furthermore, DNA can be used as a marker. Importantly, high levels were negatively correlated 35 different...
Self-healing systems focus on how to reducing the complexity and cost of management dependability policies mechanisms without human intervention. This position paper proposes a systematic approach self-healing via dependable architecture reflective middleware. Firstly, differences between traditional are illustrated construction computing model. Secondly, middleware is incorporated into model for investigating feasibility benefits implementing by Thirdly, architectures introduced providing...
Effective power management has become a key concern in the design of wireless sensor networks. Dynamic refers to strategies which selectively switch between several states device during runtime order achieve tradeoff consumption and performance. In this article, we present novel methodology that exploits current model-checking technology for automatic synthesis dynamic management. The generic system model is modeled as network timed games. And objectives are expressed queries. Subsequently,...
Abstract Gestational diabetes mellitus (GDM) is a common complication of pregnancy with adverse effects on both mothers and fetuses. The relationship between GDM clinical information has been largely investigated; however, the role laboratory features genetic components in are relatively understudied, especially Chinese population. In this study, we recruited 21,813 pregnant women investigated risk factors for from environmental aspects. addition to serum fasting glucose urine measured first...
Abstract SARS-CoV-2 infection in human can cause medical complications across various tissues and organs. Despite of the advances to understanding pathogenesis SARS-CoV-2, its tissue tropism interactions with host cells have not been fully understood. Existing clinical data suggested possible skeleton system. In present study, we found that authentic could efficiently infect mouse bone marrow-derived macrophages (BMMs) alter expression macrophage chemotaxis osteoclast-related genes....
Energy saving is a crucial concern in embedded real time systems. Many RT-DVS algorithms have been proposed to save energy while preserving deadline guarantees. This paper presents novel approach evaluate using statistical model checking. A scalable framework for evaluation, which the relevant components are modeled as stochastic timed automata, and evaluation metrics including utilization bound, efficiency, battery awareness, temperature awareness expressed queries. Evaluation of these...